Distribution of ghrelin-like immunoreactive cells in amphioxus, Branchiostoma belcheri – A study of immunohistochemistry

Weng, Youzhu; Hu, Song; Fang, Yue

doi:10.1016/j.pnsc.2007.08.006

Cited by 4 publications

(4 citation statements)

References 22 publications

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“…In invertebrates, very little is known about the presence and functional role of ghrelin and GHSR (Weng et al . ; Mataruga et al . , ).…”

Section: Discussionmentioning

confidence: 99%

“…The existing evidence is a result of applying mammalian tools such as a polyclonal antibody against synthetic mammalian ghrelin (Weng et al . ) or rat ghrelin (Mataruga et al . , ).…”

Section: Discussionmentioning

confidence: 99%

“…Weng et al . described ghrelin‐like immunoreactive cells in various tissues of amphioxus and suggested that ghrelin exerts different physiological functions. Mataruga et al .…”

Section: Discussionmentioning

confidence: 99%

“…). Additionally, the putative presence of ghrelin has been studied in invertebrates such as the cephalochordate amphioxus Branchiostoma belcheri (Weng, Song & Fang ) and the insect Lymantria dispar (Mataruga, Vlahović, Janać, Ilijin, Tomanić, Matić & Mrdaković ) using immunohistochemistry employing antibodies against mammalian ghrelins.…”

Section: Introductionmentioning

confidence: 99%

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Significant improvement of shrimp growth performance by growth hormone-releasing peptide-6 immersion treatments

et al. 2017

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Growth hormone-releasing peptide-6 (GHRP-6) is one of the earliest developed synthetic peptidyl growth hormone secretagogue receptor agonists. These compounds mimic the effect of the endogenous ligand ghrelin. In vertebrates, ghrelin is a potent circulating orexigenic hormone with functional roles in controlling food intake, energy expenditure, adiposity, growth hormone secretion and immunity. Ghrelin has been studied mainly in vertebrates; thus, little is known about its role in invertebrates, including crustaceans. We first evaluated the effect of GHRP-6 injection over feed intake in shrimp and its effects on shrimp growth when the peptide was administrated by successive immersion baths. GHRP-6 increased feed intake, body weight and size, the number of rostral spines and gill branches, protein concentration and haemocyte number in treated shrimps. We also evaluated the peptide uptake and clearance in a pharmacokinetics, using [H 3 ]GHRP-6 administered to postlarvae. Given a limited exposure and efficient clearance of the peptide-associated radioactivity from larvae, our findings suggested that GHRP-6-treated Litopenaeus vannamei can be consumed safely by humans after aquaculture applications. These results propose that GHRP-6 could be an additional tool to study growth physiology in crustaceans and also a promising candidate for development into a new biotechnology product for improving shrimp growth and quality. Aquaculture Research, 2017, 48, 4632-4645 GHRP-6 as growth enhancer in shrimps R Mart ınez et al.

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“…In invertebrates, very little is known about the presence and functional role of ghrelin and GHSR (Weng et al . ; Mataruga et al . , ).…”

Section: Discussionmentioning

confidence: 99%

“…The existing evidence is a result of applying mammalian tools such as a polyclonal antibody against synthetic mammalian ghrelin (Weng et al . ) or rat ghrelin (Mataruga et al . , ).…”

Section: Discussionmentioning

confidence: 99%

“…Weng et al . described ghrelin‐like immunoreactive cells in various tissues of amphioxus and suggested that ghrelin exerts different physiological functions. Mataruga et al .…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations