Disseminated aspergillosis following radiation therapy for medulloblastoma

Hamilton, P. J. S.; Darbyshire, P. J.; McKeever, Patrick J.; Oakhill, A.

doi:10.1136/pgmj.61.714.345

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…The significance of this discovery is highlighted by several reports, over the years, of A. fumigatus infections in radiation therapy patients. [12][13][14][15] This finding lends additional support for a presumptive hypothesis that (1) dormant bacterial/fungal spores facilitate attachment to thermoplastic mask surfaces and that (2) spores enable these microbes to survive for an extended time interval.…”

Section: Discussionsupporting

confidence: 61%

Two Bacillus isolates recovered from a radiation therapy facility differ greatly in their ability to attach to four immobilization masks

Ravine

2020

Journal of Medical Imaging and Radiation Sciences

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Section: Discussionsupporting

confidence: 61%

Two Bacillus isolates recovered from a radiation therapy facility differ greatly in their ability to attach to four immobilization masks

Ravine

2020

Journal of Medical Imaging and Radiation Sciences

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“…В литературе описаны единичные клинические случаи тяжелого течения ИМ при солидных новообразованиях, подчеркнуты трудности дифференциальной диагностики и необходимость проведения агрессивной антимикотической терапии [27,43].…”

Section: автор источникunclassified

Invasive aspergillosis in children and adolescents with solid tumors: clinical cases and registry analysis

et al. 2019

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We presented two cases of invasive aspergillosis (IA) in children with solid tumors, data of IA patients register, and a literature review. In theregister of patients with IA (1997–2018), we found 57 patients with IA from 0 to 18 years. It was established that the number of patients with solid tumors was 15.7 %. Background diseases were: central nervous system tumors – 33.5 %, neuroblastoma – 33.5 %, osteosarcoma – 11.0 %, Wilms tumor – 11.0 %, hemangioblastoma – 11.0 %. Chemotherapy-induced neutropenia was reported in 100 % of IA cases in children and adolescents with solid tumors. The additional risk factors were treatment in intensive care unit – 22.2 %, high-dose chemotherapy with autologous hematopoietic stem cell transplantation – 22.2 %, concomitant bacterial infection – 33.0 %. Surgical intervention for the underlying disease was performed in 77.7 % of patients. The most common clinical site of IA was the lungs – 88.9 %. The predominant clinical sign was fever – 66.7 %, cough and respiratory failure were seen less frequently – 33.4 % and33.4 %, respectively. The etiologicalagents of IA were Aspergillus fumigatus – 33.3 %, Aspergillus nidulans – 33.3 % and Aspergillus ustus – 33.3 %. 88.9 % of patients received antimycotic therapy, voriconazole predominantly – 66.7 %. Combination therapy was used in 33.3 % of patients. The overall 12-week survival in children and adolescents with IA in case of solid tumors was 77.8 %.

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Examining properties influencing infectious microbe associations with surfaces of four different thermoplastic radiation therapy masks

Ravine

2021

Journal of Medical Imaging and Radiation Sciences

View full text Add to dashboard Cite

Disseminated aspergillosis following radiation therapy for medulloblastoma

Cited by 3 publications

References 7 publications

Two Bacillus isolates recovered from a radiation therapy facility differ greatly in their ability to attach to four immobilization masks

Two Bacillus isolates recovered from a radiation therapy facility differ greatly in their ability to attach to four immobilization masks

Invasive aspergillosis in children and adolescents with solid tumors: clinical cases and registry analysis

Examining properties influencing infectious microbe associations with surfaces of four different thermoplastic radiation therapy masks

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