Disturbance in glucose metabolism in patients with lichen planus

Zakaria, Asm; Hossain, Md. Kamal; Bhuiyan, Mohammed Saiful Islam; Sultana, Abida; Rahman, Mustafizur; Kulsom, Ommey

doi:10.3329/bsmmuj.v9i4.29993

Cited by 2 publications

(4 citation statements)

References 6 publications

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“…Although the exact aetiology is unknown, OLP often considered as a hypersensitivity reaction. Strong association with emotional stress, antihypertensive drugs, NSAIDs, infectious disease, and Glucose metabolism disturbances reported as associated risk factors for OLP 43 . Different clinical forms of OLP are detected, such as, reticular, erosive, atrophic, bullous, and plaque types.…”

Section: Oral Lichen Planusmentioning

confidence: 95%

“…This is a T-cell mediated autoimmune disease, in which the cytotoxic CD8+ cells lead to the apoptosis of the basal cells of the oral epithelium. The OLP is common in all cultures around the world, and comprises more than 0.5% of all dermatological visits 43 . Although the exact aetiology is unknown, OLP often considered as a hypersensitivity reaction.…”

Section: Oral Lichen Planusmentioning

confidence: 99%

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Oral Potentially Malignant Disorders: A review on Bangladesh perspective

Shaikh,

Iqbal,

Sadat

2023

J. Bangladesh Coll. Phys.

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Oral potentially malignant disorders (OPMDs) are a group of chronic conditions affecting the oral mucosa with a risk of transformation to oral squamous cell carcinoma (OSCC). Oral leukoplakia, oral submucous fibrosis, oral lichen planus, and oral erythroplakia are the most common OPMDs observed in South Asian population. However, oral leukoplakia and oral lichen planus are commonly encountered OPMDs in clinical practice in Bangladesh, possibly, owing to specific lifestyle habits. Although the exact aetiology is unknown, use of smokeless tobacco, smoking, and chewing of betel quid containing areca nut, are considered as common risk factors for OPMDs. Early diagnosis is very important and can be lifesaving, as at a late stage, OPMDs are more likely to progress into severe dysplasia or even into squamous cell carcinoma. In fact, OPMDs have a significantly increased risk of progressing to cancer, mostly in South Asian population, including Bangladesh. This review provides an overview of the OPMDs in Bangladeshi population. J Bangladesh Coll Phys Surg 2023; 41(4): 305-314

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Section: Oral Lichen Planusmentioning

confidence: 95%

Section: Oral Lichen Planusmentioning

confidence: 99%

Oral Potentially Malignant Disorders: A review on Bangladesh perspective

Shaikh,

Iqbal,

Sadat

2023

J. Bangladesh Coll. Phys.

View full text Add to dashboard Cite

show abstract

“…6 It is thought that insulin-like growth factor receptors (IGF-1 Rs) are found in keratinocytes in aetiopathogenesis and that the increase in insulin in the blood affects these receptors. 7 AN is a dermatological clue to hyperinsulinaemia and has been linked with metabolic syndrome. 8 Acrochordons are small, soft, benign cutaneous tumours and these lesions appear in fold areas.…”

mentioning

confidence: 99%

“…found an average of 24.2 kg/m 2 , and Eshkevari et al22 found an average of 27.5 kg/ m 2 . Zakaria et al7 have found that patients with lichen planus have a strong risk of glucose metabolism disturbance, especially diabetes mellitus. Research results on the relationship between DM and LP are in conflict.…”

mentioning

confidence: 99%

Relationship between acanthosis nigricans, acrochordon and metabolic syndrome in patients with lichen planus

et al. 2021

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The prevalence of LP is almost 0.89% of the population, and it commonly affects middle-aged individuals of both genders. The pathogenesis and aetiology of the disease are not completely known. 1 LP is a T cell-mediated auto-inflammatory disease. In pathogenesis, T cell activation acts a significant role. Activated T-cells induce the T helper type 1 (Th1) response. 2 An inflammatory response caused by Th1 cytokines (IL-2, 4, 6, 10) and TNFα also acts a role in the pathogenesis of metabolic syndrome. 3 Dyslipidaemia, which is one of the metabolic syndrome components, has been found to be associated with LP. Chronic inflammation is the main factor in its relationship with dyslipidaemia in patients with LP. 3 The relationship of chronic inflammatory skin diseases with MS has been more clearly demonstrated in recent years. 3 Again, in this context, the number of publications showing the relationship with MS in lichen planus patients has increased. 1,4 Acanthosis nigricans is a clinical finding described by asymptomatic plaques that are grayish-brown or black in color, raised from the skin, lichenified, velvety, and violase, with no sharp borders, located in intertriginous areas such as axilla, neck, and groin. 5 Hyperkeratosis and papillomatosis are prominent in histopathological examination. 5

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Disturbance in glucose metabolism in patients with lichen planus

Cited by 2 publications

References 6 publications

Oral Potentially Malignant Disorders: A review on Bangladesh perspective

Oral Potentially Malignant Disorders: A review on Bangladesh perspective

Relationship between acanthosis nigricans, acrochordon and metabolic syndrome in patients with lichen planus

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