Disparities in Management Patterns and Outcomes of Patients With Non–ST-Elevation Acute Coronary Syndrome With and Without a History of Cerebrovascular Disease

Lee, Tony C.; Goodman, Shaun G.; Yan, Raymond T.; Grondin, François; Welsh, Robert C.; Rose, Barry; Gyenes, Gábor; Zimmerman, Rodney H.; Brossoit, R; Saposnik, Gustavo; Graham, John

doi:10.1016/j.amjcard.2009.12.005

Cited by 27 publications

(20 citation statements)

References 31 publications

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“…Both stroke and advanced heart failure are well-established predictors of poor outcome at follow-up. [21][22][23] Consistently with previous studies, we also found chronic kidney disease to be independently associated with worse outcomes in patients undergoing TAVI. 10,24 Multiple factors may account for the mechanism linking chronic kidney disease and late mortality in TAVI patients.…”

Section: Tamburino Et Al Transcatheter Aortic Valve Implantation 305supporting

confidence: 80%

Incidence and Predictors of Early and Late Mortality After Transcatheter Aortic Valve Implantation in 663 Patients With Severe Aortic Stenosis

et al. 2011

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Background-There is a lack of information on the incidence and predictors of early mortality at 30 days and late mortality between 30 days and 1 year after transcatheter aortic valve implantation (TAVI) with the self-expanding CoreValve Revalving prosthesis. Methods and Results-A total of 663 consecutive patients (mean age 81.0Ϯ7.3 years) underwent TAVI with the third generation 18-Fr CoreValve device in 14 centers. Procedural success and intraprocedural mortality were 98% and 0.9%, respectively. The cumulative incidences of mortality were 5.4% at 30 days, 12.2% at 6 months, and 15.0% at 1 year.

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Section: Tamburino Et Al Transcatheter Aortic Valve Implantation 305supporting

confidence: 80%

Incidence and Predictors of Early and Late Mortality After Transcatheter Aortic Valve Implantation in 663 Patients With Severe Aortic Stenosis

et al. 2011

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“…In addition, patients with higher Global Registry of Acute Coronary Events (GRACE) scores (and higher risk of hospital mortality) were less likely to receive an invasive management strategy. Previous publications from large prospective registries have reported similar findings 7 , 8 . This may be explained by factors such as advanced age and renal failure, which contribute to the GRACE score but also reduce the likelihood of acute intervention 3 .…”

mentioning

confidence: 53%

The SNAPSHOT ACS study: getting the big picture on acute coronary syndrome

Macdonald

Newton

Davidson

2013

Medical Journal of Australia

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“…This is consistent with some of the previous reports. Other independent risk factors previously reported in other reports include prior or in-hospital CABG, renal impairment, low body weight and elevated admission heart rate [11-32]. These variability in findings may be attributed to several factors including patients’ population, ethnicities, use of thrombolytic therapy versus primary percuatenous revascularization therapy and underscore the need of further international studies that include adequate representations of female gender and various ethnicities [33].…”

Section: Discussionmentioning

confidence: 95%

Immediate and one-year outcome of patients presenting with Acute Coronary Syndrome complicated by stroke: Findings from the 2ndGulf Registry of Acute Coronary Events (Gulf RACE-2)

Suwaidi

Habib

Asaad

et al. 2012

BMC Cardiovasc Disord

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BackgroundStroke is a potential complication of acute coronary syndrome (ACS). The aim of this study was to identify the prevalence, risk factors predisposing to stroke, in-hospital and 1-year mortality among patients presenting with ACS in the Middle East.MethodsFor a period of 9 months in 2008 to 2009, 7,930 consecutive ACS patients were enrolled from 65 hospitals in 6 Middle East countries.ResultsThe prevalence of in-hospital stroke following ACS was 0.70%. Most cases were ST segment elevation MI-related (STEMI) and ischemic stroke in nature. Patients with in-hospital stroke were 5 years older than patients without stroke and were more likely to have hypertension (66% vs. 47.6%, P = 0.001). There were no differences between the two groups in regards to gender, other cardiovascular risk factors, or prior cardiovascular disease. Patients with stroke were more likely to present with atypical symptoms, advanced Killip class and less likely to be treated with evidence-based therapies. Independent predictors of stroke were hypertension, advanced killip class, ACS type –STEMI and cardiogenic shock. Stroke was associated with increased risk of in-hospital (39.3% vs. 4.3%) and one-year mortality (52% vs. 12.3%).ConclusionThere is low incidence of in-hospital stroke in Middle-Eastern patients presenting with ACS but with very high in-hospital and one-year mortality rates. Stroke patients were less likely to be appropriately treated with evidence-based therapy. Future work should be focused on reducing the risk and improving the outcome of this devastating complication.

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Disparities in Management Patterns and Outcomes of Patients With Non–ST-Elevation Acute Coronary Syndrome With and Without a History of Cerebrovascular Disease

Cited by 27 publications

References 31 publications

Incidence and Predictors of Early and Late Mortality After Transcatheter Aortic Valve Implantation in 663 Patients With Severe Aortic Stenosis

Incidence and Predictors of Early and Late Mortality After Transcatheter Aortic Valve Implantation in 663 Patients With Severe Aortic Stenosis

The SNAPSHOT ACS study: getting the big picture on acute coronary syndrome

Immediate and one-year outcome of patients presenting with Acute Coronary Syndrome complicated by stroke: Findings from the 2ndGulf Registry of Acute Coronary Events (Gulf RACE-2)

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