Disseminated fusariosis in immunocompromised patients

Disseminated fusariosis with cutaneous involvement in hematologic malignancies: report of six cases with high mortality rate

“… 6 The risk factors for invasive fusariosis are neutropenia, deficient cellular immunity, induction chemotherapy for leukemia, hematopoietic cell transplantation, and graft-versus-host disease-the same risk factors that patients of this series possessed. 1 , 2 , 5 In these cases, skin and nails must be examined for sites of infection that can serve as gateway for system dissemination. 1 Cutaneous involvement can be an important diagnostic clue, since the skin lesions are observable in the early stages of the disease and can even precede positive hemocultures.…”

“…Fusarium spp. are the second most frequent invasive fungal infection in patients with hematologic neoplasms-after only Aspergillus spp.-but are the most common agents of fungemia with skin manifestations (70% to 75% of patients present cutaneous lesions) 4 , 5 …”

Disseminated Fusariosis in a Pediatric Population

“…are often resistant to antifungal therapy, and infections have a mortality rate of 60% to 80% (4–6). Several articles have also suggested that the degree of neutropenia can adversely affect outcomes (7,8).…”

Hyalohyphomycosis (Fusariosis): Atypical Presentation in an Immunocompetent Individual Responding to Itraconazole

“…[ 1 ] Cutaneous fusariosis generally presents as multiple painful, erythematous papules, or nodules with or without central necrosis, onychomycosis, and periungual cellulitis. [ 2 ] We present an atypical case of fusariosis, in the form of multiple large cystic swellings, psoriasiform plaques, and palmoplantar keratoderma which showed complete resolution with itraconazole.…”