Disorders of the Endocrine System

Reed, Stephen M.; Bayly, W. M.; Sellon, Debra C.

doi:10.1016/b978-0-323-44329-6.00016-4

Cited by 22 publications

(14 citation statements)

References 805 publications

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“…Though most of the previous studies evaluating metabolic dysfunctions have been focused on obese animals, lean horses can also develop metabolic dysregulation and insulin dysfunction [ 37 ]. Available data are very limited; some possible explanations, however, are proposed, mostly relying on the altered hepatic response of affected lean horses to certain nutrients and increased production of cortisol within adipose tissue [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

Clustering and Correlations amongst NEFA, Selected Adipokines and Morphological Traits—New Insights into Equine Metabolic Syndrome

Daradics

Niculae

Crecan

et al. 2022

Animals

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Obesity is a common feature in horses suffering from metabolic syndrome. While adipokines involvement as biomarkers is better established in human pathology, little data are available on horses. This study aimed to investigate the possible association and relationship between selected metabolic parameters and morphological traits in equine metabolic syndrome. Adiposity was evaluated using body condition score (BCS) and cresty neck score (CNS). Plasma levels of total cholesterol, insulin, NEFA, and adipokines (omentin and chemerin) were determined using enzyme-linked immunosorbent assays. Spearman correlation, univariate linear regression analysis and hierarchical clustering were performed. Significant positive correlations were observed between NEFA and bodyweight (r = 0.322; p = 0.006), BCS (r = 0.295; p = 0.013), and CNS (r = 0.267; p = 0.024), total cholesterol and bodyweight (r = 0.262; p = 0.027), and omentin and CNS (r = 0.234; p = 0.049). Cluster analysis supported these results and provided more details on the relationships between studied variables within and between the four resulting groups. These findings highlight NEFA, chemerin, and omentin as valuable biomarkers that could be further analyzed in other horse breeds for a better understanding of equine metabolic pathology.

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Section: Discussionmentioning

confidence: 99%

Clustering and Correlations amongst NEFA, Selected Adipokines and Morphological Traits—New Insights into Equine Metabolic Syndrome

Daradics

Niculae

Crecan

et al. 2022

Animals

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“…Dazu zählen z. B. Pneumocystis jirovecii, Cryptococcus neoformans oder Mykosen (Aspergillus, Candida), auch wenn diese beim Pferd sicherlich selten bis sehr selten sind [7,17].…”

Section: Opportunistische Infektionenunclassified

“…Dies betrifft unter anderem den sog. "granular cell tumor" des Pferdes, aber natürlich auch Melanome oder Plattenepithelkarzinom-Metastasen [17].…”

Section: Neoplasienunclassified

TBS- und BAL-Zytologie – Es ist nicht immer Equines Asthma

Schwarz¹,

Kühn²

2021

pferde spiegel

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“…Atopic dermatitis (AD) is a heritable condition characterized by an abnormal IgE‐mediated immune response to environmental allergens . Affected horses may be pruritic and develop secondary lesions such as alopecia, crusts, excoriation, erythema and urticaria; with the face, pinnae, ventrum and legs commonly affected . Depending on the environment and causative allergens, clinical signs may be seasonal or non‐seasonal in nature .…”

Section: Introductionmentioning

confidence: 99%

“…Affected horses may be pruritic and develop secondary lesions such as alopecia, crusts, excoriation, erythema and urticaria; with the face, pinnae, ventrum and legs commonly affected . Depending on the environment and causative allergens, clinical signs may be seasonal or non‐seasonal in nature . Severely affected horses may even have loss of body condition or behavioural changes secondary to the discomfort associated with unrelenting pruritus.…”

Section: Introductionmentioning

confidence: 99%