Doença de Rosai-Dorfman como diagnóstico diferencial de lesão ulcerada de prega vocal

KEY WORDSRosai-Dorfman disease, sinus histiocytosis, lymphadenopathy, ultrasonography Rosai-Dorfman disease (RDD) is a rare and benign histiocytic proliferative disorder of unknown etiology. It can affect all age groups, particularly young adults. The typical clinical manifestation is painless, bilateral, massive cervical lymphadenopathy with or without extra nodal involvement, along with fever, weight loss, and night sweats. However, thyroid involvement is very uncommon. The ultrasonographic manifestations of RDD are rarely reported. A case of RDD involving the thyroid that was recorded in our hospital PACS system during 2002e2010 is reported here, which was initially misdiagnosed as non-Hodgkin's lymphoma (NHL). In our case, ultrasonography revealed diffuse enlargement of whole thyroid glands with heterogeneous hypoechogenicity. Areas of linear hyperechogenicity were noted on the sonograms with multiple enlarged nodes over the cervical, supraclavicular, and submandibular areas. Though not specific, in order to avoid unnecessary surgery or a total thyroidectomy, ultrasonography and ultrasonographyguided core needle biopsy should be performed to establish an accurate diagnosis. ª

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Rosai-Dorfman Disease with Isolated Laryngeal Involvement

Illing

Halum

2012

Ear Nose Throat J

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Rosal-Dorfman disease is a rare histiocyte disorder that is typically characterized by massive cervicallymphadenopathy. Isolated extranodal involvement is uncommon, and isolated laryngeal involvement isextremely rare. We report an unusual case of Rosai-Dorfman disease with isolated laryngeal involvement that led to recurrent dysphonia andairway obstruction. Wediscuss thechallenges wefacedin reaching a correctpathologic diagnosis and in deciding on an appropriate treatment regimen. Based on our experience, we believe that Rosai-Dorfman disease shouldbeconsidered asadifferential diagnosis inpatients whopresent with a recurrent inflammatory (histiocytic) masslesion of the larynx.

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Doença de Rosai-Dorfman como diagnóstico diferencial de lesão ulcerada de prega vocal

Cited by 5 publications

References 6 publications

Larynx and Hypopharynx

Larynx and Hypopharynx

Sonographic Manifestation of Thyroid's Rosai-Dorfman Disease

Rosai-Dorfman Disease with Isolated Laryngeal Involvement

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