As part of the implementation of the Federal Scientific and Technical Program for the Development of Synchrotron and Neutron Research and Research Infrastructure for 2019–2027, a scientific and educational medical nuclear medicine center (SEMC NM). The task of constructing the SEMC NM also includes the construction of a proton beam therapy center, which should become the basis for long-term development of equipment and technologies for new generations of proton beam therapy, their implementation in practical healthcare by replicating in the constituent entities of the Russian Federation and friendly countries, as well as training personnel (medical physicists and clinicians). The article presents the results of preliminary design of the accelerator equipment for the created proton beam therapy complex, which is implemented on the basis of the proton synchrotron.