Does elastography reduce the need for thyroid <scp>FNA</scp>s?

Mehrotra, Pallavi; McQueen, Andrew; Kolla, SriDurgaDevi; Johnson, Sarah J.; Richardson, D. L.

doi:10.1111/cen.12077

Cited by 39 publications

(42 citation statements)

References 34 publications

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“…the identification of benign nodules [27,43], which is concordant with our results. Few reports are related to the usefulness of SEG in the nodules with an equivocal FNA result.…”

Section: Prace Oryginalnesupporting

confidence: 92%

“…This was because of differences in the elastographic image of cancers between FL and UC groups. These observations are concordant with some reports suggesting that the stiffness of PTCs may differ from the stiffness of other thyroid cancers (including FTC and MTC) on the basis of ES evaluation [19,27,43,44] or -less often -SR evaluation [45]. We did not find any differences between benign lesions in both groups.…”

Section: Prace Oryginalnesupporting

confidence: 92%

“…[20]. Interestingly, Mehrorta et al [43] showed that the ES measurement might be helpful in the selection of benign nodules only due to high NPV and SPC, but it was related to low PPV. Shuzhen [44] demonstrated higher NPV, SPC, and ACC but lower SEN for ES in comparison with UMRFs analysis.…”

Section: Discussionmentioning

confidence: 99%

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Porównanie skuteczności elastografii w diagnostyce zmian pęcherzykowych tarczycy i ognisk z jednoznacznym wynikiem BAC

Wojtaszek-Nowicka

Słowińska-Klencka

Sporny

et al. 2015

Endokrynologia Polska

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Introduction:The aim was to assess the usefulness of strain elastography (SEG) in the diagnostics of two groups of thyroid nodules (TNs): follicular lesions (FL) with low malignancy risk (< 20.0%) and low percentage of papillary carcinomas (PTCs) among cancers as well as TNs with unequivocal cytology (UC) and high percentage of PTCs among cancers. Material and methods: 168 TNs were analysed and eventually surgically treated: 100 UC (50 benign and 50 malignant -90.0% PTCs) and 68 FL (60 benign, 8 malignant -50.0% PTCs). Elasticity score (ES) and strain ratio (SR) were evaluated, and their effectiveness was compared with the evaluation of the number of ultrasound malignancy risk features (NoUMRFs). Results: In the UC group the evaluation of mean values of SR and ES in both sections (meanSR, meanES) was more efficient than NoUMRFs analysis (AUC: 0.903 and 0.869 vs. 0.754, p < 0.05). The following thresholds: meanSR ≥ 2.01, meanES ≥ 2.5, NoUMRFs ≥ 2, were related to the increased malignancy risk in nodules (OR: 45.0; 23.2; 5.4, respectively), but only meanSR ≥ 2.01 was an independent risk factor (OR: 20.3; SEN: 86.0%, SPC: 88.0%). In the FL group, only the evaluation of tSR (SR assessed in transverse section) had the value of AUC > 0.7, and only the set of features: tSR ≥ 1.7 and NoUMRFs ≥ 1 increased the malignancy risk in nodules (OR: 12.0; SEN: 75.0%, SPC: 75.0%). Conclusions: SEG is more reliable than conventional US in the diagnostics of TNs. The efficacy of SEG decreases with lowering percentage of PTCs among cancers. But in FL nodules SEG may support the selection of nodules for surgical treatment. (Endokrynol Pol 2017; 68 (6): 610-622)

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“…the identification of benign nodules [27,43], which is concordant with our results. Few reports are related to the usefulness of SEG in the nodules with an equivocal FNA result.…”

Section: Prace Oryginalnesupporting

confidence: 92%

Section: Prace Oryginalnesupporting

confidence: 92%

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Porównanie skuteczności elastografii w diagnostyce zmian pęcherzykowych tarczycy i ognisk z jednoznacznym wynikiem BAC

Wojtaszek-Nowicka

Słowińska-Klencka

Sporny

et al. 2015

Endokrynologia Polska

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“…Fine needle aspirates are reported as nondiagnostic, nonneoplastic, atypia/follicular lesion, suspicious of malignancy and malignant [7]. Up to 20% of aspirates are nondiagnostic and require repeat puncture [2].…”

Section: Introductionmentioning

confidence: 99%

“…Up to 20% of aspirates are nondiagnostic and require repeat puncture [2]. Cancer rate varies from 20% in the atypia group, to 60% in the suspicious group [7]. Therefore, FNAB is far from being a golden standard, especially due to limitations in its ability to exclude malignancy.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound elastography in thyroid disease

Dudea

Botar-Jid

2015

Med Ultrason

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Thyroid elastography has become, lately, one of the main focuses in thyroid imaging. With more than one hundred papers published on this subject, the core of accumulated knowledge justifies the need for a comprehensive review on the topic. The paper presents the various elastographic techniques used for thyroid assessment. Both strain and shear wave elastography, with all their variants, are discussed. Thereafter the paper proceeds to a detailed description of the technical peculiarities, diagnostic value, limitations and pitfalls for each technique. Although the main accent is placed on thyroid nodules, the applications of elastography in other thyroid disease, diffuse or focal, are also presented. The results of the available metaanalyses are reviewed and the proven value of the technique is highlighted. Still unanswered questions and directions for future research are emphasized, whenever appropriate.

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