Disinfectants against SARS-CoV-2: A Review

Xiao, Shuqi; Yuan, Zhi Ming; Huang, Yi

doi:10.3390/v14081721

Cited by 34 publications

(20 citation statements)

References 132 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These results justify the washability of medical masks at 50 °C through five cycles and the possibility of reuse. These results are comparable to the functional properties of medical masks washed at 60 °C [ 20 ] with the addition of a disinfectant [ 7 , 32 ], whose ecological performance is questionable.…”

Section: Resultssupporting

confidence: 61%

Extending the Protection Ability and Life Cycle of Medical Masks through the Washing Process

et al. 2023

View full text Add to dashboard Cite

The reuse of decontaminated disposable medical face masks can contribute to reducing the environmental burden of discarded masks. This research is focused on the effect of household and laboratory washing at 50 °C on the quality and functionality of the nonwoven structure of polypropylene medical masks by varying the washing procedure, bath composition, disinfectant agent, and number of washing cycles as a basis for reusability. The barrier properties of the medical mask were analyzed before and after the first and fifth washing cycle indirectly by measuring the contact angle of the liquid droplets with the front and back surface of the mask, further by measuring air permeability and determining antimicrobial resistance. Additional analysis included FTIR, pH of the material surface and aqueous extract, as well as the determination of residual substances—surfactants—in the aqueous extract of washed versus unwashed medical masks, while their aesthetic aspect was examined by measuring their spectral characteristics. The results showed that household washing had a stronger impact on the change of some functional properties, primarily air permeability, than laboratory washing. The addition of the disinfectant agent, didecyldimethylammonium chloride, contributes to the protective ability and supports the idea that washing of medical masks under controlled conditions can preserve barrier properties and enable reusability.

show abstract

Section: Resultssupporting

confidence: 61%

Extending the Protection Ability and Life Cycle of Medical Masks through the Washing Process

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Environmental disinfection is necessary to prevent the transmission and infection waves of COVID-19. There are many disinfectants that can effectively inactivate SARS-CoV-2 (Xiao et al,2022). Lipid solvents, including EA (> 75%), formaldehyde (> 0.7%), isopropanol (> 70%), PI (> 0.23%), and sodium hypochlorite (> 0.21%), can be used to inactivate SARS-CoV-2 (Dhama et al,2021;Talic et al,2021).…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of different disinfectants and combinations against SARS-CoV-2 nucleic acid in COVID-19 quarantine wards

Zhang

Zhou

Zhu

et al. 2023

Preprint

View full text Add to dashboard Cite

Background To detect the contamination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the surroundings of coronavirus disease 2019 (COVID-19) patients and to evaluate the effectiveness of regular disinfectants and combinations against SARS-CoV-2 RNA. Methods We sampled the patients’ high contact surfaces in COVID-19 pediatric quarantine wards from April to June 2022. After conducting cleaning procedures using disinfectants, including trichloroisocyanuric acid (TCCA; 500, 1000, and 2000 mg/L), 5% hydrogen peroxide (H2O2), 0.5% povidone-iodine (PI), 75% ethanol (EA), 0.2% chlorhexidine gluconate (CHG), 0.2% quaternary ammonia compound (QAC), and five combinations, environmental samples in bathroom were collected at 0, 30 s, 10, 30, and 60 min. All samples were delivered to the medical laboratory for SARS-CoV-2 nucleic acid (ORF1ab and N) detection using real-time PCR. Results SARS-CoV-2 RNA was largely detected on surfaces in the COVID-19 quarantine ward and was highest in the floor, bathroom, and bed sheet. The ORF1ab and N genes remained detectable after 60 min of treatment with QAC, PI, EA, and CHG. H2O2 and TCCA2000 completely degraded SARS-CoV-2 RNA in 30 s, which was faster than TCCA1000 (10 min). Clearance of ORF1ab and N by TCCA500 required 10 and 60 min, respectively, whereas combination of TCCA500 with EA or PI destroyed ORF1ab and N faster at 30 s and 30 min, respectively. Conclusion The surroundings of patients with COVID-19 are contaminated by SARS-CoV-2 RNA. Effectiveness of disinfectants and combinations varies, N gene persists longer time than ORF1ab after some disinfection.

show abstract

“…During an infectious disease pandemic, interventional radiologists and staff members participating in the procedure should be familiar with the procedure as well as the spread of pathogens and disinfectants [ 33 ]. We found no cases of infection of staff members, including operators, or of other patients who underwent procedures after patients with COVID-19 due to droplet blocking and appropriate disinfection procedures.…”

Section: Discussionmentioning

confidence: 99%

The Role of Interventional Radiology and Management of an Angiography Suite in the Treatment of COVID-19 Patients: Single-Center, 2-Year Experience

Shim

Lee

2023

Medicina

View full text Add to dashboard Cite

Background and Objectives: Hospital angiography suites with negative-pressure ventilation facilities are challenging to equip. During the COVID-19 pandemic, we aimed to introduce interventional radiology procedures performed on COVID-19 patients and understand management of the angiography suite without a negative-pressure ventilation facility before and after the procedures to prevent the spread of infection. Materials and Methods: Between December 2020 and November 2022, 52 COVID-19 patients underwent interventional radiology procedures in an angiography suite, where no negative-pressure ventilation facility was installed. During the procedure, all staff members wore full personal protection equipment, and after the procedure for the COVID-19-positive patient was completed, the angiography suite was disinfected and entry to the angiography suite was prohibited for 1–3 h. In this angiography suite, procedures for COVID-19 patients and non-COVID-19 patients were performed. Results: A total of 61 interventional radiology procedures were performed in 52 patients with COVID-19. Of 52 patients, 21 underwent procedures under intubation and mechanical ventilation. All procedures were performed according to the guidelines set by the Infection Control Committee of our hospital. No major or minor complications were associated with the procedures. There were no cases of infection among staff members or other non-COVID-19 patients related to procedures on COVID-19 patients. Conclusions: Interventional radiology can play an important role in solving the complications of COVID-19 and the problems caused by patients’ underlying diseases. In addition, if accurate guidelines are followed, both COVID-19 and non-COVID-19 patients can undergo procedures in an angiography room without negative-pressure ventilation while preventing infection.

show abstract

Disinfectants against SARS-CoV-2: A Review

Cited by 34 publications

References 132 publications

Extending the Protection Ability and Life Cycle of Medical Masks through the Washing Process

Extending the Protection Ability and Life Cycle of Medical Masks through the Washing Process

Effectiveness of different disinfectants and combinations against SARS-CoV-2 nucleic acid in COVID-19 quarantine wards

The Role of Interventional Radiology and Management of an Angiography Suite in the Treatment of COVID-19 Patients: Single-Center, 2-Year Experience

Contact Info

Product

Resources

About