Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters

Xu, Benjamin; Penteado, Rafaella C.; Weinreb, Robert N.

doi:10.1097/ijg.0000000000000832

Cited by 12 publications

(7 citation statements)

References 30 publications

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“…Third, testing was performed at all times of day. While it is possible diurnal variation affects properties of ACA structures, these do not appear to affect ACA configuration 21,22. Finally, one observer graded all of the AS-OCT images.…”

Section: Discussionmentioning

confidence: 99%

Differences in Anterior Chamber Angle Assessments Between Gonioscopy, EyeCam, and Anterior Segment OCT: The Chinese American Eye Study

Pardeshi

Burkemper

et al. 2019

Trans. Vis. Sci. Tech.

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Purpose To quantify interquadrant differences in anterior chamber angle (ACA) configuration assessed on gonioscopy, EyeCam, and anterior segment optical coherence tomography (AS-OCT) in a cohort of Chinese Americans. Methods Subjects aged 50 years or older were recruited from the Chinese American Eye Study (CHES), a population-based epidemiologic study in Los Angeles, CA. Each subject underwent a complete ocular exam, including gonioscopy, EyeCam, and AS-OCT, under dark ambient lighting. Gonioscopy and AS-OCT imaging and EyeCam image grading were performed by trained ophthalmologists. Results Seven hundred nine eyes from 709 subjects were analyzed. Less anatomic variation among the quadrants was detected on gonioscopy and EyeCam compared with AS-OCT ( P < 0.05). The mean gonioscopy grade, EyeCam grade, and AS-OCT measurement for each quadrant varied by up to 10.3%, 6.4%, and 46.2% of the superior quadrant value, respectively. There were significant interquadrant differences ( P < 0.05) among mean AOD750 measurements when grouping by quadrant and gonioscopy or EyeCam grade. Mean AOD750 measurements were smallest for the superior quadrant by between 14.3% and 38.1% and 17.4% and 37.9% on gonioscopy and EyeCam, respectively, compared with other quadrants. Conclusions Gonioscopy and EyeCam significantly underrepresent anatomic variations of the ACA compared with AS-OCT. Gonioscopy or EyeCam grades from different quadrants do not appear to be comparable or interchangeable, which supports reconsideration of current definitions and methods used to diagnose and manage primary angle closure disease. Translational Relevance AS-OCT imaging raises concerns about current clinical definitions and methods that rely gonioscopy or EyeCam to assess the ACA.

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Section: Discussionmentioning

confidence: 99%

Differences in Anterior Chamber Angle Assessments Between Gonioscopy, EyeCam, and Anterior Segment OCT: The Chinese American Eye Study

Pardeshi

Burkemper

et al. 2019

Trans. Vis. Sci. Tech.

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“…The CASIA2 is designated for cross-sectional imaging of the anterior segment components of the human eye such as the cornea, the bleb segment of the sclera, the anterior chamber, and also for the measurements of their dimensions such as curvature length area and volume by computed analysis. 20,26 The CASIA2 uses a swept-source laser with a wavelength of 1310-nm at a velocity of 50,000 A-scan/second. It has an auto-alignment function and can assess the value quality of the operator during the acquisition.…”

Section: Methodsmentioning

confidence: 99%

“…A few studies have described these parameters in high myopia but the results are conflicting due to limitation in technology and equipment. [16][17][18][19] In this study, we aimed to investigate the corneal parametric features and their correlation with AL in high myopia and the age-sex matched control to address the conflicting conclusions reported by previous studies using the latest anterior segment swept-source optical coherence tomography (SS-OCT) which has a faster scanning speed and advanced imaging, 20 allows comprehensive assessment of corneal parameters.…”

Section: Introductionmentioning

confidence: 99%

Corneal Biometric Features and Their Association With Axial Length in High Myopia

Jin

Liu

Wang

et al. 2022

American Journal of Ophthalmology

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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“…SS-OCT assessment of the anterior chamber angle is an especially useful measurement technique due to its short measurement time and its non-contact nature. Repeated measurements of the angle can be useful to evaluate diurnal changes [38]. Furthermore, can be used to evaluate the iris and angle configuration before and after laser iridotomy.…”

Section: Ss-oct and Anterior Chamber Evaluationmentioning

confidence: 99%

Anterior Segment OCT

Asam

Polzer

Tafreshi

et al. 2019

High Resolution Imaging in Microscopy and Ophthalmology

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Diurnal Variation of Optical Coherence Tomography Measurements of Static and Dynamic Anterior Segment Parameters

Abstract: No significant diurnal variation of static or dynamic anterior segment parameter measurements was detected in the light and dark. Diurnal variation of these parameters does not regularly occur in young, healthy eyes.

Cited by 12 publications

References 30 publications

Differences in Anterior Chamber Angle Assessments Between Gonioscopy, EyeCam, and Anterior Segment OCT: The Chinese American Eye Study

Differences in Anterior Chamber Angle Assessments Between Gonioscopy, EyeCam, and Anterior Segment OCT: The Chinese American Eye Study

Corneal Biometric Features and Their Association With Axial Length in High Myopia

Anterior Segment OCT

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