Distribution of Receptors to Lectins in the Schneider Membrane Under Various Etiopathogenetic Forms of the Yatrogenic Maxillar Sinusite

Abstract

The development of modern technologies contributes to the increase in the number of iatrogenic diseases. The article presents the distribution of glucoconjugates in the structures of the Schneider membrane under various etiopathogenetic forms of the iatrogenic maxillary sinusitis of dentition.Key words: lectinhistochemistry of the Schneider membrane, iatrogenic maxillary sinusitis, iatrogenic concomitant diseases.Relevance. Modern stomatology can't be imagined without the use of high technology. There is a constant modernization of this branch of medicine. The development of medical technologies, as one of the reasons for the increase in the number and frequency of iatrogenic diseases, is noted by many modern authors [1, 3, 7].With the introduction of new methods of treatment, the habitual picture of pathological conditions associated with medical intervention changes. One of the important points in the strategy of the disease investigation is the systematization of its individual forms. Due to the lack of a separate classification, all dental iatrogenic diseases are considered within the framework of generally accepted medical diagnostic protocols. This leads to standardization of treatment of diseases that do not have a common origin and pathogenesis.A new etiopathogenetic classification of iatrogenic maxillary sinusitis of stomatogen origin included the forms most commonly found in the clinic [4]. In earlier publications, we cited the results of clinical, radiological, ultrasound and morphological studies of the Schneider membrane in these diseases. To study the characteristics of the inflammatory process at the level of carbohydrate compounds (nanolevel), a relatively new lectinhistochemical method was chosen [6]. In recent years, there has been a tendency towards a wide use of lectins as indicators of the depth of changes in tissues in various pathological processes. This, as well as the use of new classes of carbohydrate-containing drugs in medicine, determines the relevance of this method of research [6,8]. Despite the considerable interest of researchers in the study of the carbohydrate code for diseases, there is no information in the scientific literatureon the nature of the distribution of carbohydrate residues in the maxillary sinusitis that developed against the background of thestomatologic manipulation.the aim of the study was to study in a comparative aspect the expression of the PSA, WgA, LABA, SBA and Con A lectin receptors in the structures of the maxillary sinus mucosa at various etiopathogenetic forms of iatrogenic maxillary sinusitis of stomatologic origin.Material and methods. Sampling of biomaterial -a portion of the mucous membrane of the maxillary sinus was performed by in 115 (100 %) patients, which were distributed according to etiopathogenetic groups of iatrogenic maxillary sinusitis of stomatologic origin [4]. Into the group of infectious-allergic form of iatrogenic maxillary sinusitis (IAFIMS) there were 22 (19.1%) patients who had established a periapical infection of previously t...