Distortion of finite amplitude ultrasound in lossy media

Haran, Michael E.; Cook, Bill D.

doi:10.1121/1.389043

Cited by 77 publications

(24 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, transmitting a wave at 3-MHz frequency, the shock formation distance is less than 4 cm for an acoustic pressure of 1 MPa and is less than 3 cm if the acoustic pressure is higher than 1.3 MPa. These curves agree with previous statements (Haran and Cook 1983;Szabo et al 1999) and demonstrate that significant nonlinearities can occur in urine at diagnostic frequencies and pressures. In addition to being nonlinear, all the media have acoustical losses due to absorption.…”

Section: Approach and Theorysupporting

confidence: 90%

“…The distortion is due to slight nonlinearities in sound propagation and manifests itself in the frequency domain with the appearance of additional harmonic signals at integer multiples of the original frequency. Acoustic propagation in fluids gives rise to extreme nonlinear effects at diagnostic frequencies (Haran and Cook 1983). Within soft tissues, nonlinear processes also take place, but are attenuated and modified as a result of different acoustic characteristics, mainly high acoustic absorption.…”

Section: Approach and Theorymentioning

confidence: 99%

See 1 more Smart Citation

Noninvasive bladder volume measurements based on nonlinear wave distortion

Bouakaz

Merks

Lancée

et al. 2004

Ultrasound in Medicine & Biology

View full text Add to dashboard Cite

Section: Approach and Theorysupporting

confidence: 90%

Section: Approach and Theorymentioning

confidence: 99%

Noninvasive bladder volume measurements based on nonlinear wave distortion

Bouakaz

Merks

Lancée

et al. 2004

Ultrasound in Medicine & Biology

View full text Add to dashboard Cite

“…These effects have been shown previously for tissue like media in the absence of dispersion (Haran et al, 1983) and including power law dispersion Wallace et al, 2001) for selected media. A closer view of these phenomena can be studied by showing the harmonic amplitude at a given distance, that for reference we choose σ = 1.…”

Section: Nonlinear Efficiencymentioning

confidence: 84%

Optimization of a label‐free biosensor vertically characterized based on a periodic lattice of high aspect ratio SU‐8 nano‐pillars with a simplified 2D theoretical model

Casquel

Holgado

Sanza

et al. 2011

Phys. Status Solidi (c)

View full text Add to dashboard Cite

We have recently demonstrated a biosensor based on a lattice of SU8 pillars on a 1 μm SiO2/Si wafer by measuring vertically reflectivity as a function of wavelength. The biodetection has been proven with the combination of Bovine Serum Albumin (BSA) protein and its antibody (antiBSA). A BSA layer is attached to the pillars; the biorecognition of antiBSA involves a shift in the reflectivity curve, related with the concentration of antiBSA. A detection limit in the order of 2 ng/ml is achieved for a rhombic lattice of pillars with a lattice parameter (a) of 800 nm, a height (h) of 420 nm and a diameter(d) of 200 nm. These results correlate with calculations using 3D‐finite difference time domain method. A 2D simplified model is proposed, consisting of a multilayer model where the pillars are turned into a 420 nm layer with an effective refractive index obtained by using Beam Propagation Method (BPM) algorithm. Results provided by this model are in good correlation with experimental data, reaching a reduction in time from one day to 15 minutes, giving a fast but accurate tool to optimize the design and maximizing sensitivity, and allows analyzing the influence of different variables (diameter, height and lattice parameter). Sensitivity is obtained for a variety of configurations, reaching a limit of detection under 1 ng/ml. Optimum design is not only chosen because of its sensitivity but also its feasibility, both from fabrication (limited by aspect ratio and proximity of the pillars) and fluidic point of view. (© 2011 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

show abstract

“…The authors could find no information for the clinical scenario they consider, of a spherically spreading blast wave of more than 1 GPa peak overpressure, the Gol'dberg numbers for tissue having been characterized for plane wave propagation of pressure fields with amplitudes typical of those generated directly by clinical diagnostic apparatus (Haran & Cook 1983;Duck 2010). In general, B/A varies only by a factor of around 2 between tissue types for a beam of given amplitude, being similar to water for most liquid tissues like urine, and ranging up to double that of water for fat.…”

Section: The Effect Of Tissuementioning

confidence: 98%

The collapse of single bubbles and approximation of the far-field acoustic emissions for cavitation induced by shock wave lithotripsy

et al. 2011

View full text Add to dashboard Cite

Recent clinical trials have shown the efficacy of a passive acoustic device used during shock wave lithotripsy (SWL) treatment. The device uses the far-field acoustic emissions resulting from the interaction of the therapeutic shock waves with the tissue and kidney stone to diagnose the effectiveness of each shock in contributing to stone fragmentation. This paper details simulations that supported the development of that device by extending computational fluid dynamics (CFD) simulations of the flow and near-field pressures associated with shock-induced bubble collapse to allow estimation of those far-field acoustic emissions. This is a required stage in the development of the device, because current computational resources are not sufficient to simulate the far-field emissions to ranges of O(10 cm) using CFD. Similarly, they are insufficient to cover the duration of the entire cavitation event, and here simulate only the first part of the interaction of the bubble with the lithotripter shock wave in order to demonstrate the methods by which the far-field acoustic emissions resulting from the interaction can be estimated. A free-Lagrange method (FLM) is used to simulate the collapse of initially stable air bubbles in water as a result of their interaction with a planar lithotripter shock. To estimate the far-field acoustic emissions from the interaction, this paper developed two numerical codes using the Kirchhoff and Ffowcs William-Hawkings (FW-H) formulations. When coupled to the FLM code, they can be used to estimate the far-field acoustic emissions of cavitation events. The limitation of the technique is that it assumes that no significant nonlinear acoustic propagation occurs outside the control surface. Methods are outlined for ameliorating this problem if, as here, computational resources cannot compute the flow field to sufficient distance, although for the clinical situation discussed, this limitation is tempered by the effect of tissue absorption, which here is incorporated through the standard derating procedure. This approach allowed identification of the sources of, and explanation of trends seen in, the characteristics of the far-field emissions observed in clinic, to an extent that was sufficient for the development of this clinical device.

show abstract

Distortion of finite amplitude ultrasound in lossy media

Cited by 77 publications

References 0 publications

Noninvasive bladder volume measurements based on nonlinear wave distortion

Noninvasive bladder volume measurements based on nonlinear wave distortion

Optimization of a label‐free biosensor vertically characterized based on a periodic lattice of high aspect ratio SU‐8 nano‐pillars with a simplified 2D theoretical model

The collapse of single bubbles and approximation of the far-field acoustic emissions for cavitation induced by shock wave lithotripsy

Contact Info

Product

Resources

About