2007
DOI: 10.1080/07328300701540225
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Divergent Synthesis of All Possible Optically Active Regioisomers ofMyo‐Inositol Mono‐ and Bisphosphates

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Cited by 3 publications
(2 citation statements)
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“…Although this methodology is not meant for a process scale-up application, it proved to be efficient in the preparation of a chiral inositol bisphosphates library. Their preparation starting from the commercially available myo -inositol was achieved in a record number of four steps and a maximum of seven steps, while synthesis using classic chiral resolution or chiral substrate starting material suffers from multiple protection/deprotection steps …”
mentioning
confidence: 99%
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“…Although this methodology is not meant for a process scale-up application, it proved to be efficient in the preparation of a chiral inositol bisphosphates library. Their preparation starting from the commercially available myo -inositol was achieved in a record number of four steps and a maximum of seven steps, while synthesis using classic chiral resolution or chiral substrate starting material suffers from multiple protection/deprotection steps …”
mentioning
confidence: 99%
“…Their preparation starting from the commercially available myo-inositol was achieved in a record number of four steps and a maximum of seven steps, while synthesis using classic chiral resolution or chiral substrate starting material suffers from multiple protection/deprotection steps. 25 This cyclic C 2 -symmetric phosphoramidite comes to expand the toolbox for general chiral inositol phosphates synthesis. The reactivity, similar to the widely used xylylene phosphoramidite, should also give the possibility to rapidly access numerous chiral inositol phosphates as well as their metabolically stable analogues thiophosphates.…”
mentioning
confidence: 99%