Dobutamine echocardiography and resting-redistribution thallium-201 scintigraphy predicts recovery of hibernating myocardium after coronary revascularization

Charney, Richard; Schwinger, Matthew E.; Chun, Jenny; Cohen, Michael V.; Nanna, Michele; Menegus, Mark; Wexler, John; Franco, Hugo Spindola; Greenberg, Mark A.

doi:10.1016/0002-8703(94)90581-9

Cited by 114 publications

(20 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…3,4,17 Combined analysis of these studies yielded negative and positive predictive values of 92% and 69%, respectively. 5 Thus, a substantial number of patients with rest 201 Tl reversibility do not demonstrate improvement in function after revascularization.…”

Section: Prediction Of Recovery Of Myocardial Dysfunctionmentioning

confidence: 98%

Incremental Prognostic Value of Rest-Redistribution ²⁰¹ Tl Single-Photon Emission Computed Tomography

Sharir

Berman²,

Lewin³

et al. 1999

Circulation

View full text Add to dashboard Cite

Background-The incremental prognostic value of rest-redistribution 201 Tl compared with stress and rest perfusion abnormalities has not been defined. Methods and Results-We identified 458 patients who underwent rest 201 Tl /stress (exercise or adenosine) 99m Tc sestamibi single-photon emission computed tomography (SPECT) and had late (18 to 24 hours) 201 Tl imaging, were not revascularized within 60 days of SPECT, and were followed up at Ͼ1 year. SPECT images were visually analyzed with the use of a 20-segment model on a scale of 0 to 4. Thirty-seven cardiac deaths (CDs) and 17 nonfatal myocardial infarctions occurred. Univariate Cox proportional hazards analysis showed that the presence of a large amount of rest

show abstract

Section: Prediction Of Recovery Of Myocardial Dysfunctionmentioning

confidence: 98%

Incremental Prognostic Value of Rest-Redistribution ²⁰¹ Tl Single-Photon Emission Computed Tomography

Sharir

Berman²,

Lewin³

et al. 1999

Circulation

View full text Add to dashboard Cite

show abstract

“…[50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][66][67] The lower specificity of nuclear imaging can again be an issue of duration of follow-up. Recent data have demonstrated that a substantial percentage of segments need longer time after revascularisation to (fully) recover in function.…”

Section: Figmentioning

confidence: 99%

Noninvasive evaluation of ischaemic heart disease: myocardial perfusion imaging or stress echocardiography?

Schinkel

Bax

Geleijnse

et al. 2003

European Heart Journal

159

View full text Add to dashboard Cite

“…Although earlier investigations comparing dobutamine echocardiography with perfusion scintigraphy23 24 and involving a small number of patients showed comparable results, differences in specificity for recovery of function have been more recently reported 1011 Hibernating myocardium is defined by its ability to recover function with restoration of adequate perfusion.…”

Section: Discussionmentioning

confidence: 99%

Concordance between dobutamine Doppler tissue imaging echocardiography and rest reinjection thallium-201 tomography in dysfunctional hypoperfused myocardium

Larrazet

Pellerin

Daou

et al. 1999

Heart

View full text Add to dashboard Cite

Objective-To evaluate the eYciency of the new technique colour Doppler tissue imaging (DTI) by studying the concordance between dobutamine DTI, standard grey scale echocardiography (SE), and rest-reinjection TI-201 tomography (TI) in dysfunctional myocardium. Patients-23 patients with chronic wall motion abnormalities and proven coronary artery disease (> 70% diameter stenosis of at least one major coronary artery at angiogram). Methods-The contractile reserve and the resting perfusion characteristics of dysfunctional myocardial segments were assessed with low dose dobutamine SE and/or DTI (2.5 up to 20 /kg/min) and TI on a semiquantitative basis. The DTI or SE data were separately compared with TI, on the basis of a 13 segment ventricular model. The resulting score of combined DTI and SE was also compared with TI. Finally the results obtained from DTI were compared with SE. Results-A total of 142 severely hypokinetic or akinetic segments were visualised. The viability study was feasible in 127 (89%) and 121 (85%) segments with DTI and SE, respectively. TI detected viability more frequently than DTI (84 v 61, p < 0.001) and SE (80 v 50, p < 0.001). However, as many viable segments were detected with combined DTI and SE as with TI (78 v 84, NS). The values between TI and SE, DTI or combined SE and DTI were 0.38, 0.45, and 0.57, respectively, and increased to 0.52 and 0.76, respectively, for SE and DTI versus TI when mid-anterior and mid-inferior segments only were considered. The value between SE and DTI was 0.34. Conclusions-DTI is a helpful adjunct to SE, when using low dose dobutamine. This combination revealed as many viable segments as TI and showed a better agreement than DTI or SE alone for the assessment of myocardial viable segments evidenced by TI. (Heart 1999;82:432-437) Keywords: colour Doppler tissue imaging; hibernating myocardium; thallium 201 single photon emission computed tomography; stress echocardiography Stress echocardiography is currently performed to detect hibernating myocardium in patients suVering from chronic coronary artery disease. [1][2][3][4][5] Other techniques such as thallium-201 reinjection tomography (TI) and positron emission tomography might oVer a good prediction of contractility recovery after myocardial reperfusion or revascularisation.5-8 High concordance between stress echocardiography or TI and positron emission tomography was observed in studies involving small series of patients.8 9 Two previous studies comparing standard echocardiography (SE) and TI paradoxically showed discordances in the specificity for recovery of function. 11Doppler tissue imaging (DTI) was introduced with the hope to give a quantitative echocardiographic approach to myocardial wall velocities and to minimise the subjectivity of SE assessment of ventricular function.12-19 A visual semiquantitative evaluation of dobutamine on DTI colour images versus grey scale echocardiography has been recently reported, but no reference method was used. 20To test the eYciency of this new technique we...

show abstract

Dobutamine echocardiography and resting-redistribution thallium-201 scintigraphy predicts recovery of hibernating myocardium after coronary revascularization

Cited by 114 publications

References 24 publications

Incremental Prognostic Value of Rest-Redistribution ²⁰¹ Tl Single-Photon Emission Computed Tomography

Incremental Prognostic Value of Rest-Redistribution ²⁰¹ Tl Single-Photon Emission Computed Tomography

Noninvasive evaluation of ischaemic heart disease: myocardial perfusion imaging or stress echocardiography?

Concordance between dobutamine Doppler tissue imaging echocardiography and rest reinjection thallium-201 tomography in dysfunctional hypoperfused myocardium

Contact Info

Product

Resources

About

Dobutamine echocardiography and resting-redistribution thallium-201 scintigraphy predicts recovery of hibernating myocardium after coronary revascularization

Cited by 114 publications

References 24 publications

Incremental Prognostic Value of Rest-Redistribution 201 Tl Single-Photon Emission Computed Tomography

Incremental Prognostic Value of Rest-Redistribution 201 Tl Single-Photon Emission Computed Tomography

Noninvasive evaluation of ischaemic heart disease: myocardial perfusion imaging or stress echocardiography?

Concordance between dobutamine Doppler tissue imaging echocardiography and rest reinjection thallium-201 tomography in dysfunctional hypoperfused myocardium

Contact Info

Product

Resources

About

Incremental Prognostic Value of Rest-Redistribution ²⁰¹ Tl Single-Photon Emission Computed Tomography

Incremental Prognostic Value of Rest-Redistribution ²⁰¹ Tl Single-Photon Emission Computed Tomography