Distal ureterectomy is a safe surgical option in patients with urothelial carcinoma of the distal ureter

Equivalent survival and improved preservation of renal function after distal ureterectomy compared with nephroureterectomy in patients with urothelial carcinoma of the distal ureter: A propensity score‐matched multicenter study

“…As renal dysfunction caused by radical nephrectomy could be associated with increased risk of overall mortality including cardiovascular events and death, partial nephrectomy is recommended as the standard treatment to preserve renal function for patients with renal cell carcinoma . Similarly, kidney‐sparing surgery could provide clinical benefits for patients with UUT‐UC …”

“…NUx is the gold standard for the treatment of UUT‐UC. However, kidney‐sparing surgery, including segmental or endoscopic resection, could be considered to treat patients with UUT‐UC for improved postoperative renal function preservation . According to the EAU and NCCN guidelines, segmental resection of the distal ureter could be an option even in patients with high‐grade locally‐invasive distal ureteral UC .…”

“…[1][2][3][4][5][6][7][8][9] According to the EAU and NCCN guidelines, segmental resection of the distal ureter could be an option even in patients with high-grade locally-invasive distal ureteral UC. 10,11 However, there have been just three retrospective studies to date that have reported an oncological outcome of DUx in patients with distal ureteral tumors, 7,12,13 and the feasibility of DUx on oncological outcomes remains unknown. Also, little data exist on whether DUx contributes to good preservation of postoperative renal function, which could lead to increased tolerance of adjuvant cisplatin-based chemotherapy.…”

Ureterorenoscopy for Upper Tract Urothelial Carcinoma: How Often Are We Missing Lesions?

“…Retrospective reviews have shown that distal ureterectomy is a safe surgical option in patients with disease limited to the distal ureter. 21 In our study, we identified 11 patients who were found to have a solitary lesion in the distal ureter on URS. Of these 11 patients, 27% had a missed lesion in the renal pelvis found on the final surgical pathology.…”

Kidney-sparing Management Versus Nephroureterectomy for Upper Tract Urothelial Carcinoma: a Systematic Review and Meta-analysis

“…Hence, we selected the one with more areas and patients. After rounds of screening, twenty-three studies including 1587 KS and 3996 NU patients were enrolled meta-analysis at last (Hall et al, 1998;Shiraishi et al, 2003;Chen et al, 2005;Roupret et al, 2006;Giannarini et al, 2007;Lehmann et al, 2007;Lucas et al, 2008;Dragicevic et al, 2009;Gadzinski et al, 2010;Jeldres et al, 2010;Raymundo et al, 2011;Bin et al, 2012;Bing-bing et al, 2012;Colin et al, 2012;Grasso et al, 2012;Bagrodia et al, 2013;Cutress et al, 2013;Fajkovic et al, 2013;Klatte et al, 2013;Dalpiaz et al, 2014;Fukushima et al, 2014;Hoffman et al, 2014;Hung et al, 2014). All included studies were retrospective comparative study; no randomized controlled trials were identified.…”