Distortion Product Otoacoustic Emission Findings in Behçet’s Disease and Rheumatoid Arthritis

Abstract

Background and Objective: This study aimed to assess cochlear functions in Behçet’s disease and rheumatoid arthritis (RA) using otoacoustic emission testing (OAE), which objectively assesses outer hair cells in the cochlea. Methods: Patients with Behçet’s disease (n = 16) and RA (n = 11) as well as 20 controls were tested using pure tone audiometry and transiently evoked (TEOAEs) and distortion product OAEs (DPOAEs). Results: Pure tone results in the Behçet’s group were not significantly different from controls (p > 0.05). Pure tone results in the RA group were significantly different than in controls at 250, 500 and 6,000 Hz (p < 0.05). TEOAEs could be obtained in all participants. DPOAE amplitudes in the RA group and controls were similar (p > 0.05). DPOAE amplitudes were significantly higher in the Behçet’s group than in controls at 1 and 2 kHz (p < 0.05). Conclusion: A subtle deterioration in hearing can be seen at low and high frequencies in RA, which is not related to outer hair cell dysfunction as detected by DPOAE testing. In the patients with Behçet’s disease who have hearing thresholds within the normal limits, outer hair cell functions seem spared with an increased activity in the apical regions of the cochlea.

Investigation of high‐frequency hearing loss and outer hair cell function of the cochlea in patients with psoriasis: a case–control study

“…The inner ear can be the target of autoimmune attack, and sensorineural hearing loss (SNHL) can occur as a complication in various non‐organ‐specific autoimmune diseases; however, the inner ear can also represent the primary focus of an autoimmune inner ear disease. Since the first description of autoimmune sensorineural hearing loss by McCabe in 1979, many studies have been published about hearing in autoimmune diseases such as rheumatoid arthritis, ankylosing spondylitis, Behçet disease, Sjögren syndrome, polyarteritis nodosa and systemic lupus erytematosus . However studies on high‐frequency hearing loss (HFHL) in psoriasis have been very limited.…”

Hearing Loss in Rheumatoid Arhritis

“…Distortion product of otoacoustic emissions in RA patients were similar to control [9,11]. Acoustic reflexes were with normal thresholds, but with occasional prolonged latency.…”

Audiological Findings in Autoimmune Hepatitis: Hearing Loss at High Frequencies

“…It may be due to vasculitis, ossicular involvement, neuritis or ototoxicity of the drugs used for the treatment of rheumatologic diseases (18). Thus, hearing loss may be seen in conductive, sensorineural or in mixed pattern in secondary AIED (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(19)(20). Özcan et al suggested middle ear involvement for the reason of hearing loss in RA (18).…”

“…Bununla birlikte, otoakustik emisyon (OAE) gibi diğer testleri de içeren ve daha büyük örneklem büyüklüğüne sahip başka çalışmalara da ihtiyaç vardır. (5)(6)(7)(8)(9)(10)(11)(12)(13)(14). The inner ear pathologies caused by these disorders are commonly mild and slowly progressive whereas primary AIED is characterized by sudden onset, commonly bilateral, fluctuant and progressive sensorineural hearing loss (SNHL) with accompanying vertigo in some occasions.…”