Does change in barometric pressure per given time at high altitude influence symptoms of acute mountain sickness on Mount Fuji? A pilot study

Abstract

Background Acute mountain sickness (AMS) is a common, transient condition characterized primarily by headaches, and it can also be associated with fatigue, dizziness, and nausea with vomiting. The symptoms of AMS are most pronounced after the first night spent at a new altitude. At sea level, changes in barometric pressure per given time have been associated with migraine headaches. We sought to investigate whether changes in barometric pressure, subjective sleep quality index, and other candidates contributed to the risk of developing AMS on Mount Fuji in Japan. Method We surveyed 353 trekkers who stayed overnight at a mountain lodge before summitting Mount Fuji. We collected information regarding sex, age, sleeping altitude at the hut, and perceived sleep quality index including sleep time. AMS was assessed with the Lake Louise Scoring system. Barometric pressure and ambient temperature were collected at the 5th station (2305 m) and at the summit (3776 m). Result The overall prevalence of AMS in our cohort was 41.4% (Lake Louise Score ≥ 3 with headache, n=146). Using logistic regression, three factors were combined to generate a robust model for determining the risk of AMS (with or without AMS). These included (1) Δ barometric pressure during ascent per hour, (2) sleepiness on rising, and (3) sleep refreshment assessed by perceived sleep quality index. Conclusion These results suggest that climbers who stay overnight at the lodge should keep a better physical condition of sleep, and would pay attention to information of barometric pressure condition to decrease their risk of AMS at the summit of Mount Fuji. Our observatory data indicated that an overnight staying in half way up to the summit does not necessarily reduce the AMS risk in both sexes and irrespective of age, at least, until 3776 m elevation.

Hypoxic-induced resting ventilatory and circulatory responses under multistep hypoxia is related to decline in peak aerobic capacity in hypoxia

“…Although high variance inflation factors (VIFs > 5) indicate multicollinearity [ 18 ], the VIFs were < 3 for all explanatory variables. To identify the optimal model containing the parameters to best explain the data, we performed model selection by backward stepwise elimination using Akaike Information Criterion based on our previous studies [ 19 , 20 ]. All statistical analyses were performed using R ver.…”

Hubungan Usia, Jenis Kelamin, Tingkat Pengetahuan, Aktivitas Fisik Dengan Kejadian Acute Mountain Sickness (Ams) Pada Pendaki Gunung

“…Hasil penelitian ini tidak sesuai dengan penelitian yang dilakukan oleh Hou et al, (2019) yang menunjukkan bahwa terdapat hubungan antara jenis kelamin dengan risiko AMS dengan nilai p-value 0,000. Tetapi hasil penelitian ini sesuai dengan penelitian yang dilakukan oleh Horiuchi et al, (2021) yang menunjukkan bahwa tidak terdapat hubungan antara jenis kelamin dengan gejala AMS.…”

Incidence and risk factors during ascent to Hoh Xil and the physiological responses before and after acclimatization: a cross-sectional study

“…It has been reported that exposure to the high-altitude environment may trigger the overactivation of the sympathetic nervous system and the compensatory mechanism of the circulorespiratory system, this results in a series of physiological changes such as heart rat, blood pressure, and saturation of pulse oxygen that help acclimate the body to harsh environmental conditions [3,4]. However, when these physiological changes fail to occur, it results in a series of nonspeci c clinical symptoms, including headache, dizziness, fatigue, insomnia, anorexia, nausea, and vomiting [5]. More seriously, a small number of patients may develop life-threatening highaltitude pulmonary edema (HAPE) or high-altitude cerebral edema (HACE) under severe conditions and need emergency medical care [6][7][8].…”