Does adherence to the Mediterranean dietary pattern reduce asthma symptoms in children? A systematic review of observational studies

Papamichael, Maria Michelle; Itsiopoulos, Catherine; Susanto, Nugroho Harry; Erbas, Bircan

doi:10.1017/s1368980017001823

Cited by 48 publications

(48 citation statements)

References 51 publications

(212 reference statements)

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“…Four systematic reviews focussing on nutrients and foods associated with asthma and allergy outcomes investigated the impact of the Mediterranean diet in childhood and found an inverse relationship between eating according to the Mediterranean diet and a range of reported symptoms such as wheeze and asthma. Papamichael et al summarized twelve studies reporting an inverse association between adherence to a Mediterranean dietary pattern and asthma in children. Nurmatov et al reported that adherence to a Mediterranean diet was protective for persistent wheeze (OR, 0.22; 95% CI, 0.08‐0.58) and atopy (OR, 0.55; 95% CI, 0.31‐0.97).…”

Section: Methodsmentioning

confidence: 99%

“…While this is an important relationship to understand, no studies have been identified exploring an association between the Mediterranean diet in infancy and allergy outcomes. Four systematic reviews focussing on nutrients and foods associated with asthma and allergy outcomes investigated the impact of the Mediterranean diet in childhood [101][102][103][104] Ten original papers were also identified ( 97 and allergic rhinitis. 94,98,105 However, as with the maternal studies, none of the studies focused on food allergy as an outcome.…”

Section: Mediterranean Diet In Infancy and Childhoodmentioning

confidence: 99%

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EAACI position paper on diet diversity in pregnancy, infancy and childhood: Novel concepts and implications for studies in allergy and asthma

Venter

Greenhawt

Meyer

et al. 2020

Allergy

123

141

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To fully understand the role of diet diversity on allergy outcomes and to set standards for conducting research in this field, the European Academy of Allergy and Clinical Immunology Task Force on Diet and Immunomodulation has systematically explored the association between diet diversity and allergy outcomes. In addition, a detailed narrative review of information on diet quality and diet patterns as they pertain to allergic outcomes is presented. Overall, we recommend that infants of any risk category for allergic disease should have a diverse diet, given no evidence of harm and some potential association of benefit in the prevention of particular allergic outcomes. In order to harmonize methods for future data collection and reporting, the task force members propose relevant definitions and important factors for consideration, when measuring diet diversity in the context of allergy. Consensus was achieved on practice points through the Delphi method. It is hoped that the definitions and considerations described herein will also enable better comparison of future studies and improve mechanistic studies and pathway analysis to understand how diet diversity modulates allergic outcomes.

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Section: Methodsmentioning

confidence: 99%

Section: Mediterranean Diet In Infancy and Childhoodmentioning

confidence: 99%

EAACI position paper on diet diversity in pregnancy, infancy and childhood: Novel concepts and implications for studies in allergy and asthma

Venter

Greenhawt

Meyer

et al. 2020

Allergy

123

141

View full text Add to dashboard Cite

show abstract

“…In general, a diet that is high in fat, processed foods, sugar and salt has been shown to increase the prevalence and risk of asthma in children and adolescents . By contrast, the International Study of Allergies and Asthma in Childhood (ISAAC) showed that a regular intake of fruit, vegetables and fish, as well as adherence to the Mediterranean diet, has a prophylactic effect on asthma in children and adolescents . In particular, a lower prevalence of asthma was found in Mediterranean centres of Western Europe that share a common dietary pattern .…”

Section: Introductionmentioning

confidence: 99%

Efficacy of a Mediterranean diet supplemented with fatty fish in ameliorating inflammation in paediatric asthma: a randomised controlled trial

Papamichael

Katsardis

Lambert

et al. 2018

J Human Nutrition Diet

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How to cite this article Papamichael M.M., Katsardis Ch., Lambert K., Tsoukalas D., Koutsilieris M., Erbas B., Itsiopoulos C. (2019) Efficacy of a Mediterranean diet supplemented with fatty fish in ameliorating inflammation in paediatric asthma: a randomised controlled trial. J Hum Nutr Diet. 32,[185][186][187][188][189][190][191][192][193][194][195][196][197] .https://doi. AbstractBackground: Childhood asthma is the most common respiratory disorder worldwide, being associated with increased morbidity and a decreased quality of life. Omega-3 fatty acids have anti-inflammatory and immunomodulating properties; however, their efficacy in asthma is controversial. The present study aimed to examine the efficacy of a Mediterranean diet supplemented with a high omega-3 'fatty' fish intake in Greek asthmatic children.Methods: A single-centred, 6-month, parallel randomised controlled trial compared the consumption of a Mediterranean diet supplemented with two meals of 150 g of cooked fatty fish weekly (intervention) with the usual diet (control) with respect to pulmonary function in children (aged 5-12 years) with mild asthma. Pulmonary function was assessed using spirometry and bronchial inflammation by fractional exhaled nitric oxide analysis. Results: Sixty-four children (52% male, 48% female) successfully completed the trial. Fatty fish intake increased in the intervention group from 17 g day À1 at baseline to 46 g day À1 at 6 months (P < 0.001). In the unadjusted analysis, the effect of the intervention was of borderline significance (P = 0.06, b = À11.93; 95% confidence interval = À24.32 to 0.46). However, after adjusting for age, sex, body mass index and regular physical activity, a significant effect was observed (P = 0.04, b = À14.15 ppb; 95% confidence interval = À27.39 to À0.91). No difference was observed for spirometry, asthma control and quality of life scores. Conclusions: A Mediterranean diet supplemented with two fatty fish meals per week might be a potential strategy for reducing airway inflammation in childhood asthma. Future robust clinical trials are warranted to replicate and corroborate these findings.185

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“…Moreover, a reduced risk of wheeze was seen in offspring of mothers assuming a regular intake of olive oil during pregnancy and epidemiological evidence has shown that in children, regular consumption of olive oil is associated with lower prevalence of doctor‐diagnosed asthma . Several studies have concluded that a Mediterranean diet might contribute to reduce the prevalence and severity of asthma, in children and in adults, but the specific effect of olive oil on respiratory illness in adults has been seldom investigated in population‐based studies. Data regarding rhinitis are even less abundant, in particular when addressing adult populations …”

Section: Introductionmentioning

confidence: 99%

Dietary fats, olive oil and respiratory diseases in Italian adults: A population‐based study

Cazzoletti

Zanolin

Spelta

et al. 2019

Clin Experimental Allergy

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Background: Fat intake has been associated with respiratory diseases, with conflicting results.Objective: We studied the association between asthma and rhinitis with dietary fats, and their food sources in an Italian population.Methods: Clinical and nutritional information was collected for 871 subjects (aged 20-84) from the population-based multi-case-control study Genes Environment Interaction in Respiratory Diseases (GEIRD): 145 with current asthma (CA), 77 with past asthma (PA), 305 with rhinitis and 344 controls. Food intake was collected using the EPIC (European Investigation into Cancer and Nutrition) Food Frequency Questionnaire. The associations between fats and respiratory diseases were estimated by multinomial models. Fats and their dietary sources were analysed both as continuous variables and as quartiles. Results: Monounsaturated fatty acids and oleic acid were associated with a reduced risk of CA in both continuous (RRR = 0.68, 95%CI: 0.48; 0.96; RRR = 0.69; 95%CI: 0.49; 0.97, per 10 g, respectively) and per-quartile analyses (p for trend = 0.028 and 0.024, respectively). Olive oil was associated with a decreased risk of CA (RRR = 0.80; 95%CI: 0.65; 0.98 per 10 g). An increased risk of rhinitis was associated with moderate total fat and SFA intake.Conclusions: High dietary intakes of oleic acid and of olive oil are associated with a lower risk of asthma but not of rhinitis.

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Does adherence to the Mediterranean dietary pattern reduce asthma symptoms in children? A systematic review of observational studies

Cited by 48 publications

References 51 publications

EAACI position paper on diet diversity in pregnancy, infancy and childhood: Novel concepts and implications for studies in allergy and asthma

EAACI position paper on diet diversity in pregnancy, infancy and childhood: Novel concepts and implications for studies in allergy and asthma

Efficacy of a Mediterranean diet supplemented with fatty fish in ameliorating inflammation in paediatric asthma: a randomised controlled trial

Dietary fats, olive oil and respiratory diseases in Italian adults: A population‐based study

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