Diverse Findings in Calcified Thrombus Between Histopathology and &lt;i&gt;In Vivo&lt;/i&gt; Imaging Including Intravascular Ultrasound, Optical Coherence Tomography, and Angioscopy

Koga, Seiji; Ikeda, Satoshi; Nakata, Tomoo; Kawano, Hiroaki; Abe, Kuniko; Maemura, Koji

doi:10.1536/ihj.15-117

Cited by 7 publications

(5 citation statements)

References 16 publications

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“…The role of calcification in the progression of arterial stiffness has been raised as a critical research question by KDIGO. 29) Arterial calcification usually develops in the intima or the media of muscular-type arteries, 30,31) and may take more time to manifest clinically. Diabetic microangiopathy also progresses at a much slower rate.…”

Section: Discussionmentioning

confidence: 99%

Determinants of the Change in Arterial Stiffness in Peritoneal Dialysis Patients

et al. 2017

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SummaryArterial stiffness is an important risk factor for cardiovascular disease (CVD) in patients with end-stage renal failure. However, little is known about the factors that contribute to arterial rigidity in peritoneal dialysis (PD) patients. The aim of this study was to define the pattern and determinants of the longitudinal change in arterial stiffness after PD initiation.Arterial stiffening was estimated for 46 PD patients by using brachial-ankle pulse wave velocity (baPWV) and carotid intima-media thickness (cIMT). The cross-sectional relationship between the arterial markers and their clinical determinants was studied. The longitudinal effects of blood pressure (BP), body fluid status, and glucose were studied over the two years after initiating PD.Multivariate analysis showed that higher baPWV was associated positively with urinary protein excretion (P < 0.001), systolic BP (P = 0.001), and hemoglobin A1c (P = 0.003). In contrast, increased cIMT correlated with smoking (P = 0.004) and hypoalbuminemia (P = 0.04), suggesting that endothelial dysfunction is implicated in the atherogenic process. Neither cIMT nor baPWV correlated significantly with other PD-related covariates of volume overload, peritoneal solute transport, kidney function, and C-reactive protein. Longitudinal observation demonstrated that BP had a greater influence on baPWV changes than hyperglycemia or fluid status.Our study indicates that 1) baPWV represent an arterial marker that integrates multifactorial interaction between modifiable variables including BP and plasma glucose; and 2) intervention aimed at controlling BP as well as nutritional conditions (glucose and albumin) may reduce CVD risk in PD patients. (Int Heart J 2017; 58: 915-925)

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Section: Discussionmentioning

confidence: 99%

Determinants of the Change in Arterial Stiffness in Peritoneal Dialysis Patients

et al. 2017

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“… 4 – 6 An OFDI image of a calcified thrombus has been previously shown to present as a protruding mass with OFDI-signal backscattering and attenuation. 7 Furthermore, if it was an intracoronary embolus, this mobile mass could be embolized more distally or moved distally with injection of contrast. Moreover, there was no evidence of paroxysmal atrial fibrillation, which is a major cause of intracoronary embolization.…”

Section: Discussionmentioning

confidence: 99%

A case with a large intracoronary mobile mass diagnosed with a calcified thrombus using optical frequency domain imaging and intravascular ultrasound

Kuno

Hashimoto

Imaeda

et al. 2017

SAGE Open Medical Case Reports

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Objectives:A calcified thrombus is rare, but needs to be recognized and to be differentiated from calcified nodule.Methods:We report a case of acute coronary syndrome and a large intracoronary mobile mass, which was identified as a calcified thrombus by optical frequency domain imaging and intravascular ultrasound.Results:Successful direct stenting indicated that mobile mass was a calcified thrombus, not a calcified nodule.Conclusions:Cardiologists should be aware that an intracoronary mobile mass could be a calcified thrombus. This diagnosis can be confirmed through the combined use of optical frequency domain imaging and intravascular ultrasound.

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“…Koga et al опубликовали клинический случай, когда у пациентки, получавшей гемодиализ, визуализировали кальцинированный тромб in vivo с помощью ОКТ, ВСУЗИ и ангиоскопии. Авторы не указали, какой раствор применялся для создания оптически прозрачной среды [36]. Ozaki et al провели исследование 25 стентированных сегментов у 22 пациентов.…”

Section: Intravascular Imaging Of Atherosclerotic Plaques In Patientsunclassified

Intravascular imaging of atherosclerotic plaques in patients with cardiorenal syndrome: potential use of optical coherence tomography

Sozykin¹,

Шевченко²,

Наумов³

et al. 2020

RJTAO

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Currently, kidney transplantation and hemodialysis are the primary therapies for end-stage renal disease. High mortality, mostly caused by cardiovascular disease, remains the main challenge in the treatment of this category of patients. It has been shown that in patients with end-stage chronic kidney disease undergoing hemodialysis, the risk of mortality due to cardiovascular disease is up to 20 times higher than in the sex- and age-matched general population. The indicated data determined the appropriateness of isolating cardiorenal relationships into a single cardiorenal syndrome (CRS). Due to the facts mentioned above, intravascular imaging methods, notably optical coherence tomography (OCT), are particularly important in diagnosing coronary artery lesions. This review analyses the data published to date on the features and capabilities of OCT in CRS patients.

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Diverse Findings in Calcified Thrombus Between Histopathology and <i>In Vivo</i> Imaging Including Intravascular Ultrasound, Optical Coherence Tomography, and Angioscopy

Cited by 7 publications

References 16 publications

Determinants of the Change in Arterial Stiffness in Peritoneal Dialysis Patients

Determinants of the Change in Arterial Stiffness in Peritoneal Dialysis Patients

A case with a large intracoronary mobile mass diagnosed with a calcified thrombus using optical frequency domain imaging and intravascular ultrasound

Intravascular imaging of atherosclerotic plaques in patients with cardiorenal syndrome: potential use of optical coherence tomography

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