DNA‐Templated Photonic Arrays and Assemblies: Design Principles and Future Opportunities

Wu, Songhua; Bonnard, Vanessa; Burley, Glenn A.

doi:10.1002/chem.201100924

Cited by 58 publications

(33 citation statements)

References 83 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[18][19][20][21][22][23][24] Moreover, the predictable secondary structure, unique binding sites for small molecules and the ability to control the spatial arrangement of chromophores with nanoscale precision make DNA an excellent scaffold for related applications in optoelectronic devices and sensors. [33][34][35][36][37][38][39][40][41][42][43][44] While many groups have used the interaction of chromophores with DNA in demonstrating DNA mediated white light emission, [18][19][20][21][22][23]45 there exists need for fundamental understanding on the structure-property correlation controlling the output of the light emission. 27,[29][30][31][32][33] This in turn is regulated by apparent binding constants and allosteric factors when multiple chromophores are involved.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous binding of a cyclophane and classical intercalators to DNA: observation of FRET-mediated white light emission

Sanju

Thurakkal

Neelakandan

et al. 2015

Phys. Chem. Chem. Phys.

View full text Add to dashboard Cite

DNA-assisted Förster resonance energy transfer (FRET) between an anthracene-based cyclophane (CP) and mono- and bis-intercalators such as propidium iodide (PI) and ethidium homodimer-1 (EHD), respectively, has been studied using various photophysical and biophysical techniques. The cyclophane and PI exhibited simultaneous binding to DNA at all concentrations studied and showed DNA-assisted FRET from the excimer of cyclophane with a FRET efficiency of ca. 71%. On the other hand, the bis-intercalator EHD, only at lower concentrations (<3 μM), can act as an acceptor for the energy transfer process with a lower efficiency of ca. 44%. At higher concentrations (>15 μM), EHD, on account of its higher binding affinity, displaces cyclophane from the DNA scaffold. Employing the ternary system comprising of the cyclophane, DNA and PI and fine-tuning the concentrations of the components in a molar ratio of 1 : 0.75 : 0.05 (CP : DNA : PI) we have demonstrated white light emission with CIE coordinates (0.35, 0.37).

show abstract

Section: Introductionmentioning

confidence: 99%

Simultaneous binding of a cyclophane and classical intercalators to DNA: observation of FRET-mediated white light emission

Sanju

Thurakkal

Neelakandan

et al. 2015

Phys. Chem. Chem. Phys.

View full text Add to dashboard Cite

show abstract

“…Migration of energy onto a porphyrin chromophore precisely placed within a DNA nanostructure is of interest in terms of applications since such photoactive supramolecular complexes could lead to the development of self-assembled antenna structures for artificial light harvesting, 26 or singlet oxygen generation (e.g., with potential in light-activated antibacterial applications) 61 .In addition, there is a need for the identification of quadruplex DNA specific binding agents 62 , thus such nanostructured assemblies incorporating quadruplex DNA could lead to high-throughput surface-based sensing platforms that can detect quadruplex binding agents via the disruption of an energy-transfer process. 21 For instance, a small molecule or protein that binds to the quadruplex domain and displaces the dye will lead to loss of energy transfer to the porphyrin and thus can be detected.…”

Section: Discussionmentioning

confidence: 99%

Photonic DNA-Chromophore Nanowire Networks: Harnessing Multiple Supramolecular Assembly Modes

et al. 2013

View full text Add to dashboard Cite

Photonic DNA nanostructures are typically prepared by the assembly of multiple sequences of long DNA strands that are conjugated covalently to various dye molecules. Herein we introduce a non-covalent method for the construction of porphyrin-containing DNA nanowires and their networks that uses the programmed assembly of a single, very short, oligodeoxyribonucleotide sequence. Specifically, our strategy exploits a number of supramolecular binding modalities (including DNA base-pairing, metal-ion coordination, and β-cyclodextrin-adamantane derived host-guest interactions) for simultaneous nanowire assembly and porphyrin incorporation. Furthermore, we also show that the resultant DNA-porphyrin assembly can be further functionalized with a complementary “off-the-shelf” DNA binding dye resulting in photonic structures with broadband absorption and energy transfer capabilities.

show abstract

“…A recent article on DNA-templated photonic arrays and assemblies by Su et al 37 provides an excellent analysis of the different approaches and outlooks for this concept. The intercalation of energy relay dye molecules into DNA and the use of DNA minor groove binders are two important methods for assembling the photonic arrays on dsDNA templates.…”

Section: Fluorescence Of Dye-doped Dnasmentioning

confidence: 99%

Optical, electro-optic and optoelectronic properties of natural and chemically modified DNAs

Kwon

Choi

Jin

2012

Polym J

View full text Add to dashboard Cite

This article reviews recent findings on the optical, electro-optic and optoelectronic properties of natural and modified DNAs. When the sodium (Na þ ) ions of DNA are replaced with long alkyl quaternary ammonium (Q þ ) ions, the resulting compositions (Q þ DNA À ) are organic-soluble, and thin films produced using these materials reveal many interesting optical and optoelectronic properties. These films tend to form well-structured supramolecular assemblies. In contrast, natural DNAs are water-soluble and hygroscopic. DNAs are strong absorbers of UV wavelengths in the region of 260 nm. The Q þ DNA À films are excellent dielectrics that can be utilized as insulating layers in organic thin film transistors. Chemical modification of the Q þ parts results in many interesting structures that can be used in a wide variety of optical and optoelectronic devices. This review specifically deals with the optical and fluorescence properties of, organic lasing composites, the nonlinear optical characteristics of, light-emitting diodes, and photovoltaic cells based on natural and modified DNAs.

show abstract

DNA‐Templated Photonic Arrays and Assemblies: Design Principles and Future Opportunities

Cited by 58 publications

References 83 publications

Simultaneous binding of a cyclophane and classical intercalators to DNA: observation of FRET-mediated white light emission

Simultaneous binding of a cyclophane and classical intercalators to DNA: observation of FRET-mediated white light emission

Photonic DNA-Chromophore Nanowire Networks: Harnessing Multiple Supramolecular Assembly Modes

Optical, electro-optic and optoelectronic properties of natural and chemically modified DNAs

Contact Info

Product

Resources

About