Diversity of gammacoronaviruses and deltacoronaviruses in wild birds and poultry in Russia

Marchenko, Vasiliy Y.; Danilenko, Alexey V.; Kolosova, N. G.; Bragina, Maria; Molchanova, Marina S.; Bulanovich, Yuliya; Gorodov, Vladimir; Leonov, Sergey B.; Gudymo, Andrey S.; Onkhonova, Galina; Svyatchenko, Svetlana V.; Ryzhikov, Alexander B.

doi:10.1038/s41598-022-23925-z

Cited by 15 publications

(10 citation statements)

References 44 publications

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“…The discovery of tursanvit virus 1 (TURSV-1) in walleye, represents (to our knowledge) the first such gammacoronavirus identified in fish. TURSV-1 is most closely related to infectious bronchitis virus (IBV), exemplar member of the subgenus Igacovirus , all of which infect birds [ 84 , 85 ]. IBV, predominantly a pathogen of chickens, affects the respiratory tract, gastrointestinal tract, kidney and reproductive systems of poultry, which has led to economic losses within the industry [ 46 ].…”

Section: Discussionmentioning

confidence: 99%

Five Species of Wild Freshwater Sport Fish in Wisconsin, USA, Reveal Highly Diverse Viromes

Ford,

Dunn,

Leis

et al. 2024

Pathogens

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Studies of marine fish have revealed distant relatives of viruses important to global fish and animal health, but few such studies exist for freshwater fish. To investigate whether freshwater fish also host such viruses, we characterized the viromes of five wild species of freshwater fish in Wisconsin, USA: bluegill (Lepomis macrochirus), brown trout (Salmo trutta), lake sturgeon (Acipenser fulvescens), northern pike (Esox lucius), and walleye (Sander vitreus). We analyzed 103 blood serum samples collected during a state-wide survey from 2016 to 2020 and used a metagenomic approach for virus detection to identify known and previously uncharacterized virus sequences. We then characterized viruses phylogenetically and quantified prevalence, richness, and relative abundance for each virus. Within these viromes, we identified 19 viruses from 11 viral families: Amnoonviridae, Circoviridae, Coronaviridae, Hepadnaviridae, Peribunyaviridae, Picobirnaviridae, Picornaviridae, Matonaviridae, Narnaviridae, Nudnaviridae, and Spinareoviridae, 17 of which were previously undescribed. Among these viruses was the first fish-associated coronavirus from the Gammacoronavirus genus, which was present in 11/15 (73%) of S. vitreus. These results demonstrate that, similar to marine fish, freshwater fish also harbor diverse relatives of viruses important to the health of fish and other animals, although it currently remains unknown what effect, if any, the viruses we identified may have on fish health.

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Section: Discussionmentioning

confidence: 99%

Five Species of Wild Freshwater Sport Fish in Wisconsin, USA, Reveal Highly Diverse Viromes

Ford,

Dunn,

Leis

et al. 2024

Pathogens

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“…We aimed to show whether we could detect different viruses in our samples, rather than compare the impact of the methods employed on the results. The 2022 study by Marchenko et al of samples taken from wild waterfowl of the Novosibirsk region revealed only one deltacoronavirus in a Gadwall collected in 2020, while the phylogeny of gammacoronaviruses and their hosts were revealed as miscellaneous [ 23 ]. Nevertheless, similar studies in wintering sites in China revealed a large prevalence of deltacoronaviruses [ 32 ].…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…A vast area containing wild bird breeding sites in Russia remained untested for ACoV until our study and two independent investigations were carried out [ 23 , 24 ]. Research conducted in 2020 provided data on the presence of wild bird coronaviruses in 14 regions of Russia [ 23 ], while early study of Beringia area in 2010 revealed ACoVs in geese, ducks, and shorebirds [ 24 ]. Our study provides data on the presence of coronaviruses among wild birds in two observational sites in Russia in 2021, which represent two most significant key points among the breeding sites of birds using two principal Eurasian flyways.…”

Section: Introductionmentioning

confidence: 99%

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Does Avian Coronavirus Co-Circulate with Avian Paramyxovirus and Avian Influenza Virus in Wild Ducks in Siberia?

Sharshov

Dubovitskiy

Derko

et al. 2023

Viruses

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Avian coronaviruses (ACoV) have been shown to be highly prevalent in wild bird populations. More work on avian coronavirus detection and diversity estimation is needed for the breeding territories of migrating birds, where the high diversity and high prevalence of Orthomyxoviridae and Paramyxoviridae have already been shown in wild birds. In order to detect ACoV RNA, we conducted PCR diagnostics of cloacal swab samples from birds, which we monitored during avian influenza A virus surveillance activities. Samples from two distant Asian regions of Russia (Sakhalin region and Novosibirsk region) were tested. Amplified fragments of the RNA-dependent RNA-polymerase (RdRp) of positive samples were partially sequenced to determine the species of Coronaviridae represented. The study revealed a high presence of ACoV among wild birds in Russia. Moreover, there was a high presence of birds co-infected with avian coronavirus, avian influenza virus, and avian paramyxovirus. We found one case of triple co-infection in a Northern Pintail (Anas acuta). Phylogenetic analysis revealed the circulation of a Gammacoronavirus species. A Deltacoronavirus species was not detected, which supports the data regarding the low prevalence of deltacoronaviruses among surveyed bird species.

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“…Alpha- and beta-coronaviruses (beta-CoV) typically infect mammals and can cause anything from the common cold to severe and fatal diseases, with respiratory and gastroenteritis symptoms [ 24 ]. On the other hand, gamma- and delta-coronaviruses primarily infect birds but can also infect other animals [ 25 ]. Avian coronaviruses often rapidly evolve and adapt to animals before making a species jump to humans [ 26 ].…”

Section: Coronavirus Infection and Their Strain Variationmentioning

confidence: 99%

Exigency of Plant-Based Vaccine against COVID-19 Emergence as Pandemic Preparedness

2023

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After two years since the declaration of COVID-19 as a pandemic by the World Health Organization (WHO), more than six million deaths have occurred due to SARS-CoV-2, leading to an unprecedented disruption of the global economy. Fortunately, within a year, a wide range of vaccines, including pathogen-based inactivated and live-attenuated vaccines, replicating and non-replicating vector-based vaccines, nucleic acid (DNA and mRNA)-based vaccines, and protein-based subunit and virus-like particle (VLP)-based vaccines, have been developed to mitigate the severe impacts of the COVID-19 pandemic. These vaccines have proven highly effective in reducing the severity of illness and preventing deaths. However, the availability and supply of COVID-19 vaccines have become an issue due to the prioritization of vaccine distribution in most countries. Additionally, as the virus continues to mutate and spread, questions have arisen regarding the effectiveness of vaccines against new strains of SARS-CoV-2 that can evade host immunity. The urgent need for booster doses to enhance immunity has been recognized. The scarcity of “safe and effective” vaccines has exacerbated global inequalities in terms of vaccine coverage. The development of COVID-19 vaccines has fallen short of the expectations set forth in 2020 and 2021. Furthermore, the equitable distribution of vaccines at the global and national levels remains a challenge, particularly in developing countries. In such circumstances, the exigency of plant virus-based vaccines has become apparent as a means to overcome supply shortages through fast manufacturing processes and to enable quick and convenient distribution to millions of people without the reliance on a cold chain system. Moreover, plant virus-based vaccines have demonstrated both safety and efficacy in eliciting robust cellular immunogenicity against COVID-19 pathogens. This review aims to shed light on the advantages and disadvantages of different types of vaccines developed against SARS-CoV-2 and provide an update on the current status of plant-based vaccines in the fight against the COVID-19 pandemic.

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Diversity of gammacoronaviruses and deltacoronaviruses in wild birds and poultry in Russia

Cited by 15 publications

References 44 publications

Five Species of Wild Freshwater Sport Fish in Wisconsin, USA, Reveal Highly Diverse Viromes

Five Species of Wild Freshwater Sport Fish in Wisconsin, USA, Reveal Highly Diverse Viromes

Does Avian Coronavirus Co-Circulate with Avian Paramyxovirus and Avian Influenza Virus in Wild Ducks in Siberia?

Exigency of Plant-Based Vaccine against COVID-19 Emergence as Pandemic Preparedness

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