Distribution of ocular biometric parameters and optimal model of anterior chamber depth regression in 28,709 adult cataract patients in China using swept‐source optical biometry

Abstract

Background The purpose of this study was to evaluate the ocular biometric parameters in adult cataract patients from China and create an anterior chamber depth (ACD) regression model. Methods The ocular biometric records of 28,709 right eyes of cataract surgery candidates who were treated at Aier Eye Hospitals in nine cities from 2018 to 2019 were retrospectively analyzed. All measurements were taken with IOLMaster 700. We included patients who were at least 40 years old and were diagnosed with cataract. Results The mean age of the patients was 68.6 ± 11.0 years. The mean values recorded were as follows: axial length (AL), 24.17 ± 2.47 mm; mean keratometry (Km) value, 44.26 ± 1.70 D; corneal astigmatism (CA), 1.06 ± 0.96 D; ACD, 3.02 ± 0.45 mm; lens thickness (LT), 4.52 ± 0.45 mm; central corneal thickness (CCT), 0.534 ± 0.04 mm; and white to white (WTW) corneal diameter, 11.64 ± 0.46 mm. ACD correlated positively with AL (Spearman coefficient, 0.544) and WTW (0.300), but negatively with LT (-0.660) and age (-0.285) (all P < 0.01). In the multivariate regression analysis of ACD, which included LT, AL, WTW, sex, Km, CCT, and age, there was a reasonable prediction with adjusted R2 = 0.641. Conclusions Cataract patients with longer AL and wider WTW have deeper ACD. With increasing age and lens thickening ACD becomes shallower. Based on the standardized coefficients of ACD multivariate regression analysis from the study, LT is the main factor that affects ACD, and is followed by AL.

SS-OCT–based ocular biometry in an adult Korean population with cataract

“…Previously, various studies reported about the relationship between age and ocular biometric parameters, and of those, IOLMaster 700 was used in 5 studies from 2 countries (China and Israel). 1,5,[19][20][21][22][23][24][25][26][27][28][29][30][31] Age was shown to have a positive correlation with LT and AK and a negative correlation with AL, ACD, and WTW in Chinese patients, which were consistent with our data. 1 Meng et al reported that older age, lower AK, shorter WTW, and shallower ACD showed higher angle a or angle k in Chinese patients.…”

“…With the introduction of premium IOLs, such as toric and multifocal IOLs, it has become increasingly important to fully understand the factors related to ocular biometric parameters. 1,2 The ocular biometric parameters are interrelated and tend to change with age. [3][4][5] The parameters are different according to the ethnicity and region.…”

“…Large population-based studies on ocular parameters measured using IOLMaster 700 have been reported in China and Israel. 1,5 However, there is no study evaluating the ocular biometric values using IOLMaster 700 in a Korean population. Herein, we evaluated age-dependent changes and the correlation among ocular biometric parameters measured by the IOLMaster 700 in Korean patients undergoing cataract surgery.…”

Clinical presentation of acute primary angle closure during the COVID-19 epidemic lockdown

“…Our results showed that the AL was < 22.5 mm and the depth of the ACD was < 2.5 mm in both groups. Previous studies by Lei et al (19) showed that nearly 12% of Chinese elderly participants had an ACD < 2.5 mm. Therefore, the prevention and treatment of glaucoma should be strengthened for the elderly population with similar ocular biometry, such as short AL.…”

Anterior chamber parameters in cataract surgery candidates from middle China

“…[ 5 ] On the other hand, LT is the main factor that affects anterior chamber depth (ACD). [ 6 ] Therefore, we should pay more attention to the anterior chamber parameters of adult cataract patients and be alert to the PACG. In routine clinical use, gonioscopy is the most common method to evaluate the anterior chamber angle, which is subjective and highly dependent on the examiner’s judgement and experience.…”