Dislipidemia entre crianças e adolescentes de Pernambuco

Abstract

Objective: To describe the prevalence of dyslipidemia and overweight among children and adolescents in the state of Pernambuco, Brazil. Methods:During clinical evaluation, a questionnaire was completed through interviews with parents and included personal details of the children and adolescents. An exclusion criterion was personal or parental history of diabetes or coronary artery disease (CAD). Blood samples were collected from subjects who had been fasting for 12 hours, and the following evaluations were performed using enzymatic methods: serum Total Cholesterol, LDL-Cholesterol, HDL-Cholesterol and Triglycerides. Data were analyzed using the SPSS 11.5 statistical package including Student's t test and Fisher's exact test. Results:Of the 414 children and adolescents analyzed in the present study, about 30% presented an atherogenic lipid profile, characterized by higher levels of Triglyceride, Total and LDL-Cholesterol. The prevalence of overweight in this sample from Pernambuco was 4%. Girls had higher levels of Triglycerides and Total Cholesterol than boys. Children and adolescents presented the same values of lipid on blood that is not expected for children in this phase of development. Conclusion:In the present population, an unfavorable lipid profile among children and adolescents from Pernambuco suggests that programs targeting the prevention of cardiovascular disease and obesity must begin early in life.

Perfil lipídico em escolares de Recife - PE

“…The mean levels of lipids and lipoproteins obtained from the schoolchildren from the public schools in Recife are lower than the ones reported by other studies 1,5,6,10,30 , except for the ones reported by Moura et al 5 and Franca and Alves 1 in which TG levels were slightly lower. Although the studies on the influence of the socioeconomic level on the lipid profile are not consensual, studies carried out in Brazil show lower means of TC, TG and LDL in the group from the lowest socioeconomic class 6,7,26 .…”

“…Other studies have also demonstrated higher percentages of increased TC levels, when considering values > 170 mg/ dl 1,5,6 . On the other hand, our findings are in accordance with those by Scherr et al 7 , who found a lower magnitude of hypercholesterolemia among schoolchildren from public/ philanthropic schools (14%).…”

“…Evidence has demonstrated that high levels of total cholesterol (TC), LDL-cholesterol (LDL-c) and triglycerides (TG), as well as decreased levels of HDL-cholesterol (HDL-c) are related to a higher incidence of hypertension and atherosclerotic disease 1 .…”

Prevalence of Child Dyslipidemia in a Laboratory of Vale Do Sinos - Rs

“…Como resultado do aumento lipídico circulante há a formação de placas lipídicas ou ateromas, as quais se depositam na parede arterial, obstruindo a luz dos vasos sanguíne-os e está relacionada com maior incidência de doença aterosclerótica. (3) Os fatores de risco cardiovasculares são considerados graves problemas de saúde pública e quando acompanhados de obesidade se tornam ainda mais preocupantes. A ausência de sinais e sintomas relacionados às alterações lipídicas faz com que seu diagnóstico seja realizado através de exames bioquímicos, pela determinação do perfil lipídico, onde é necessária a dosagem de colesterol total (CT), colesterol de baixa densidade (LDL), triglicerídeos (TG) e colesterol de alta densidade (HDL).…”

Effects of splenic allograft in lipid profile of non-splenectomized rats: the immune and metabolic role of the "double spleen"

“…yslipidemia is characterized by abnormal concentrations of lipids and lipoproteins in the blood and is responsible for high morbidity and mortality in the general population due to high blood pressure and, in particular, to atherosclerotic diseases 1 . The Spleen, which stands out for the filtration and hematopoietic functions, also participates in metabolic control 2 .…”