Distribution of lead in the brain tissues from DNTC patients using synchrotron radiation microbeams

Characterization and Some Physicochemical Aspects of Pathological Microcalcifications

“…Liu et al measured the element distribution in brain sections of rats by SR-XRF . Yoshida et al studied the role of Fe in Parkinson’s disease. − …”

Clinical and biological materials, foods and beverages

“…As for LA-ICP-MS and SIMS, XRF can be applied to elemental mapping in tissues. Distribution of trace elements in brain, 123,124 hair, 114,125 teeth, 126 nails 127 and protein bands separated by electrophoresis 70 were reported. As a matter of interest, one study indicated that Pb in brain was associated with foci where calcification had taken place.…”

“…As a matter of interest, one study indicated that Pb in brain was associated with foci where calcification had taken place. 124…”

Atomic spectrometry update—X-ray fluorescence spectrometry

“…While elements like Br, Ca, Cu, Fe, S and Zn could be clearly assigned to brain vessels, Pb was inhomogeneously distributed, and no systematic increase could be observed in any brain compartments. Ide-Ektessabi et al 89 studied Pb in brain tissues from two groups of patients, one group suffering from diffuse neurofibrillary tangles with calcification (DNTC), a form of dementia, and the other from Alzheimer's disease. Measurements were made with an excitation beam size of 4 Â 6 mm 2 , monochromatized at 14.3 keV.…”