Distraction osteogenesis of the mandible

Histology of the porcine mandibular distraction wound

“…This idea has led to the construction of epi-periosteal distraction devices 25 and minimally invasive techniques 67 . In distraction of rat 57 and rabbit 42 long bones and sheep 34,54 mandibles, new bone formation was predominantly seen in the sub-/periosteal region. However, there are also reports documenting simultaneous endosteal and periosteal bone formation in these species 3,9 .…”

Uniaxial Mechanical Strain: An In Vitro Correlate to Distraction Osteogenesis

“…Since in vivo histological analysis demonstrates that cells within the distraction gap align parallel to the vector of distraction, we analyzed the cellular response to uniaxial in vitro strain [26]. Under the microscope, unstrained human osteoblasts have a stellate appearance and haphazard arrangement in vitro (Fig.…”

Intraoral distraction osteogenesis for the correction of facial deformities following temporomandibular joint ankylosis: a modified technique

“…KARAHARJU-SUVANTO et al 13 have reported from their study on sheep that the cutting of the intramedullary blood vessels or overlying periosteum does not affect bone healing. In the present study, the inferior alveolar bundle and the overlying periosteum were kept intact at all times, so as to preserve the limited mandibular bone volume and to maintain the integrity of the inferior alveolar nerve.…”