Distribution of ABO blood group among fertile and infertile males in central India: a pilot study

Abstract

or stillbirth. [3] Many studies have reported that the ABO blood group is not related to infertility. [4,5] However, Khan et al. [6] reported that the blood group O is related to male infertility. [6] This study was undertaken to investigate any relationship between ABO blood group and male infertility. Materials and Methods Study Design A total number of 88 infertile men were enrolled during July 2009 to January 2011 from different infertility clinics and centers of Bhopal and Rewa district of Madhya Pradesh, India. This study was approved by the ethical committee of the institute, and written consent from all the subjects was obtained. In this, the population was divided into two groups: Group A: 88 infertile men with mean age of 38.63 (±7.13) years were enrolled in this group, which revealed at least 2 years of infertility period. Hormone profile and semen analysis were also done. Background: Blood is an important component of the human body that is responsible for complete human identity. The ABO and Rh groups are very useful for blood transfusion, organ transplantation, biomedical research, and anthropological study. The blood group incompatibility has been associated with some diseases. Objective: To examine the relationship between blood group and infertility in men and to know the frequency of different blood groups among infertile men who were referred from different infertility clinics and centers. Materials and Methods: A total number of 88 infertile men along with 88 fertile men as controls were evaluated using the antigen-antibody agglutination test.

ABO Blood Groups Compatibility and Incompatibility among Basrah Families

“…Several studies have been carried out to evaluate the association of ABO incompatibility in couples with infertility (Behrman,1960 ;Hoff and Bixler, 1986;Dibby;2015).Other studies showed that there is no association between ABO blood groups with male infertility (Prasad et al, (2015) . Hiraizumi et al, (1970), Takano and Miller,(1972) and Ghasemi et al, (2011) showed ABO incompatibility also caused recurrent abortions and hemolytic disease.…”

ABO phenotype-protected reproduction based on human specific α1,2 L-fucosylation as explained by the Bombay type formation

“…The initial reports on lower counts of ovulation-competent eggs in blood group O females (Nejat et al, 2011) have not been confirmed (Spitzer et al, 2014), and the pronounced ovarian hyperstimulation in females with blood group A (Binder et al, 2008) could not be documented in subsequent studies (Pereira et al, 2015). Similarly, the prevalence of male infertility in blood group O males (Khan et al, 2010) was not confirmed in a more recent study (Prasad et al, 2015). These conflicting results may reflect the confounding effect of hidden ethnic diversity in the analysis of genetic statistics from any given contemporary population, in addition to issues with non-comparable experimental designs and techniques.…”