Dissolution of Various Calcium Fluoride Preparations in Inorganic Solutions and in Stimulated Human Saliva

Larsen, Mona; Ravnholt, G.

doi:10.1159/000262019

Cited by 22 publications

(20 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…From a chemical point of view, the drinks are poorly defined and unsuited for such studies. Further, we have not used high quality commercial analytical grade calcium fluoride because this salt behaves differently from the low-quality salts that are formed in the oral cavity as a result of topical treatments [Larsen and Ravnholt, 1994]. Generally, after the equilibration with calcium fluoride the drinks were slightly undersaturated with respect to the salt (table 3).…”

Section: Discussionmentioning

confidence: 99%

Prevention by Means of Fluoride of Enamel Erosion as Caused by Soft Drinks and Orange Juice

Larsen¹

2001

Caries Res

Self Cite

View full text Add to dashboard Cite

Fluoride has been suggested to prevent erosion of the teeth, either after a topical treatment of the teeth or by addition of fluoride to the acidic drink. The main aim of the present study was to describe the dissolution of calcium fluoride in some soft drinks and orange juice and compare it with the amounts of calcium fluoride left on the enamel surfaces after a topical treatment. A further aim was to describe the dissolution of enamel in soft drinks and juice saturated for 3 days with solid calcium fluoride. Solid calcium fluoride was suspended in each of 10 soft drinks and orange juices and gently agitated for 72 h, after which the drinks were analyzed for calcium, phosphate and fluoride and pH was determined. To examine the erosion–preventive effect of the calcium fluoride–rich drink, intact teeth were exposed to the drinks with or without calcium fluoride. It was found that from 6 to 45 mg of calcium fluoride was dissolved per liter of drink. The more acidic the drink, the more calcium fluoride was dissolved, presumably due to HF formation. The teeth exposed to the soft drinks all showed erosion–like lesions. Very little effect of the 4–6 ppm ionic fluoride dissolved in the soft drinks was observed. In orange juice, however, the dissolved calcium fluoride established a saturation with respect to fluorapatite and consequently, the erosion–like lesion was replaced by a caries–like lesion. In conclusion, the acidic soft drinks are capable of dissolving considerable amounts of calcium fluoride and the erosion–preventive effect of even high fluoride concentrations is limited.

show abstract

Section: Discussionmentioning

confidence: 99%

Prevention by Means of Fluoride of Enamel Erosion as Caused by Soft Drinks and Orange Juice

Larsen¹

2001

Caries Res

Self Cite

View full text Add to dashboard Cite

show abstract

“…The absence of plaque cancelled a significant source of ions to heal the erosive insult, and this may be a reasonable explanation as to why clarified saliva was associated with a more severe impact on hardness readings. Since centrifugation eliminated solids in suspension, clarified saliva lacked those components of plaque, and fragments of plaque itself, that acted as reservoirs of minerals and fluorides that protected from erosion and/or repaired in situ erosion damage [Jenkins and Ferguson, 1966;Larsen and Ravnholt, 1994;Sorvari et al, 1994]. Featherstone et al [1993] looked at the actual fractions of saliva, endeavouring to accurately establish the protective role of each combination, but found that no specific protein or group of proteins on their own could account for the results observed in whole and dialysed saliva assays.…”

Section: Discussionmentioning

confidence: 99%

In vitro Quantitative Microhardness Assessment of Enamel with Early Salivary Pellicles after Exposure to an Eroding Cola Drink

et al. 1999

View full text Add to dashboard Cite

To assess the erosive effect of a cola drink on enamel incorporating early salivary pellicles, 72 groups of human enamel slabs were immersed in fresh cola, with groups differing in that slabs were (1) incubated in whole or in clarified saliva, (2) under three regimes of frequency intake (1, 5 and 10 times/day); (3) immersed with or without agitation, and (4) the pellicle was incubated for 20 min, 6 or 24 h. Quantitative assessments were done over an 8–day interval using surface microhardness testing. Results for primary enamel showed a sharp decrease from baseline (344.2±32.4 Vickers Units; mean ±SD) to day 1 (268.9±36.8), and reached 155.2±68.6 on day 8. Results for permanent enamel were 350.8±42.2, 315.9±39.2, and 149.8±85.2. Microhardness was affected by agitation, level of intake and type of saliva, but not by the pellicle incubation interval nor the type of enamel. The joint effect of static baths and higher immersion frequency was the most important factor in decreasing hardness.

show abstract

“…For comparison, Coca-Cola ® , Schweppes ® Dry Grape, 7Up ® and an orange juice (Arla ® ) were included as wellknown references. Solid calcium fluoride was produced by slowly mixing equal volumes of 0.25 mol/l CaCl 2 and 0.5 mol/l NaF [Larsen and Ravnholt, 1994]. The salt was aged for 24 h and washed twice in distilled water before drying.…”

Section: Methodsmentioning

confidence: 99%

Fluoride Is Unable to Reduce Dental Erosion from Soft Drinks

Larsen

Richards²

2002

Caries Res

Self Cite

143

View full text Add to dashboard Cite

The main aim of the present study was to compare the erosive capabilities of some fruit-flavoured drinks, fresh or saturated with CaF₂, with their content of acids and with previous results from some carbonated soft drinks. The other aim was to measure and compare the rates of dissolution of CaF₂ in some carbonated and non-carbonated drinks and water. Seven commercially available fruit-flavoured drinks were diluted for drinking. Two human molars, each with two approximately 4 × 4 mm windows, were exposed continuously to 500 ml of each drink with or without prior equilibration with CaF₂ under gentle agitation for 48 h. The depths of the erosions were then measured on microradiographs made from sections. Dissolution rate of CaF₂ was measured by suspending 0.5 g of the salt in 0.5 litre of the drinks for 2, 10 and 60 min followed by solution analysis. The pH of the drinks was 2.83–3.51. The amount of NaOH required to bring pH to 5.5 ranged from 12–42 mmol/l, which is more than the amount necessary for most carbonated soft drinks. Equilibration with CaF₂ gave total fluoride concentrations of 3–8 ppm. The depths of the lesions induced by the drinks without added fluoride were 450–625 µm whilst those developed by the drinks equilibrated with CaF₂ were 350–625 µm. The dissolution of CaF₂ was faster in the carbonated drinks and in distilled water than in the non-carbonated drinks. In conclusion, non-carbonated fruit-flavoured drinks contain considerable amounts of acids which, in vitro, induce erosions in teeth similar to those induced by carbonated soft drinks. Saturation with CaF₂ reduced the in vitro development of erosions by 28% induced by drinks with pH above 3; in drinks with pH below 3, erosions were not affected by pH, despite total fluoride concentrations of up to 20 ppm.

show abstract

Dissolution of Various Calcium Fluoride Preparations in Inorganic Solutions and in Stimulated Human Saliva

Cited by 22 publications

References 20 publications

Prevention by Means of Fluoride of Enamel Erosion as Caused by Soft Drinks and Orange Juice

Prevention by Means of Fluoride of Enamel Erosion as Caused by Soft Drinks and Orange Juice

In vitro Quantitative Microhardness Assessment of Enamel with Early Salivary Pellicles after Exposure to an Eroding Cola Drink

Fluoride Is Unable to Reduce Dental Erosion from Soft Drinks

Contact Info

Product

Resources

About