“…However, the tissue at the region of hypertrophic nonunion is a reservoir of mesenchymal progenitor cells, which can subsequently differentiate into cartilageor bone-forming cells [1], as well as fibrocartilaginous tissue that is capable of osteogenesis once the mechanical instabilities are corrected by establishing a stable osteosynthesis construct [4,5]. Several methods have been described for the correction of facture nonunion, including plate osteosynthesis [6], intramedullary (IM) nailing [7], bone grafting, and external fixation [8,9]. However, these methods have some disadvantages, including complex plating technique, the need for extensive soft-tissue dissection, breakage of plate or screw, and screw loosening [8,10].…”