Disseminated superficial actinic porokeratosis (DSAP)

Mibelli revisited: A case of type 2 segmental porokeratosis from 1893

“….but easily felt on account of their sharply circumscribed roughness''. These facial lesions would be compatible with a diagnosis of DSAP, 8 but the size of the other lesions is more suggestive of PM. 9 This diagnosis is supported by the fact that ''the same skin affection'' was present in an older brother since the age of 8 years and in a younger sister since the age of 10 years, which virtually excludes DSAP.…”

Bullous and Pruritic Variant of Disseminated Superficial Actinic Porokeratosis: Successful Treatment with Grenz Rays

“…Despite the fact that he has not been extensively exposed to the sun in the last 20 years, DSAP spread and extended not only to light-exposed areas but also to covered areas of the trunk. His major complaint was pruritus, which seems not to be uncommon according to the literature [12, 13, 17, 18]. Interestingly, the patient had not only the typical lesions of porokeratosis with the characteristic histopathological features [13, 19], but also a bullous eruption, especially on the legs, without evidence of genuine bullous disease.…”

“…DSAP is an autosomal-dominant genodermatosis with some sporadic cases, develops mainly during the third and fourth decades of life [12]and is usually asymptomatic and insidious at the onset. Pruritus is not unusual.…”

Scaly Atrophic Lesions Both Scattered and in Linear Arrays

“…It is characterized by scattered 5-to 10-mm lesions that tend to be bilateral, symmetric, and confined to sunexposed areas. 3 The characteristic clinical findings may be quite subtle, with a barely perceptible kera¬ totic rim. Analogously, the histopathologic findings may show a cornoid lamella smaller than that seen in solitary porokeratosis.…”