Disinfectants

Siebert, Jörg; Harke, H. P.

doi:10.1002/14356007.a08_551.pub2

Cited by 6 publications

(6 citation statements)

References 23 publications

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“…Afterwards the reuse criteria were verified. The devices were examined and reprogrammed to the factory default settings, after which they were submerged in a phenoxypropanol and benzalkonium chloride solution, rinsed with water, and air‐dried for 24 hours. Subsequently, they were cleaned with 70% ethanol and then sterilized with ethylene oxide.…”

Section: Methodsmentioning

confidence: 99%

Assessing the safety of implantable cardioverter‐defibrillator reuse—A retrospective case‐control study

Enache

Șoșdean

Macarie

et al. 2019

Pacing Clinical Electrophis

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Aims The safety of pacemaker reuse has been proven by numerous studies in the last two decades. With the exception of one research paper, the safety of reuse of implantable cardioverter‐defibrillators has not been properly investigated. Our aim was to establish whether resterilized implantable cardioverter‐defibrillators are as safe as new devices in relation to functionality and infection rates. Methods All the patients (n = 271) implanted with a new or a donated, used implantable cardioverter‐defibrillator (ICD) at the Institute of Cardiovascular Disease Timisoara Romania between January 2001 and December 2012 were included in the study. The patients had class I indication for ICD implantation. One hundred fifty‐seven patients received reused ICDs and 114 patients received new ICDs. Complications were defined as infections that required reintervention, device malfunction, and replacements due to untimely or unexpected battery depletion. Results Complications occurred in 4.38% of the patients in the new ICD group and in 1.91% of the reused ICD group. The difference was not considered statistically significant (odds ratio 0.28, 95% confidence interval 0.04‐1.82, P = .18). Conclusion According to our data, properly verified and resterilized ICDs are as safe as new devices, when risk of infection or malfunction rates are assessed. Due to the high costs of new ICDs, their safe reuse has profound humanitarian and financial implications.

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Section: Methodsmentioning

confidence: 99%

Assessing the safety of implantable cardioverter‐defibrillator reuse—A retrospective case‐control study

Enache

Șoșdean

Macarie

et al. 2019

Pacing Clinical Electrophis

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“…Menthol is highly soluble in many solvents but sparingly soluble in water (0.46 mg/mL at 298 K) . However, thymol is more soluble in water than menthol (0.98 mg/mL at 298 K) . Compared with DES-MD and DES-TD, the DES-MD-rich phase had much lower water contents than the DES-TD-rich phase.…”

Section: Resultsmentioning

confidence: 99%

Liquid–Liquid Equilibria for Pseudo-Ternary Systems of 1-Hydroxypropan-2-one + Water + Cyclic Terpene-Based Mixtures at 298.15 K

Choe

Song

2023

J. Chem. Eng. Data

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Herein, liquid−liquid equilibria (LLE) were investigated for pseudo-ternary systems comprising water + 1hydroxypropan-2-one + cyclic terpene-based mixtures at 298.15 K and 0.1 MPa. Menthol/levulinic acid-, menthol/dodecanoic acid-, menthol/thymol-, thymol/decanoic acid-, thymol/10-undecenoic acid-, and menthol/decanoic acid-based mixtures were prepared in 1:2, 2:1, 1:1, 1:1, 1:1, and 1:1 molar ratios, respectively, which are type V deep eutectic solvents (DESs). The pseudo-ternary system separation factors were determined. When decanoic acid was used as a hydrogen bond donor, the menthol-based DES exhibited a higher separation factor than the thymol-based DES. Among the pseudo-ternary systems, menthol-and decanoic-acid-based DESs exhibited the highest separation factor. A non-random two-liquid (NRTL) model was used to regress the LLE data. The Gibbsenergy-of-mixing (G M /RT) surface was topologically analyzed to determine the tie line consistency. The experimentally measured and NRTL-modeled tie lines were tangential to the G M /RT surface curve, indicating that the minimum Gibbs free energy of mixing was satisfied at equilibrium points.

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“…The acid functionality of the constituent DA in the DES appears to help increase the water intake. The higher solubility of Thy in water (∼0.98 g/L) as opposed to Men (∼0.46 g/L) may explain the higher water intake of Thy:DA DES as opposed to that of Men:DA DES. For Thy:Men DES, the water miscibility varies widely between 1.1 wt % (0.50:0.50) to 4.6 wt % (0.83:0.17).…”

Section: Resultsmentioning

confidence: 99%

Water Miscibility, Surface Tension, Density, and Dynamic Viscosity of Hydrophobic Deep Eutectic Solvents Composed of Capric Acid, Menthol, and Thymol

2022

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Deep eutectic solvents (DESs) are rapidly emerging as environmentally benign and viable alternatives not only to common organic solvents but to relatively toxic ionic liquids as well. By judicious selection of the constituents and subsequent variation in their composition, the key physicochemical properties of the DESs can be easily tailored for a specific application. Impact of variation in constituents as well as their composition on important physical properties of natural DESs (NADESs) prepared using a common fatty acid n-decanoic acid (DA) and two naturally occurring monoterpenoids, thymol (Thy) and L(−)-menthol (Men), is assessed. Specifically, water miscibility, surface tension, density, and dynamic viscosity of 17 different DESs of three combinations of constituents, Men:DA, Thy:DA, and Thy:Men in four, four, and nine compositions, respectively, are measured. The water intake by the DESs under ambient conditions varies from 0.6 to 2.7 mol·kg–1 offering a means to gauge their hydrophobicity. Water miscibility is relatively lower for Men:DA DESs and higher for Thy:DA DESs. Surface tension values are within 28.37 mN·m–1 to 31.14 mN·m–1 under ambient conditions; they are higher for the DESs with the Thy constituent and vary systematically with DES composition. The densities of all the DESs are lower than that of water and decrease linearly with increasing temperature. While density does not vary with composition for Men:DA, it is found to increase linearly with an increase in Thy mole fraction for Thy:DA and Thy:Men DESs. The dynamic viscosity of the DESs are relatively lower as compared to the common tetralkylammonium salt- and metal salt-based DESs, and exhibit strong constituent and composition dependence. Rather than the Arrhenius-type expression, the temperature-dependence of the dynamic viscosity better conforms to the Vogel–Fulcher–Tammann (VFT) model with activation energy of the viscous flow varying systematically with the constituent and composition. Reported physical properties and their dependence on constituents/composition of the NADESs will enhance their utility and help establish them as novel alternate media in science and technology.

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Disinfectants

Abstract: The article contains sections titled: 1. Introduction 2. Definitions … Show more

Cited by 6 publications

References 23 publications

Assessing the safety of implantable cardioverter‐defibrillator reuse—A retrospective case‐control study

Assessing the safety of implantable cardioverter‐defibrillator reuse—A retrospective case‐control study

Liquid–Liquid Equilibria for Pseudo-Ternary Systems of 1-Hydroxypropan-2-one + Water + Cyclic Terpene-Based Mixtures at 298.15 K

Water Miscibility, Surface Tension, Density, and Dynamic Viscosity of Hydrophobic Deep Eutectic Solvents Composed of Capric Acid, Menthol, and Thymol

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