Diurnal variations of plasma testosterone in men

Barberia, Juan M.; Giner, Juan Manuel Llopis; Cortés-Gallegos, V.

doi:10.1016/0039-128x(73)90110-4

Cited by 37 publications

(16 citation statements)

References 27 publications

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“…The reduced plasma androgens and E2 concentrations found after the restless period could represent an adaptative response to the acute stress and certainly is not due to a methodology artifact, since the hormonal concentrations observed in the phase 1 (control) closely agree with those previously reported from our laboratory [2,4] as well as with those reported by others [lo, 161. The lack of significant changes in C levels could be explained in several ways: a) It is an emergency reaction to maintain corticosteroid synthesis as normal as possible; b) An acute sleep deprivation present only once may not be sufficient to induce any detectable changes and; c) The peripheral cortisol concentrations are not necessarily linked to the sleep phenomenon [ 191.…”

Section: Discussionsupporting

confidence: 89%

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Sleep Deprivation Reduces Circulating Androgens in Healthy Men

Cortés-Gallegos

Alonso

et al. 1983

Archives of Andrology

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The acute effect of sleep deprivation on the pituitary-testis axis was evaluated in 13 healthy men. To study such association, the circulating levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), Androstenedione (A), Testosterone (T), Dihydrotestosterone (DHT) and Estradiol (E2) were measured along with Cortisol (C) before and after sleep deprivation. Morning (8:OO AM) venous blood samples were obtained prior and after a continuous restless period of 24 hr and the values were analyzed by the paired Student's r test. There was a significant and parallel decrease of each androgen and E2 but not of FSH, LH.PRL, or C, associated with the acute sleep deprivation.

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Section: Discussionsupporting

confidence: 89%

“…Many of our physiological functions are known to exhibit a diurnal variation [2,6,9,11,15, 171 and the change from light to darkness signals a repetitive phenomenon, sleep. A great deal of experimental and clinical evidence has emerged showing that the endocrine system is intimately linked with the sleep rhythm [8, 18,191.…”

Section: Introductionmentioning

confidence: 99%

Sleep Deprivation Reduces Circulating Androgens in Healthy Men

Cortés-Gallegos

Alonso

et al. 1983

Archives of Andrology

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“…Differing collection protocols can also contribute to variation, since hormone results can vary significantly within minutes as a result of secretion pulsatility and diurnal variation (Barberia et al, 1973;Faimanand Winter, 1971;Rose et al, 1972;. With the advent of less invasive sampling methods, including salivary and blood-spot collection protocols (Ellison, 1988;Worthman and Stallings, 1994), most investigations are able to incorporate multiple samples to account for pulsatility and diurnal variation.…”

Section: Collection and Assessment Methodsmentioning

confidence: 99%

“…Typically, testosterone exhibits a diurnal pattern of intraindividual variation, with morning titers being significantly higher than evening titers (Barberia et al, 1973;Faiman and Winter, 1971;Rose et al, 1972), although diurnal differences may diminish with age (Bremner et al, 1983). Between-individual variation is considerable, with salivary tes- Fig.…”

Section: Reproductive Endocrinologymentioning

confidence: 99%

Reproductive ecology and life history of the human male

Bribiescas

2001

Am. J. Phys. Anthropol.

211

117

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Until recently, the reproductive ecology of human males has not been extensively investigated, primarily as a result of the need for a theoretical framework based on the reproductive constraints and energetics of mammalian males. More specifically, male reproductive ecology has necessitated an integrative interpretation of clinical and anthropological data based on the premise that the evolution of human male life histories has involved selection for physiological mechanisms aimed at optimizing trade-offs between survivorship and reproductive effort. This paper attempts to address this gap in our understanding by presenting the current state of male reproductive ecology, including physiologic data from clinical and anthropological investigations as well as recent theoretical developments. Recent investigations outlining population variation in reproductive endocrine function are discussed within the context of potential sources of variation, including energetic expediture, caloric intake, and developmental canalization during adolescence. Additional summaries of male senescence and behavior are presented to provide a complete overview of male life history. Implications of recent anthropological data on contemporary health issues such as prostate cancer and the development of a male contraceptive are also discussed. Finally, several theories are presented that may contribute to our understanding of the evolution of male life histories and reproductive ecology, including theoretical suggestions involving the role of competition, mate choosiness, and potential constraints on male insemination ability, as well as a theory suggesting that male reproductive ecology may be best understood by analyzing energetic allocation decisions between differing somatic tissues that may be indicative of the competing needs for optimizing survivorship and reproductive effort. Directions for future research are finally considered.

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“…Several endocrinological responses have been observed to occur at certain critical periods in body time [2,3,10,11,13,181. In some instances repetitive biological phenomena display a well-characterized rhythm, expressing this periodicity in forms of predicting or anticipating particular events [4,14,15, 231.…”

Section: Introductionmentioning

confidence: 99%

Sleep Deprivation and Adaptive Hormonal Responses of Healthy Men

et al. 1989

Archives of Andrology

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To study the effects of sleep deprivation on the pituitary-testis axis physiology, we measured the circulating levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), testosterone (T), androstanedione (A), dihydrotestosterone (DHT), estradiol (E,), and cortisol (C) in eight healthy men as follows: phase I (control), phase II (24-h restless period), phase JII (48-h restless period), and phase N (24-h recovery period). All samples were taken at 8:OO a.m. There was a significant decrease of T, A, DHT, and E, in phase II but no decrease in FHS, LH, PRL, or C. In phase I11 there was no further decrease in any androgen, although E, decreased along with the increase of PRL. In phase N E, and PRL tended to return to baseline values, and the androgens were very similar to the controls. FHS, LH, and C showed no change under the effects of phase III. These data extend the adaptive androgenic response and the association of the role of E, and PRL to restricted or disturbed sleep in men.

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Diurnal variations of plasma testosterone in men

Cited by 37 publications

References 27 publications

Sleep Deprivation Reduces Circulating Androgens in Healthy Men

Sleep Deprivation Reduces Circulating Androgens in Healthy Men

Reproductive ecology and life history of the human male

Sleep Deprivation and Adaptive Hormonal Responses of Healthy Men

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