Disease Activity and Related Variables in Patients with Psoriatic Arthritis

Yurdakul, Fatma Gül; Eser, Filiz; Bodur, Hatice; Gül, Ülker; Gönül, Müzeyyen; Oğuz, İşıl Deniz

doi:10.5606/tjr.2014.3400

Cited by 4 publications

(4 citation statements)

References 19 publications

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“…Our study has some limitations, such as the relatively low number of patients involved and the lack of a control group derived from the general population. However, it still provides important information regarding comorbid conditions that may be present in patients with PsA in the Turkish population …”

Section: Discussionmentioning

confidence: 99%

Comorbidities in patients with psoriatic arthritis: a comparison with rheumatoid arthritis and psoriasis

Nas

Karkucak

Durmuş³

et al. 2015

Int J of Rheum Dis

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Section: Discussionmentioning

confidence: 99%

Comorbidities in patients with psoriatic arthritis: a comparison with rheumatoid arthritis and psoriasis

Nas

Karkucak

Durmuş³

et al. 2015

Int J of Rheum Dis

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“…The BASDAI index was used in evaluating the disease activity of PsA patients. [ 28 , 29 ] This index includes six sections in which the duration and severity of fatigue, spinal and peripheral joint pain, sensitivity to pressure by touching, and morning stiffness are investigated. The patients answered each question on a 10-item Visual Analog Scale (VAS), taking into consideration their general condition in the last week.…”

Section: Methodsmentioning

confidence: 99%

“…It is calculated by taking into consideration the tender joint count in 28 joints, as well as the swollen joint count, erythrocyte sedimentation rate (ESR), and the VAS score. [ 31 ] DAS28 is an important tool in the evaluation of the disease activity of PsA patients[ 29 ] and is widely used in studies conducted with PsA patients. [ 32 ]…”

Section: Methodsmentioning

confidence: 99%

“…It is calculated by taking into consideration the tender joint count in 28 joints, as well as the swollen joint count, erythrocyte sedimentation rate (ESR), and the VAS score. 31 DAS28 is an important tool in the evaluation of the disease activity of PsA patients 29 and is widely used in studies conducted with PsA patients. 32 The VAS is a 10-item horizontal scale on which patients score the severity of their pain with "no pain=0" on one end and "very severe pain=10" on the other.…”

Section: Pregnantmentioning

confidence: 99%

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Examining the functions of the vascular endothelial growth factor/hypoxia-inducible factor signaling pathway in psoriatic arthritis

Kiliç,

Guzel Erdogan,

Baykul

et al. 2023

Arch Rheumatol

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Objectives: The present study aimed to examine the roles of the vascular endothelial growth factor (VEGF), hypoxia-inducible factor (HIF), and heme oxygenase-1 (HO-1) in psoriatic arthritis (PsA). Patients and methods: In this cross-sectional study conducted between November 2020 and May 2021, 64 patients (43 female, 21 male; mean age: 43.2±10.4 years; range, 22 to 60 years) with active PsA were included in the patient group, and 64 healthy volunteers (43 female, 21 male; mean age: 42.8±10.5 years; range, 23 to 61 years) were included in the control group. The demographic features of all cases were recorded. The following indices were used to assess the activity of PsA: Bath Ankylosing Spondylitis Disease Activity Index, Disease Activity Score in 28 joints (DAS28), and Visual Analog Scale. Additionally, Disease Activity in Psoriatic Arthritis (DAPSA) and Psoriasis Area and Severity Index (PASI) were used to evaluate the patients. The biochemical parameters of the patients were calculated. The serum levels of VEGF, HIF, and HO-1 were determined using an enzyme-linked immunosorbent assay. Results: When the molecule levels and clinical features of the groups were evaluated, it was found that the VEGF and HIF-1 levels were higher in the patient group compared to the control group (p<0.05). No difference was observed in the comparison of the HO-1 levels of the patient group and the control group (p<0.05). A positive correlation was found between VEGF, HIF-1, and HO-1 (p<0.05). A positive relationship was found between VEGF and HIF-1 and erythrocyte sedimentation rate, C-reactive protein, DAPSA score, and PASI score (p<0.05). It was also determined that there was a positive relationship between the HIF molecule and DAS28 (p<0.05). Conclusion: According to the results obtained in the present study, VEGF and HIF play a role in the etiology of PsA, and the observation of intermolecular correlation suggests that these molecules move together in pathogenesis.

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Plasma gelsolin levels in patients with psoriatic arthritis: a possible novel marker

et al. 2020

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Disease Activity and Related Variables in Patients with Psoriatic Arthritis

Cited by 4 publications

References 19 publications

Comorbidities in patients with psoriatic arthritis: a comparison with rheumatoid arthritis and psoriasis

Comorbidities in patients with psoriatic arthritis: a comparison with rheumatoid arthritis and psoriasis

Examining the functions of the vascular endothelial growth factor/hypoxia-inducible factor signaling pathway in psoriatic arthritis

Plasma gelsolin levels in patients with psoriatic arthritis: a possible novel marker

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