Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence

Metwally, Mostafa; Ong, Kee; Ledger, William; Li, Tin‐Chiu

doi:10.1016/j.fertnstert.2007.07.1290

Cited by 464 publications

(297 citation statements)

References 31 publications

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“…The literature is replete with reports establishing the relationship between lack of antenatal care, facility delivery and increasing risk of stillbirth [24]- [28]. In this study, use of antenatal care is associated with increased risk of stillbirth displaying a dose-response relationship meaning that with increasing number of ANC visits the IRR increases ( Table 3).…”

Section: Discussionmentioning

confidence: 83%

“…The second reason likely to explain this reversed association between ANC, FBD and risk of SB has to do with measurement error. The instrument (that is, the questionnaire)used to collect the relevant information might not have captured the variable precisely or it may be due to the inability of the data collectors to accurately and precisely measure the quantity and quality of intervention received [28].…”

Section: Discussionmentioning

confidence: 99%

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Stillbirth in Nigeria: Rates and Risk Factors Based on 2013 Nigeria DHS

Dahiru¹,

Aliyu²

2016

OALib

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Introduction: Stillbirth remains a public health problem with an estimate of 2.6 million stillbirths in 2015 of which 98% occurred in low-and middle-income countries and over three-quarters of these occurring in Sub-Saharan Africa (SSA) and south Asia. Further, only ten countries carry the burden of over 65% of total stillbirths in the world including Nigeria in the second position. The objective of this analysis is to estimate stillbirth rates and identify the determinants of stillbirth in Nigeria using the 2013 Nigeria DHS data. Methods: The study utilized the nationally-representative sample of women of reproductive age interviewed during the 2013 Nigeria DHS. Analysis was restricted to 31,671 women aged 15 -49 years who had a pregnancy reaching at least seven months of gestation in the five-year period prior to the survey. Descriptive statistics and regression analysis were performed using Stata v13 to determine significant factors related to stillbirth. Incidence Risk Ratio (IRR) was used to assess strength of association between independent and dependent variables. Results: Overall stillbirth rate is 12.5 per 1000 pregnancies, with rates as high as 22 per 1000 (among women aged 15 -19 years) and as low as 6.4 per 1000 (among women who received skilled ANC). Age, household wealth, higher birth order, facility delivery, Caesarean delivery, rural residence and ever use of contraceptive are consistent determinants of stillbirth in both the bivariate and multivariate models. Women in rich households have lower IRR of stillbirth (0.60; 95% CI: 0.45 -0.59) as well as women who had ever used modern contraception (IRR = 0.72; 95% CI: 0.63 -0.81). However, health facility deliveries as well as deliveries through a C-section, rural residence and age older than 20 years all carry increased risk of stillbirth (IRR = 1.81; 95% CI: 1.05 -1.33), (IRR = 2.46; 95% CI: 2.03 -2.98), (IRR = 1.41; 95% CI: 1.24 -1.59), and (IRR = 2.23; 95% CI: 1.75 -2.59) respectively. Conclusions: The study revealed that there are several factors responsible for stillbirth in Nigeria. Age, household wealth, higher birth order, facility delivery, Caesarean delivery, rural residence and ever use of contraceptive are consistent determinants of stillbirth in both the bivariate and multivariate models. There is urgent need by the National government to improve quality of maternal health care services and interventions to improve utilization and quality of prenatal care.

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Section: Discussionmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Stillbirth in Nigeria: Rates and Risk Factors Based on 2013 Nigeria DHS

Dahiru¹,

Aliyu²

2016

OALib

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“…Obese women undergoing infertility treatment should be counseled regarding the negative impact that obesity has on IVF outcomes and encouraged to participate in weight loss programs to maximize their success rates. disorders, fetal macrosomia, stillbirth, and congenital anomalies [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Increased body mass index negatively impacts blastocyst formation rate in normal responders undergoing in vitro fertilization

Comstock

Kim

Behr

et al. 2015

J Assist Reprod Genet

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Purpose The aim of this study is to investigate the effect of female BMI and metabolic dysfunction on blastocyst formation rate. Methods This was a retrospective cohort study that was performed in an academic center for reproductive medicine. Patients who were normal weight, overweight with metabolic dysfunction, or obese who had ≥6 oocytes retrieved in a fresh IVF cycle were included in the study. The blastocyst formation rate was calculated from the number of ≥5 cell embryos on day 3 observed in culture until day 5 or day 6. Only good quality blastocysts were included in the calculation as defined by a morphologic grade of 3BB or better. Results The blastocyst formation rate was significantly better in the normal-weight controls versus overweight/obese patients (57.2 versus 43.6 %, p<0.007). There was no difference in blastocyst formation between the patients with a BMI 25-29.9 kg/m 2 with metabolic dysfunction and those with a BMI ≥30 kg/m 2 . Conclusion The maternal metabolic environment has a significant impact on embryo quality as measured by blastocyst formation. A decreased blastocyst formation rate is likely a significant contributor to poorer reproductive outcomes in overweight and obese women with infertility.

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“…For instance, men's facial attractiveness correlates with both sperm morphology and motility (Soler et al, 2003), and both men and women with attractive faces may be healthier than their less attractive counterparts (Shackelford & Larsen, 1999). Similarly, body size and shape are important cues to women's fertility status (Hamilton-Fairley, Kiddy, Watson, & Franks, 1992;Singh, 1993) and likelihood of miscarriage (Metwally, Ong, Ledger, & Li, 2008). Various dimensions of physical attractiveness have therefore been linked to mating success indices.…”

Section: Introductionmentioning

confidence: 99%

Cosmetic Surgery as Intrasexual Competition: The Mediating Role of Social Comparison

Arnocky¹,

Piché²

2014

PSYCH

105

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Cosmetic surgical procedures have previously been associated with some risks to psychological and physical health. Yet such procedures are on the rise, highlighting the need for a better understanding of the factors which might underlie the decision to undergo cosmetic surgery. In a sample of 297 young adults (192 women), we examined the relationship between intrasexual competition (IC), social comparison, and individuals' attitudes, perceived risks, and desired spending on cosmetic surgical procedures. Results showed that women perceived more risk to cosmetic surgery, yet held more positive attitudes and desire to spend on cosmetic surgery compared to men. For both men and women, IC predicted positive attitudes and desired spending on cosmetic surgery. Social comparison mediated all relationships between IC and cosmetic surgery variables. Cosmetic surgery is discussed as a potential form of intrasexual competition rooted in the mate-preferences of the opposite sex.

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Does high body mass index increase the risk of miscarriage after spontaneous and assisted conception? A meta-analysis of the evidence

Cited by 464 publications

References 31 publications

Stillbirth in Nigeria: Rates and Risk Factors Based on 2013 Nigeria DHS

Stillbirth in Nigeria: Rates and Risk Factors Based on 2013 Nigeria DHS

Increased body mass index negatively impacts blastocyst formation rate in normal responders undergoing in vitro fertilization

Cosmetic Surgery as Intrasexual Competition: The Mediating Role of Social Comparison

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