Does Coronary Artery Bypass Graft Surgery Improve Survival Among Patients With End-Stage Renal Disease?

Preoperative Chronic Kidney Disease as a Strong Predictor of Postoperative Infection and Mortality After Coronary Artery Bypass Grafting

“…Dewey et al showed that off-pump CABG improved the early mortality rate compared to on-pump CABG in HD patients, but longterm survival was better in the on-pump CABG group. 27 Also, Boulton et al showed that long-term survival was significantly lower in off-pump CABG in patients with mild to moderate CKD compared to that of on-pump CABG. 28 Surgeons should keep in mind that complete revascularization in patients undergoing CABG always yields a survival benefit.…”

Off-pump coronary bypass surgery for high-risk patients: only in expert centers?

“…In a prospective randomized trial of patients with preoperative renal insufficiency, Sajja et al [44] demonstrated that OPCAB was beneficial with decreased postoperative serum creatinine values and increased glomerular filtration rate compared to ONCAB. Dewey et al [45] showed improved operative mortality in favor of OPCAB among patients with dialysis-dependent renal failure; this early benefit, however, did not translate into improved longterm survival.…”

“…In multiple studies, OPCAB has been shown to reduce morbidity and mortality in patients with normal renal function [42,43], those with renal dysfunction not yet on hemodialysis [44] as well as those with end-stage renal failure on dialysis [45]. In a prospective randomized trial of patients with preoperative renal insufficiency, Sajja et al [44] demonstrated that OPCAB was beneficial with decreased postoperative serum creatinine values and increased glomerular filtration rate compared to ONCAB.…”

Off-pump coronary surgery: where do we stand in 2010?

“…Several retrospective studies have documented improved outcomes in higher-risk patients undergoing OPCAB. Dewey et al [23] showed improved operative mortality in favor of OPCAB among patients with dialysis-dependent renal failure. However, Shroff and colleagues [24 ] reported only a modestly increased survival advantage for OPCAB patients.…”