Disinfectants and Skin Antiseptics for Safe prophylaxis against COVID-19, Review of Literature.

Abstract

Coronavirus disease 2019 (COVID-19) is currently receiving the whole world's attention. It appeared first in Wuhan city of China and rapidly spread to the world, causing many mortalities and morbidities; the disease is mainly transmitted via respiratory droplets and has a long infectivity period of about 14 days. Science shows that the virus is also transmitted via the skin if the virus by any means finds its way and land on the skin surface. Infection occurs when touching the face, eyes, or nose with the hand after the virus has landed upon it. This is the main reason for the widespread usage of skin antiseptics and disinfectants. We included the most commonly used skin antiseptics, sterilizing methods, and disinfectants, such as household bleach, hydrogen peroxide gas plasma, Formaldehyde, Glutaraldehyde, Alcohol, Chlorohexidine, Povidone-iodine, Chloroxylenol, and alcohol-based hand sanitizer (e.g. Sterlelium). We will discuss their role in preventing acquired infection of COVID-19, as well as discussing the efficacy, costs, and side effects of different sterilizers, including general health hazards, as well as skin affection as irritant contact dermatitis, which is the commonest side effect. After conducting this work, we summarized the results & started sending them to our patients & medical personnel, and we observed 60% decrease in the cases of disinfectants induced allergic contact dermatitis /month compared to the previous two months.

Virucidal properties of new multifunctional fibrous N-halamine-immobilized styrene-divinylbenzene copolymers

“…The choice of these samples was based on the previously described features of Table 3. Virucidal activity (inactivation time) of synthesized polymers against poliovirus type-1 (1) .…”

“…Dichlorosulfonamide fibers and fabrics obviously have a higher concentration Table 4. Virucidal activity (inactivation time) of synthesized polymers against adenovirus type-5 (1) .…”

“…Recent events related to the COVID-19 pandemic have once again confirmed the vital need for the widespread implementation of measures to prevent infectious diseases. Materials and technologies that provide protection against infections of various etiologies certainly include antiseptics and disinfectants of various compositions, [1][2][3] devices for treating premises with proper types of radiation of sufficient power (ozone generators, UV-recirculators, etc. ), [4][5][6][7] as well as water and air treatment systems.…”

Broad-Purpose Solutions of N-Chlorotaurine: A Convenient Synthetic Approach and Comparative Evaluation of Stability and Antimicrobial Activity

“…Recent events related to the COVID-19 pandemic have demonstrated the vital need to develop new preparations and technologies for disinfection and antiseptic treatment of various surfaces and media as one of the most efective and afordable methods for preventing infectious diseases [1,2]. Special attention should be given to microbiocidal agents that can also be used for therapeutic purposes, for example, for the treatment of pneumonia or infected wounds.…”

Influence of the platinum surface state on the selectivity of the electrochemical synthesis of sodium hypochlorite

“…The COVID-19 pandemic has highlighted the importance of developing and widespread use of effective disinfection preparations and technologies as one of the most effective ways to prevent infectious diseases. 1,2 In this regard, active chlorine preparations (hypochlorous acid, hypochlorites, organic chloramines), which are among the most powerful microbicides, have received special attention. 3 Due to their pronounced oxidative activity, they effectively suppress microorganisms, 4 viruses 5 and prions, 6 and resistance to them is unlikely.…”