DNA oxidation mediated by [Ru(bpy)2tatp]2+ upon incorporation of [Co(phen)3]3+

Xu, Shidang; Lu, Chunjie; Shao, Jiang‐Yang; Li, Qian; Li, Hong; Li, Weishan

doi:10.1016/j.jelechem.2011.07.047

Cited by 4 publications

(2 citation statements)

References 44 publications

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“…The non-covalent interactions of the tris-(1,10-phenanthroline)-Co(III) complex with DNA, demonstrated through cyclic voltammetry, has motived different research groups to develop new electrochemical biosensors based on DNA hybridization. Detection of human immunodeficiency virus (HIV), Escherichia coli, Hepatitis B virus and the chemotherapeutic agent for lymphoblastic leukemia, 6-Mercaptopurine, are some examples of these biosensors [19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35].…”

Section: Introductionmentioning

confidence: 99%

The Role of the π Acceptor Character of Polypyridine Ligands on the Electrochemical Response of Co(II) Complexes and its Effect on the Homogenous Electron Transfer Rate Constant with the Enzyme Glucose Oxidase

Ramírez-Delgado¹,

Cruz-Ramírez²,

Hernández‐Ayala

et al. 2017

J. Mex. Chem. Soc.

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In this work the electrochemical behavior of Co(II) com-plexes with substituted bidentate and tridentate polypyridine ligands [CoL3](BF4)2 and [CoL´2](NO3)2 in 0.1M phosphate buffer pH 7.2 was studied. A reversible electrochemical process Co(II)Ln → Co(III) Ln +1eˉ was observed. A linear relationship between the redox poten-tial (E°) and the pKa of the non-coordinated ligand was found. It was demonstrated by DFT calculations the use of pKa value as a descriptor of the π acceptor character of a ligand. The electrochemical response in the presence of glucose oxidase (GOx) was also studied. It was pos-sible to establish a tendency between the homogeneous electron trans-fer rate constant (ks) and the redox potential (E°) for the compounds studied in this work and other examples taken from the literature.

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Section: Introductionmentioning

confidence: 99%

The Role of the π Acceptor Character of Polypyridine Ligands on the Electrochemical Response of Co(II) Complexes and its Effect on the Homogenous Electron Transfer Rate Constant with the Enzyme Glucose Oxidase

Ramírez-Delgado¹,

Cruz-Ramírez²,

Hernández‐Ayala

et al. 2017

J. Mex. Chem. Soc.

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“…Thus, phenanthroline complexes of copper , cobalt , and bipyridine complex of Ru promote oxidation of guanine/adenine residues resulted in alteration of the mediator signals. DNA oxidation affects the affinity of Co phenanthroline and Methylene blue (MB) toward native DNA and remarkably changes their redox signals . The significant attention paid to most redox active DNA intercalators is due to their specific interaction with the DNA helix that improves the selectivity of the signal.…”

Section: Introductionmentioning

confidence: 99%

Voltammetric Detection of Oxidative DNA Damage Based on Interactions between Polymeric Dyes and DNA

et al. 2016

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Oxidative damage of DNA was assessed with glassy carbon electrode (GCE) coated with electropolymerized Methylene Blue (MB). For this purpose, DNA solution was first mixed with an oxidant (Fenton reagent, H2O2 alone and in the presence of Cu(II) ions) and then placed on the polymeric film surface. After washing, the cyclic voltammogram was recorded in buffer solution and the anodic peak potential measured against that before the contact with DNA. Oxidative DNA damage resulted in remarkable decrease of the anodic peak potential which depended on the oxidant nature and incubation period. Specificity of the DNA – MB interactions was confirmed by surface plasmon resonance (SPR) measurements. Similar experiment performed with polymerized Methylene Green (MG) and Neutral Red (NR) showed lower selectivity of the response toward various sources of reactive oxygen species. The protocol of the DNA damage detection was tested on the estimation of antioxidant properties of green tea extract and red table wine.

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Biosensor to Ensure Food Security and Environmental Control

Evtugyn

2016

Biosensors for Sustainable Food - New Opportunities and Technical Challenges

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DNA oxidation mediated by [Ru(bpy)2tatp]2+ upon incorporation of [Co(phen)3]3+

Cited by 4 publications

References 44 publications

The Role of the π Acceptor Character of Polypyridine Ligands on the Electrochemical Response of Co(II) Complexes and its Effect on the Homogenous Electron Transfer Rate Constant with the Enzyme Glucose Oxidase

The Role of the π Acceptor Character of Polypyridine Ligands on the Electrochemical Response of Co(II) Complexes and its Effect on the Homogenous Electron Transfer Rate Constant with the Enzyme Glucose Oxidase

Voltammetric Detection of Oxidative DNA Damage Based on Interactions between Polymeric Dyes and DNA

Biosensor to Ensure Food Security and Environmental Control

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