Disruption and Overexpression of the Gene Encoding ACC (1-Aminocyclopropane-1-Carboxylic Acid) Deaminase in Soil-Borne Fungal Pathogen <i>Verticillium dahliae</i> Revealed the Role of ACC as a Potential Regulator of Virulence and Plant Defense

Tsolakidou, Maria-Dimitra; Pantelides, Iakovos S.; Tzima, Aliki; Kang, Seogchan; Paplomatas, Epaminondas J.; Tsaltas, Dimitrios

doi:10.1094/mpmi-07-18-0203-r

Cited by 36 publications

(35 citation statements)

References 75 publications

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“…Pathogenic microbes can employ similar strategies with beneficial microbes to colonize their hosts. For example, overexpression of ACC deaminase gene in V. dahliae significantly lowered ACC levels in the roots of infected tomato plants and increased both its virulence and the fungal biomass in the vascular tissues of plants (Tsolakidou et al, 2019b). Therefore, future studies need to address how functions shared by both beneficial and pathogenic microbes are perceived by the plants and how plants can maintain a balance in the rhizosphere.…”

Section: Rhizosphere Microbiome As a Source Of Benefits For The Plantmentioning

confidence: 99%

Modulation of the Root Microbiome by Plant Molecules: The Basis for Targeted Disease Suppression and Plant Growth Promotion

et al. 2020

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Plants host a mesmerizing diversity of microbes inside and around their roots, known as the microbiome. The microbiome is composed mostly of fungi, bacteria, oomycetes, and archaea that can be either pathogenic or beneficial for plant health and fitness. To grow healthy, plants need to surveil soil niches around the roots for the detection of pathogenic microbes, and in parallel maximize the services of beneficial microbes in nutrients uptake and growth promotion. Plants employ a palette of mechanisms to modulate their microbiome including structural modifications, the exudation of secondary metabolites and the coordinated action of different defence responses. Here, we review the current understanding on the composition and activity of the root microbiome and how different plant molecules can shape the structure of the root-associated microbial communities. Examples are given on interactions that occur in the rhizosphere between plants and soilborne fungi. We also present some well-established examples of microbiome harnessing to highlight how plants can maximize their fitness by selecting their microbiome. Understanding how plants manipulate their microbiome can aid in the design of next-generation microbial inoculants for targeted disease suppression and enhanced plant growth.

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Section: Rhizosphere Microbiome As a Source Of Benefits For The Plantmentioning

confidence: 99%

Modulation of the Root Microbiome by Plant Molecules: The Basis for Targeted Disease Suppression and Plant Growth Promotion

et al. 2020

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“…ACC is required for the division of the guard mother cell (GMC) likely via the regulation of the indicated cell cycle regulators (Shin et al, 2014). (C) Overexpression of the ACC deaminase from the fungal pathogen of tomato, Verticillium dahliae, enhances its virulence, and pre-treatment of tomato plants with ACC reduced the symptoms of V. dahliae infection even in ethylene-insensitive mutants (Tsolakidou et al, 2019). (D) ACC is involved in cell wall signaling regulating anisotropic elongation of root cells (Xu et al, 2008;Tsang et al, 2011).…”

Section: Acc In Plant Development and Beyondmentioning

confidence: 99%

“…The fungal pathogen, Verticillium dahliae is a soil-borne pathogen of many plant species, causing vascular wilt disease. Tsolakidou et al (2019) found that genetic modulation of ACC levels in V. dahliae affected its microsclerotia development and hyphae growth. Overexpression of ACC deaminase in V. dahliae led to increased virulence on tomato and eggplant, including enhanced wilting and greater fungal growth.…”

Section: Polko and Kiebermentioning

confidence: 99%

1-Aminocyclopropane 1-Carboxylic Acid and Its Emerging Role as an Ethylene-Independent Growth Regulator

Polko

Kieber

2019

Front. Plant Sci.

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1-Aminocyclopropane 1-carboxylic acid (ACC) is the direct precursor of the plant hormone ethylene. ACC is synthesized from S-adenosyl-L-methionine (SAM) by ACC synthases (ACSs) and subsequently oxidized to ethylene by ACC oxidases (ACOs). Exogenous ACC application has been used as a proxy for ethylene in numerous studies as it is readily converted by nearly all plant tissues to ethylene. However, in recent years, a growing body of evidence suggests that ACC plays a signaling role independent of the biosynthesis. In this review, we briefly summarize our current knowledge of ACC as an ethylene precursor, and present new findings with regards to the post-translational modifications of ACS proteins and to ACC transport. We also summarize the role of ACC in regulating plant development, and its involvement in cell wall signaling, guard mother cell division, and pathogen virulence.

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“…Tomato lines with a mutation in this receptor present an impaired ethylene perception, due to a single amino acid change in the ethylene-binding domain (Pro36Leu) [19][20][21]. These mutants, named Never ripe (Nr), have been used to study the relationship between ethylene signaling and disease development in different pathogens [22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

Ethylene is Involved in Symptom Development and Ribosomal Stress of Tomato Plants upon Citrus Exocortis Viroid Infection

Prol

López-Gresa

Rodrigo

et al. 2020

Plants

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Citrus exocortis viroid (CEVd) is known to cause different symptoms in citrus trees, and its mechanism of infection has been studied in tomato as an experimental host, producing ribosomal stress on these plants. Some of the symptoms caused by CEVd in tomato plants resemble those produced by the phytohormone ethylene. The present study is focused on elucidating the relationship between CEVd infection and ethylene on disease development. To this purpose, the ethylene insensitive Never ripe (Nr) tomato mutants were infected with CEVd, and several aspects such as susceptibility to infection, defensive response, ethylene biosynthesis and ribosomal stress were studied. Phenotypic characterization revealed higher susceptibility to CEVd in these mutants, which correlated with higher expression levels of both defense and ethylene biosynthesis genes, as well as the ribosomal stress marker SlNAC082. In addition, Northern blotting revealed compromised ribosome biogenesis in all CEVd infected plants, particularly in Nr mutants. Our results indicate a higher ethylene biosynthesis in Nr mutants and suggest an important role of this phytohormone in disease development and ribosomal stress caused by viroid infection.

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Disruption and Overexpression of the Gene Encoding ACC (1-Aminocyclopropane-1-Carboxylic Acid) Deaminase in Soil-Borne Fungal Pathogen Verticillium dahliae Revealed the Role of ACC as a Potential Regulator of Virulence and Plant Defense

Cited by 36 publications

References 75 publications

Modulation of the Root Microbiome by Plant Molecules: The Basis for Targeted Disease Suppression and Plant Growth Promotion

Modulation of the Root Microbiome by Plant Molecules: The Basis for Targeted Disease Suppression and Plant Growth Promotion

1-Aminocyclopropane 1-Carboxylic Acid and Its Emerging Role as an Ethylene-Independent Growth Regulator

Ethylene is Involved in Symptom Development and Ribosomal Stress of Tomato Plants upon Citrus Exocortis Viroid Infection

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