Distribution of various subtypes of non-Hodgkin's lymphoma in India: A study of 2773 lymphomas using R.E.A.L. and WHO Classifications

Naresh, Kikkeri N.; Srinivas, Vijaya; Soman, C. S.

doi:10.1093/annonc/11.suppl_1.s63

Cited by 122 publications

(116 citation statements)

References 14 publications

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“…The low proportion of HL in our study (4.1% of total lymphoid neoplasms) was also in good agreement with previous results from Asian countries [1,2,6,9,[13][14][15][16][17][18][19][20][21]23,[25][26][27][28][29][30][31][32][33][34][35][36]38,45,46]. Although the proportion of overall HL was low, subtype distribution showed similar pattern to previous studies from various regions, with nodular sclerosis and mixed cellularity being the common subtypes (Supplementary Table III).…”

Section: Discussionsupporting

confidence: 93%

“…As for MCL, no remarkable difference was noted between countries. Among the mature T/NK-cell neoplasms, peripheral T-cell lymphoma and extranodal NK/T-cell lymphoma of nasal type exhibited similar proportions, as has been shown in other studies from East Asian countries, and these subtypes were much more common than those of Western countries (Supplementary Table III) [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32]37,40]. We found that the proportion of patients with ALL/ABL (16.4% of total lymphoid neoplasms) was in agreement with the nationwide incidence ratio based on Korea National Cancer Incidence Database of the period 1999-2005 (Supplementary Table IV) [11], but was much higher than that in previous reports from Korea (3.4-5.5%) [19,21,23].…”

Section: Discussionsupporting

confidence: 69%

“…Our current knowledge of NHL subtype distribution in Asia is based primarily on studies of lymphomas, the solid phase, in adult populations [20][21][22][23][24][25][26][27][28][29][30][31][33][34][35][36][37][38]40,41]. Although these data effectively characterize the subtype spectrum of lymphomas [18][19][20][21][22][23][24][26][27][28][29][30][31][32][33][34][35], most studies have excluded the majority of plasma cell neoplasms and leukemias (circulating phase).…”

Section: Introductionmentioning

confidence: 99%

“…Although these data effectively characterize the subtype spectrum of lymphomas [18][19][20][21][22][23][24][26][27][28][29][30][31][32][33][34][35], most studies have excluded the majority of plasma cell neoplasms and leukemias (circulating phase). Therefore, these results may not be comparable with population-based incidence data for the entire spectrum of WHO classifications [10,42,43].…”

Section: Introductionmentioning

confidence: 99%

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Distribution of lymphoid neoplasms in the Republic of Korea: Analysis of 5318 cases according to the World Health Organization classification

et al. 2010

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Compared with the West, the overall incidence of lymphoid neoplasms is lower, and the subtype distribution is distinct in Asia. To comprehensively investigate the subtype distribution with the age and sex factors, and temporal changes of subtype proportions, we re-assessed all patients with lymphoid neoplasms diagnosed at a large oncology service in the Republic of Korea from 1989 to 2008 using the World Health Organization classifications. Of the total 5,318 patients, 66.9% had mature B-cell neoplasms, 12.5% had mature T/natural killer (NK)-cell neoplasms, 16.4% had precursor lymphoblastic leukemia/lymphoma (ALL/LBL), and 4.1% had Hodgkin's lymphoma. The most common subtypes were diffuse large B-cell lymphoma (30.5%), plasma cell myeloma (14.0%), extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type (MALT lymphoma; 12.4%), B-cell ALL/LBL (11.3%), Hodgkin's lymphoma (4.1%), peripheral T-cell lymphoma unspecified (4.0%), T-cell ALL/LBL (3.9%), and extranodal NK/T-cell lymphoma of nasal type (3.9%). Most subtypes showed male predominance, with an average M/F ratio of 1.3. Most mature lymphoid neoplasms were diseases of adults (mean age, 53.5 yr), whereas ALL/LBLs were of young individuals (mean age, 20.3 yr). When the relative proportion of subtypes were compared between two decades (1989-1998 vs. 1999-2008), especially MALT lymphoma has increased in proportion, whereas T/NK-cell neoplasms and ALL/LBL have slightly decreased. In summary, the lymphoid neoplasms of Koreans shared some epidemiologic features similar to those of other countries, whereas some subtypes showed distinct features. Although the increase in incidence of lymphoid neoplasms is relatively modest in Korea, recent increase of MALT lymphoma and decrease of T/NK-cell neoplasms and ALL/LBL are interesting findings. Am. J. Hematol. 85:760-764, 2010. V V C 2010 Wiley-Liss, Inc. IntroductionLymphoid neoplasms are a diverse group of neoplasms with different clinical presentations, histology, and biology [1,2]. Recent revolutionary advances in immunology, genetics, and molecular biology have resulted in extensive changes in the classifications of these tumors, culminating in the Revised European-American classification (1994) and its successor, the World Health Organization (WHO) classification (2001 and 2008) [1][2][3]. Both Revised European-American and WHO classifications encompass not only Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL) but also plasma cell neoplasm and lymphoid leukemia, acknowledging that lymphoma and lymphoid leukemia represent solid and circulating phases, respectively, of the same disease [1][2][3]. Lymphoid neoplasms are the sixth most common malignancy worldwide [4,5], but there are marked geographic variations, with the highest rates observed in North America and Australia, followed by Europe, and lower rates throughout Asia [4,5].There are ethnic and regional differences in the distribution of subtypes. For example, populations of Asian countries have higher proportions of mature T/natural k...

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 69%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Distribution of lymphoid neoplasms in the Republic of Korea: Analysis of 5318 cases according to the World Health Organization classification

et al. 2010

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“…The incidence is stated to be much lower in the Asian countries and about 12 % in the Indian population [3]. It is an indolent and clinically heterogeneous disease, with median survival expectations of 8-10 years.…”

Section: Introductionmentioning

confidence: 99%

Nodal Follicular Lymphomas: A Clinicopathological Study from a Tertiary Care Centre in South India

Supari

Ananthamurthy

2015

Indian J Hematol Blood Transfus

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The aim of this study was to assess the distribution of nodal follicular lymphomas (FL) among various subtypes of non-Hodgkin lymphoma and to study their clinico-pathological features. Clinical details, histomorphology including grading & patterns and immunoprofile of 44 cases were studied. Majority of the cases were grade 1 (61 %) FL. BCL2 positivity was higher in low grade FLs (97 %). An associated diffuse large B cell lymphoma component was seen in 18 % and was present only in conjunction with grade 3 FL. Majority of our patients (76 %) had a high FLIPI score and belonged to the high risk group. Our study showed that the incidence of FLs is much lower in the Indian population (14.5 %) when compared to western studies and majority were of low grade. Although there was complete initial response to treatment, relapse was common and was much higher in low grade FLs with diffuse areas on histology, Ann Arbor stage III/IV and FLIPI scores of 3-5.

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Natural Killer/T‐cell Lymphomas

Kim

Suzuki

Jaccard

et al. 2021

The Peripheral T‐Cell Lymphomas

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Distribution of various subtypes of non-Hodgkin's lymphoma in India: A study of 2773 lymphomas using R.E.A.L. and WHO Classifications

Cited by 122 publications

References 14 publications

Distribution of lymphoid neoplasms in the Republic of Korea: Analysis of 5318 cases according to the World Health Organization classification

Distribution of lymphoid neoplasms in the Republic of Korea: Analysis of 5318 cases according to the World Health Organization classification

Nodal Follicular Lymphomas: A Clinicopathological Study from a Tertiary Care Centre in South India

Natural Killer/T‐cell Lymphomas

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