Disparity of motoneurone and muscle differentiation following spinal transection in the kitten.

Gallego, Roberto; Huizar, P; Kudo, Norio; Kuno, Motoý

doi:10.1113/jphysiol.1978.sp012420

Cited by 43 publications

(29 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Accordingly, fast activity patterns are not considered to play a significant role in determining fast twitch properties, 19 and the fast speed of muscles crossreinnervated with a fast nerve is attributed to the absence of tonic activity rather than the high frequency activity of fast motoneurones. 20 Our results suggest a different view. Also we find that the soleus can be made considerably faster merely by reducing the amount of activity, particularly at low stimulation frequencies (Fig.…”

Section: Discussioncontrasting

confidence: 49%

The response of denervated muscle to long-term electrical stimulation

et al. 2014

View full text Add to dashboard Cite

Section: Discussioncontrasting

confidence: 49%

The response of denervated muscle to long-term electrical stimulation

et al. 2014

View full text Add to dashboard Cite

“…It should be noted that motoneurones destined to be fast are then developed into a less excitable state by the reduction in input resistance, due to resistivity, size and geometry changes, and possibly also by other intrinsic differences making F motoneurones less excitable than S motoneurones (Burke & Nelson, 1971;Fleshman, Munson, Sypert & Friedman, 1981;Kernell & Monster, 1981;Gustaffson & Pinter, 1984b). As suggested by the results of Gallego, Huizar, Kudo & Kuno (1978), a quiescent motoneurone would lead to a speeding of its muscle unit from the slow contraction present at birth. One may then surmise that a post-natal differentiation into type F motoneurones, leading into a developing decrease in their excitability and a reduction in their motor activity, would result in the observed muscle unit speeding (cf.…”

Section: Effects Of Axotomy Discussionmentioning

confidence: 94%

“…One may then surmise that a post-natal differentiation into type F motoneurones, leading into a developing decrease in their excitability and a reduction in their motor activity, would result in the observed muscle unit speeding (cf. Gallego et al 1978). On the other hand, the relatively more excitable type S motoneurones would be more active, which would, as discussed by Gallego et al (1978), counteract the muscle unit speeding.…”

Section: Effects Of Axotomy Discussionmentioning

confidence: 99%

“…Gallego et al 1978). On the other hand, the relatively more excitable type S motoneurones would be more active, which would, as discussed by Gallego et al (1978), counteract the muscle unit speeding. It should be recognized that this scheme whereby motoneurone differentiation leads to muscle differentiation remains speculative since it is not known whether kitten motoneurones actually are all slow at birth, if differentiation of motoneurone excitability properties precedes muscle differentiation or if such a motoneurone differentiation leads to the presumed change in firing activity.…”

Section: Effects Of Axotomy Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of axotomy on the distribution of passive electrical properties of cat motoneurones.

Gustafsson¹,

Pinter²

1984

The Journal of Physiology

View full text Add to dashboard Cite

SUMMARY1. Previously obtained experimental results concerning the effect of axotomy on motoneurone passive electrical properties have been re-analysed. As shown earlier, axotomy causes an average increase of motoneurone input resistance, membrane time constant and after-hyperpolarization duration.2. The present analysis suggests that the increased input resistance is related to a higher specific membrane resistivity, a decreased cell size and an altered dendritic geometry. The results also suggest that the change takes place only in neurones projecting to fast-twitch muscle units and produces in them passive electrical properties normally exhibited only by motoneurones projecting to slow-twitch units.3. Based on the notion that axotomy causes a dedifferentiationn' of motoneurone properties, the present results might be taken to indicate that undifferentiated motoneurones are slow in character.4. A possible scheme in which a post-natal differentiation ofmotoneurone properties may lead to muscle differentiation is discussed.

show abstract

“…To the best of our knowledge, no studies have adequately demonstrated the relationship between different strengths of the muscle and pathological changes in the MTJ avulsion injuries over time. However, an experimental study of muscle injuries by Gallego et al [24] showed that the ruptured muscle would be atrophied because it lost the immediate conservative treatment for 1 case of EDC tendon injury. length-tension relationship, which is one of the main determinants of disuse atrophy.…”

Section: Discussionmentioning

confidence: 99%

Could immediate treatment change the management method of digital tendon musculotendinous junction avulsion?: a systematic review

Park

2017

Yeungnam Univ J Med

View full text Add to dashboard Cite

Background:We conducted a systematic review of the literature to investigate the correlation between the interval to treatment and management of tendon avulsion ruptures in the musculotendinous junction (MTJ) of the forearm. Methods: A thorough literatures search for studies of tendon avulsion injuries at the forearm was conducted using PubMed, MEDLINE, CINAHL, and Cochrane databases in accordance with the PRISMA guidelines. In total, five case series and 15 case reports accounting for 87 injured tendons involving 60 patients were selected for the analysis. Results: Twenty-six patients had 44 tendon injuries associated with avulsion amputations, 31 patients had 38 tendon ruptures associated with closed avulsion injuries and three patients had five tendon ruptures associated with open avulsion injuries. Eighteen of the 49 (37%) patients were immediately treated for tendon ruptures and one of the 32 (3%) tendon ruptures treated via elective surgery was directly repaired. Additionally, 18 of the 30 (60%) tendons were directly repaired and 12 of the 30 (40%) tendons were transferred or side-to-side repaired in the immediately treated series. In contrast, one of the 28 (4%) tendon ruptures were directly repaired and 27 of the 28 (96%) tendons were transferred or side-to-side repaired in the electively treated series. Conclusion: In managing digital tendon avulsions at the MTJ, an immediate treatment could provide an opportunity to repair the ruptured tendon directly to the muscle.

show abstract

Disparity of motoneurone and muscle differentiation following spinal transection in the kitten.

Cited by 43 publications

References 27 publications

The response of denervated muscle to long-term electrical stimulation

The response of denervated muscle to long-term electrical stimulation

Effects of axotomy on the distribution of passive electrical properties of cat motoneurones.

Could immediate treatment change the management method of digital tendon musculotendinous junction avulsion?: a systematic review

Contact Info

Product

Resources

About