DNA nanotechnology and bioassay development

A cooperation tale of biomolecules and nanomaterials in nanoscale chiral sensing and separation

“…Owing to the high predictability and programmability of oligonucleotides, DNA provides a favorable scaffold for nanoscale fabrication. [19][20][21][22][23][24][25] A nearly infinite amount of sequences enable synthetic DNA nanostructures to far surpass what nature has constructed with DNA. DNA technology has been revolutionary in our ability to regulate molecular selfassembly.…”

DNA tile self-assembly driven by antibody-mediated four-way branch migration

“…6 With respect to structural DNA nanotechnology, in 1982, Seeman 7 proposed the formation of migrationally immobile junctions by hybridizing oligonucleotide sequences and indicated that they may generate three-dimensional networks of nucleic acids, which was an important breakthrough in the field of DNA nanotechnology. Since then, structural DNA nanotechnology has used "bottom-up" self-assembly technology 8 to construct a variety of complex two-dimensional and threedimensional DNA nanostructures, such as tiles, 9,10 DNA bricks, 11 and origami. 12,13 This enables structural DNA nanotechnology to be widely used in nanomachines, 14,15 DNA computing, 16,17 information storage, [18][19][20][21] biomedicine, [22][23][24] and other fields.…”

Smart and Functionalized Development of Nucleic Acid‐Based Hydrogels: Assembly Strategies, Recent Advances, and Challenges

“…Accordingly, a series of novel materials have emerged, based on DNA assembly, such as DNA origami, nanoparticle–DNA colloidal materials, and polymer–DNA materials. [ 1 , 4 ] These products possess unique DNA nanostructures and molecular properties and are integrated with other polymers and nanomaterials to meet the developmental demand for DNA nanotechnology and applications in material engineering.…”