Does gastric dilation predict adverse perinatal or surgical outcome in fetuses with gastroschisis?

Alfaraj, Malikah; Ryan, Greg; Langer, Jacob C.; Windrim, Rory; Seaward, P. G. R.; Kingdom, John

doi:10.1002/uog.8868

Cited by 37 publications

(23 citation statements)

References 55 publications

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“…The presence of stomach dilatation was not associated with the outcome measures, which is in agreement with the majority of studies [8,21] . Therefore, according to the present and previous findings [8,21] , stomach dilatation should not be used as a US marker in fetuses with gastroschisis.…”

Section: Discussionsupporting

confidence: 77%

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Sonographic Markers in the Prediction of Fetal Complex Gastroschisis

Andrade

Brizot²,

Rodrigues³

et al. 2017

Fetal Diagn Ther

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Objective: To investigate the ultrasound (US) markers predictive of complex gastroschisis (CG), mortality, and morbidity in fetuses with gastroschisis. Materials and Methods: This was a retrospective cohort study of 186 pregnancies with isolated fetal gastroschisis. Eight US markers were analyzed. The predictions and associations of US markers with CG, mortality, and morbidity were assessed. Combinations of US markers predictive of CG were investigated. Results: Extra-abdominal bowel dilatation (EABD), intra-abdominal bowel dilatation (IABD), and polyhydramnios were predictive of CG. EABD between 25 and 28 weeks had a sensitivity of 64%, a specificity of 89%, a positive predictive value (PPV) of 56.2%, and negative predictive value (NPV) of 91.8%. The predictions of IABD were sensitivity = 26.7%, specificity = 96.7%, PPV = 61.5%, and NPV = 86.8%. The odds ratios for CG in the presence of 1 and 2 US markers, compared with the absence of a US marker, were 18.3 (95% CI, 3.83-87.64) and 73.3 (95% CI, 6.14-876), respectively. Conclusion: US markers predictive of CG were established. The combination of these markers increases the probability of CG.

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Section: Discussionsupporting

confidence: 77%

“…Therefore, according to the present and previous findings [8,21] , stomach dilatation should not be used as a US marker in fetuses with gastroschisis.…”

Section: Discussionmentioning

confidence: 99%

Sonographic Markers in the Prediction of Fetal Complex Gastroschisis

Andrade

Brizot²,

Rodrigues³

et al. 2017

Fetal Diagn Ther

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“…Fetuses with GD diagnosed 30 in a larger study including 98 fetuses, did not find any significant difference among the 2 groups (Table 5). Furthermore, no significant association was found in term of TFEF in fetuses with or without GD (Table 6).…”

Section: Gdmentioning

confidence: 84%

“…There was no study analyzing the association between polyhydramnios and TFEF. Finally, the only study 30 investigating the association between polyhydramnios and time on TPN did not find any significant result (Table 7).…”

Section: Polyhydramniosmentioning

confidence: 88%

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Prenatal Risk Factors and Outcomes in Gastroschisis: A Meta-Analysis

et al. 2015

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BACKGROUND AND OBJECTIVE: Gastroschisis is a congenital anomaly with increasing incidence, easy prenatal diagnosis and extremely variable postnatal outcomes. Our objective was to systematically review the evidence regarding the association between prenatal ultrasound signs (intraabdominal bowel dilatation [IABD], extraabdominal bowel dilatation, gastric dilatation [GD], bowel wall thickness, polyhydramnios, and small for gestational age) and perinatal outcomes in gastroschisis (bowel atresia, intra uterine death, neonatal death, time to full enteral feeding, length of total parenteral nutrition and length of in hospital stay).

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Gastroschisis – what should be told to parents?

Lepigeon¹,

Mieghem

Maurer³

et al. 2014

Prenatal Diagnosis

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Gastroschisis is a common congenital abdominal wall defect. It is almost always diagnosed prenatally thanks to routine maternal serum screening and ultrasound screening programs. In the majority of cases, the condition is isolated (i.e. not associated with chromosomal or other anatomical anomalies). Prenatal diagnosis allows for planning the timing, mode and location of delivery. Controversies persist concerning the optimal antenatal monitoring strategy. Compelling evidence supports elective delivery at 37 weeks' gestation in a tertiary pediatric center. Cesarean section should be reserved for routine obstetrical indications. Prognosis of infants with gastroschisis is primarily determined by the degree of bowel injury, which is difficult to assess antenatally. Prenatal counseling usually addresses gastroschisis issues. However, parental concerns are mainly focused on long-term postnatal outcomes including gastrointestinal function and neurodevelopment. Although infants born with gastroschisis often endure a difficult neonatal course, they experience few long-term complications. This manuscript, which is structured around common parental questions and concerns, reviews the evidence pertaining to the antenatal, neonatal and long-term implications of a fetal gastroschisis diagnosis and is aimed at helping healthcare professionals counsel expecting parents.

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Does gastric dilation predict adverse perinatal or surgical outcome in fetuses with gastroschisis?

Abstract: ABSTRACT

Cited by 37 publications

References 55 publications

Sonographic Markers in the Prediction of Fetal Complex Gastroschisis

Sonographic Markers in the Prediction of Fetal Complex Gastroschisis

Prenatal Risk Factors and Outcomes in Gastroschisis: A Meta-Analysis

Gastroschisis – what should be told to parents?

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