Distribution of procoagulant activity in the subcellular fractions of human granulocytes

Szpilman, H; Prokopowicz, J; Niewiarowski, S

doi:10.1007/bf01903908

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Chronic Granulocytic Leukemia Cells and Hemorrhagic Complica1

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1972

2008

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Cited by 3 publications

(2 citation statements)

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“…The procoagulant activity of these granulocytes is, however, weaker than that of platelets. This activity is probably located in the lysosomal granules [149]. The characteristics of these substances are similar to those of tissue thromboplastin (Fig.…”

Section: Chronic Granulocytic Leukemia Cells and Hemorrhagic Complicamentioning

confidence: 55%

Mechanisms of Hemorrhage in Leukemias

Lisiewicz¹

2008

Semin Thromb Hemost

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Section: Chronic Granulocytic Leukemia Cells and Hemorrhagic Complicamentioning

confidence: 55%

Mechanisms of Hemorrhage in Leukemias

Lisiewicz¹

2008

Semin Thromb Hemost

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“…In previous experiments using leukocytes preparations (22) we have shown adsorption of Hageman factor activity by kaolin and its elution at alkaline pH. That may indicate that this factor is present in the granulocytes.…”

Section: Discussionmentioning

confidence: 65%

The Purification of Activated Hageman Factor from Human Granulocytes

Prokopowicz¹,

Wołosowicz²,

Szmitkowski³

1972

Thromb Haemost

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SummaryActivated Hageman factor has been isolated from human granulocytes, utilizing aluminium hydroxide gel, diatomaceous earth, CM-cellulose. The preparation was applied on the column prepared from DEAE-Sephadex A-50. Two peaks with Hageman activity were obtained. The product was purified 4162-18750-fold as measured by the method of Schoenmakers et al.The preparation was devoid of factor I, II, III, V, VIII, IX and plasminogen. Some relationship between granulocyte and plasma Hageman factor are briefly discussed.

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Lysosomal Hydrolases and Inflammatory Materials

Goldstein

1974

Mediators of Inflammation

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Distribution of procoagulant activity in the subcellular fractions of human granulocytes

Cited by 3 publications

References 0 publications

Mechanisms of Hemorrhage in Leukemias

Mechanisms of Hemorrhage in Leukemias

The Purification of Activated Hageman Factor from Human Granulocytes

Lysosomal Hydrolases and Inflammatory Materials

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