Dissociation of body weight and lean body mass during cancer chemotherapy

Graaf, Siebold S.N. de; Roest, Wilma P Meeuwsen-Van Der; Koops, Heimen Schraffordt; Zijlstra, W. G.

doi:10.1016/0277-5379(87)90270-7

Cited by 9 publications

(2 citation statements)

References 16 publications

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“…However, a good correlation was reported between changes in arm muscle area and changes in body cell mass. De Graaf et al also reported a dissociation of body weight and lean body mass in children and adolescents receiving chemotherapy for cancer and suggested the use of deuterium oxide dilution techniques for a serial monitoring of lean body mass in this group of patients (de Graaf et al, 1987). More recently, bioelectrical impedance was validated for estimating free fat mass in a group of 56 children and young adults and was found to give reliable estimates compared with isotope dilution techniques (Suprasongsin et al, 1995).…”

Section: Nutritional Assessmentmentioning

confidence: 99%

Nutritional considerations in children undergoing bone marrow transplantation

Papadopoulou

1998

Eur J Clin Nutr

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Bone marrow transplantation is often associated with multiple organ failure which is usually reversible. Oral mucositis and dysphagia, vomiting, diarrhoea, protein losing enteropathy, transient exocrine pancreatic impairment, hypoalbuminaemia, biochemical trace element and mineral de®ciencies are all common following transplantation and have profound nutritional consequences. Malnutrition affects negatively the clinical outcome. Nutritional support is provided to malnourished patients and those who suffer deterioration in nutritional status despite the provision of dietetic counselling. Only a few randomised studies comparing enteral with parenteral nutrition after transplant exist. Both enteral tube feeding (in the absence of mucositis) and parenteral nutrition are effective in maintaining nutritional status. However, enteral nutrition is associated with a better nutritional response and fewer complications than parenteral. With existing enteral and parenteral nutrition regimens close monitoring of trace element and mineral status is required.

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Section: Nutritional Assessmentmentioning

confidence: 99%

Nutritional considerations in children undergoing bone marrow transplantation

Papadopoulou

1998

Eur J Clin Nutr

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“…The isotope dilution technique is established in >70 LMICs and has been used to understand body composition in healthy children and those with acute malnutrition, as well as a reference to validate simple body composition techniques. There have been several studies done in cancer patients using deuterium dilution in HICs to determine body composition ( 33 , 34 ). However, there is only 1 known study in Mexico that used deuterium dilution to assess body composition in children with cancer ( 35 ).…”

Section: Current Status Of Knowledgementioning

confidence: 99%

Perspective: Creating the Evidence Base for Nutritional Support in Childhood Cancer in Low- and Middle-Income Countries: Priorities for Body Composition Research

Murphy‐Alford

Prasad

Slone

et al. 2020

Advances in Nutrition

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There is a striking disparity in survival rates for children in low- and middle-income countries (LMICs) compared with high-income countries (HICs). Many of the contributing factors are preventable, including the comorbidity of malnutrition. There are emerging data that malnutrition, as reflected in body composition changes, impacts survival of cancer. However, not enough priority is given to nutrition management of children with cancer, particularly in LMICs. The primary purpose of this article is to review the current knowledge on childhood cancer and body composition in LMICs and identify priorities for future research into the interlinking associations between cancer, body composition, and clinical outcomes for childhood cancer patients. Evidence will ensure feasible and effective nutrition management is prioritized in childhood cancer centers in LMICs and contribute to improving outcomes for children with cancer.

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Hyperalimentation in autologous bone marrow transplantation for solid tumors. Comparison of total parenteralVersus partial parenteral plus enteral nutrition

Mulder¹,

Bouman²,

Gietema³

et al. 1989

Cancer

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Recipients of autologous bone marrow transplantation (ABMT) for solid tumors need nutritional support to maintain their body weight (BW). Severe BW-reduction (9.9%) was noticed retrospectively in ten ABMT patients fed orally, despite intensive counseling or occasional tube feeding. A prospective, ran-domized study of hyperalimentation (25 g nitrogen (N) and 3400 nonprotein kilocalories) with total par-enteral nutrition (TPN) or partial parenteral plus enteral nutrition by tube feeding (PPN/EN) was done in 22 patients. Nutritional assessment included balance measurements of N, Na, K, CI, P, Ca, Mg, Cu, and Zn, and serial measurements of BW, serum albumin, prealbumin, and transferrin. Both regimens were effective in maintaining BW (maximum percent of change, 2.5) and N-balance. Blood products accounted for an additional N-intake of 13% in both groups. The TPN group had a higher dietary N-intake versus PPN/EN, a positive K balance but negative Ca, Mg, Cu, and Zn balances. More mineral supplementation was given in the PPN/EN group where positive K, Mg, and Zn balances were seen. Visceral proteins and IgG, IgA, and IgM levels were decreased on days 7,14, and 21. Creatinine clearance increased significantly in both groups. Compared with TPN, the PPN/EN group showed a twofold number of patients with a positive blood culture, although this observation did not reach statistical significance and patients had fewer days of diarrhea (31.1 % versus 54.3%, P < 0.01). Hyperalimentation with PPN/ EN is an acceptable alternative to TPN in the nutritional support of ABMT recipients.

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Dissociation of body weight and lean body mass during cancer chemotherapy

Cited by 9 publications

References 16 publications

Nutritional considerations in children undergoing bone marrow transplantation

Nutritional considerations in children undergoing bone marrow transplantation

Perspective: Creating the Evidence Base for Nutritional Support in Childhood Cancer in Low- and Middle-Income Countries: Priorities for Body Composition Research

Hyperalimentation in autologous bone marrow transplantation for solid tumors. Comparison of total parenteralVersus partial parenteral plus enteral nutrition

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