Discovering the link between nutrition and skin aging

Schagen, Silke; Zampeli, Vasiliki; Makrantonaki, Evgenia; Zouboulis, Christos C.

doi:10.4161/derm.22876

Cited by 190 publications

(126 citation statements)

References 114 publications

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“…Very many tests and scientific experiments demonstrate that the persons who are eating a diet rich in antioxidants and take a supplement of antioxidants, live longer and healthier (Schagen et al, 2012).…”

Section: Resultsmentioning

confidence: 99%

One Can Slow Down the Aging through Antioxidants

Aversa¹,

Petrescu²,

Apicella³

et al. 2016

American Journal of Engineering and Applied Sciences

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Free radicals are natural nanoparticles which are doing their part well defined in the human cell, but then they must be annihilated or eliminated to not destroy the cell or another part of our body. It has been shown that residual free radicals in the body are responsible for the aging. The role to annihilate them is ful-filled by the antioxidants. Antioxidants are a group of compounds produced by the organism or that occur naturally in many foods. Antioxidants work together in the human body to maintain health and vigor, especially during the last decades of life. They do this by protecting us from harm caused by free radicals that can destroy skin and tissues healthy cells of the organism. Antioxidants are chemical compounds with many and varied applications. Naturally present in our diet, through fruits, vegetables, tea or red wine, they are recognized to be good for health. In fact, antioxidants protect our body's proteins and nucleic acids from oxidation. In the industry, antioxidants are also used as food additives to increase the shelf life of food. They are also present in the packaging or the wheels of cars because they prevent synthetic materials from becoming crumbly and brittle. Finally, in the cosmetics industry, creams containing antioxidants are known for their anti-aging properties. An antioxidant is a molecule that decreases or prevents the oxidation of other chemicals. Oxidation is part of an oxidation-reduction reaction that transfers electrons from a substance to an oxidizing agent. This reaction can produce radicals that cause destructive chain reactions. However, whatever the field of application, the unstable nature of antioxidants is a problem: The molecules degrade rapidly and have a particularly limited power of action over time.

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Section: Resultsmentioning

confidence: 99%

One Can Slow Down the Aging through Antioxidants

Aversa¹,

Petrescu²,

Apicella³

et al. 2016

American Journal of Engineering and Applied Sciences

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“…Although additional research to explain the causes and mechanisms of lycopene deficiency in ageing is required, it is clear now that correction of carotenoid deficiency in older individuals may have anenormous impact on their health status. Moreover, lycopene has to suppress activation of them TOR/AMPK cascade,a major metabolic pathway linked to ageing (Menendez et al 2013).There are numerous pieces of clinical evidence suggesting that lycopene supplementation prevents osteoporosis and incidence of bone fractures (Sacco et al 2013), improves pulmonary function (Samba et al 2012), delays skin ageing (Schagen et al 2012), and enhances physical performance in elderly patients (Alipanah et al 2009). The set of clinical consequences of lycopene deficiency is greatly enlightened by the solid body of clinical evidence revealing the crucial role of lycopene in maintaining prostate health and its ability to prevent prostate cancer in elderly males (Mariani et al 2014).…”

Section: Lycopene and Cancermentioning

confidence: 99%

Lycopene and human health-A review

Kaur

Sandal

Dhillon

2017

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Functional and nutraceutical foods have shared the disease load of huge population. This has led to the consumption of plant-based phytonutrients act as preventives agents when taken as dietary supplements. Their health promoting potentials are due to presence of functional ingredients. The antioxidant properties of lycopene are thought to be primarily responsible for its beneficial properties. Lycopene bioavailability, tissue distribution, metabolism, excretion, and biological actions in humans are beginning to accumulate although much additional research is necessary. Lycopene is an important carotenoids.These are found to be very beneficial for maintaining a good health and helps in preventing cancer, cardiovascular and other diseases.

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“…Schagen et al [15] showed that the findings of Scarmo et al suggest that human skin, is relatively enriched in lycopene and β-carotene, compared with lutein and zeaxanthin, possibly reflecting a specific function of hydrocarbon carotenoids in human skin photoprotection.…”

Section: Beta-carotenementioning

confidence: 99%

“…Ten (10) sample preparations were done for the radical scavenging activity with ten (10) different concentrations such as 5,10,15,20,25,30,35,40,45 and 50 μg/ml.…”

Section: Plant Materials Standardized Testingmentioning

confidence: 99%

Free Radical Scavenging Activity and Antioxidants of <i>Hydrocotyle vulgaris </i>L<i>.</i> (Pennywort): Baseline Study in Developing Biocosmetic-Antidote for Pathological Aging

Ureta¹,

Mejico²,

Maranan³

2018

IJPPE

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Abstract. Pathological aging due to harmful free radicals and oxidative stress has been a serious threat to human health. Thus, the study aimed to evaluate the free radical scavenging activity, antioxidants, essential vitamins, and physicochemical properties of Hydrocotyle vulgaris L. (Pennywort) which could serve as basis in developing a biocosmetic antidote for pathological aging. H. vulgaris L. plant was harvested, air dried and then extracted via soxhlet. UV-vis spectroscopy was used for scavenging activity and antioxidants of the plant while High Performance Liquid Chromatography (HPLC) was applied for the identification of essential vitamins. Phytochemicals, pH and spreadability values of the plant were also tested. Results revealed that H. vulgaris L. has an abundant presence of flavonoid and alkaloid while traced presence of tannin. Good trend for scavenging activity was also observed exhibiting low absorbance of possible free radicals with IC 50 of 29.75 and antioxidant activity of 158.13 (Total Phenolics as gallic acid in %w/w). Meanwhile, β-carotene (10.4 mg/kg), Riboflavin (4.08mg/kg), and Vitamins C (70.2mg/kg) and E (26.9mg/kg) were also found in the plant. Non-irritating pH levels of 5.7 and 7.14 for 50% and 75% concentrations of the extracts with good spreadability value of 17.51 g•cm/sec (for 75% concentration) were also obtained. Based on the findings of the study, Pennywort has a very promising therapeutic characteristics with its good scavenging activity and antioxidants. Thus, the development of a biocosmetic product that could serve as an antidote for pathological aging from Pennywort appeared to be very apparent.

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Discovering the link between nutrition and skin aging

Cited by 190 publications

References 114 publications

One Can Slow Down the Aging through Antioxidants

One Can Slow Down the Aging through Antioxidants

Lycopene and human health-A review

Free Radical Scavenging Activity and Antioxidants of <i>Hydrocotyle vulgaris </i>L<i>.</i> (Pennywort): Baseline Study in Developing Biocosmetic-Antidote for Pathological Aging

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