Does level of leisure time physical activity, in a sample of patients with depression, predict health care utilization over a subsequent 5-year period? Findings from a Finnish cohort study

Raatikainen, Ilkka; Vanhala, Mauno; Mäntyselkä, Pekka; Heinonen, Ari; Koponen, Hannu; Kautiainen, Hannu; Korniloff, Katariina

doi:10.1016/j.mhpa.2018.06.007

Cited by 6 publications

(6 citation statements)

References 39 publications

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“…Blood pressure was measured twice after 15 min rest time with a mercury sphygmomanometer and the patient in a sitting position. The physical examination was conducted by trained study nurses [22]. The body mass index (BMI) was defined as the person's weight (kg) divided by the square of the height (m).…”

Section: Methodsmentioning

confidence: 99%

Does baseline leisure-time physical activity level predict future depressive symptoms or physical activity among depressive patients? Findings from a Finnish five-year cohort study

Raatikainen

Mäntyselkä

Heinonen

et al. 2020

Nordic Journal of Psychiatry

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Objectives: The aims of this study were to investigate whether baseline leisure-time physical activity (LTPA) is associated with future recovery from depression among patients with a depression diagnosis and whether baseline LTPA is associated with total physical activity after five years of follow-up. Methods: A total of 258 patients aged 35 years with clinically confirmed depression at baseline participated. The study was conducted between 2008 and 2016 in municipalities within the Central Finland Hospital District. Depressive symptoms (DS) were determined with the Beck Depression Inventory (BDI) with a cutoff score 10, and depression diagnoses were confirmed by the Mini-International Neuropsychiatric Interview (MINI). Blood pressure and anthropometric parameters were measured and blood samples for glucose and lipid determinations were drawn at baseline. LTPA, physical activity, and other social and clinical factors were captured by standard self-administered questionnaires at baseline and the five-year follow-up point. Results: Of the 258 patients, 76 (29%) had DS at follow-up. Adjusted odds ratio (OR) for future DS was 1.43 (confidence interval [CI] 0.69-2.95) for participants with moderate LTPA and 0.92 (CI 0.42-2.00) for participants with high LTPA, compared with low LTPA at baseline. Higher baseline LTPA levels were associated with higher total physical activity in the future (b¼0.14 [95% CI: 0.02-0.26] for linearity ¼ 0.024). Conclusion: Baseline LTPA did not affect the five-year prognosis of depression among depressed patients in a Finnish adult population. Because the baseline LTPA level predicted the future total physical activity, it could be included as a part of the overall health management and treatment of depression in clinical practices.

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Section: Methodsmentioning

confidence: 99%

Does baseline leisure-time physical activity level predict future depressive symptoms or physical activity among depressive patients? Findings from a Finnish five-year cohort study

Raatikainen

Mäntyselkä

Heinonen

et al. 2020

Nordic Journal of Psychiatry

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“…Leisure-time physical activity (number of 30-min exercise sessions) was delineated with the question: "How often do you engage in physical activity for at least half an hour so that you are out of breath and sweating?" Replies were classified as low (0-2 sessions per month), moderate (1-2 sessions per week), or high (three or more sessions per week) (16,25).…”

Section: Methodsmentioning

confidence: 99%

The influence of restless legs symptoms on musculoskeletal pain in depression

Auvinen

Koponen

Kautiainen

et al. 2020

Scandinavian Journal of Pain

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Background and aimsRestless legs syndrome is a sensorimotor disorder associated with mental health conditions notably depression. Restless legs symptoms and depression are commonly associated with pain. The study investigated the influence of restless legs symptoms on musculoskeletal pain in patients with depression or with increased depressive symptoms.MethodsA cross-sectional study of primary care patients in the Central Finland Hospital District. The prevalence of restless legs symptoms was studied in patients with depressive symptoms (n = 695) and controls without a psychiatric diagnosis (n = 410) by using a structured questionnaire. The depressive symptoms were evaluated with the Beck Depression Inventory and the psychiatric diagnosis was confirmed by means of a diagnostic interview (MINI). The prevalence and intensity of musculoskeletal pain was captured with form-based questions. A single-question screen for restless legs symptoms was applied.ResultsThere was a significant difference in the prevalence of continuous widespread musculoskeletal pain between the three study groups: the controls 4.6% (95% CI: 2.8–7.1), the patients with symptoms of depression without a diagnosis 16.0% (11.7–21.1), and the patients with diagnosed depression 22.1% (18.3–23.3) (p = 0.006 after being adjusted for age, sex, smoking, use of alcohol, education years, body mass index, use of antidepressants, and physical activity, after multiple corrections, all groups were significantly different from each other). Compared with those not having restless legs symptoms, subjects with restless legs symptoms had more often continuous widespread musculoskeletal pain in the control subjects (p = 0.001; 2.3% vs. 10.5%) and in the patients with depressive symptoms without a depression diagnosis (p = 0.024; 9.1 vs. 18.7%) but not in those with diagnosed depression (p = 0.98; 19.5 vs. 19.4%). The restless legs symptoms were associated with the intensity of pain in all groups (p < 0.001).ConclusionsRestless legs symptoms were related to continuous widespread musculoskeletal pain in subjects without depressive symptoms and in patients with depressive symptoms without a depression diagnosis. Pain intensity was higher in the subjects with restless legs symptoms regardless of depressive symtoms or depression.ImplicationsClinical management of pain in patients with restless legs symptoms should include an increased focus on the prevention and treatment of either conditions.

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“…The study protocol was approved by the Ethics Committee of the Central Finland Hospital District. The FDMSA -study has been reported in previous studies [31][32][33][34][35].…”

Section: Methodsmentioning

confidence: 99%

“…Leisure-time physical activity was determined with the question:" How often do you do physical activity at least half on hour so that you are out of breath and sweating?" then answers were classified as low (0-2 sessions per month), moderate (1-2 sessions per week), or high (three or more sessions per week) [35].…”

Section: Methodsmentioning

confidence: 99%

Elevation of tumor necrosis factor alpha levels is associated with restless legs symptoms in clinically depressed patients

Auvinen

Mäntyselkä

Koponen

et al. 2018

Journal of Psychosomatic Research

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Background: Restless legs syndrome is a sensorimotor disorder associated with several mental illnesses particularly depression. Methods: A cross-sectional study of primary care patients. The prevalence of restless legs symptoms was studied in 706 patients with depressive symptoms and 426 controls without a psychiatric diagnosis by using a structured questionnaire. The depressive symptoms were evaluated with the BDI and the psychiatric diagnosis was confirmed by means of a diagnostic interview (M.I.N.I.). The subjects with elevated depressive symptoms were divided into two groups subjects with depressive symptoms with and without clinical depression. Results: The prevalence of restless legs symptoms was 24.8% in the controls, 50.0% in the patients with clinical depression and 42.4% in the patients with depressive symptoms. CRP value was significantly higher (p = .003) in the clinically depressed patients than in the other groups. There was a higher concentration of TNF-α in the subjects with restless legs symptoms (7.4 ng/l ± 3.2) compared with the subjects without symptoms (6.7 ng/ l ± 2.3)(p < .001). There was a significant difference in the TNF-α levels between the subjects with and without restless legs symptoms in the depression group (p < .001) and among the patients with depressive symptoms but no a depression diagnosis (p = .022). In these groups, restless legs symptoms were associated with elevated levels of TNF-α. Conclusions: TNF-α level was associated with restless legs symptoms only among subjects with depressive symptoms whether they had clinical depression or not. We suggest that TNF-α could be an underlying factor between restless legs symptoms and comorbidities.

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Does level of leisure time physical activity, in a sample of patients with depression, predict health care utilization over a subsequent 5-year period? Findings from a Finnish cohort study

Cited by 6 publications

References 39 publications

Does baseline leisure-time physical activity level predict future depressive symptoms or physical activity among depressive patients? Findings from a Finnish five-year cohort study

Does baseline leisure-time physical activity level predict future depressive symptoms or physical activity among depressive patients? Findings from a Finnish five-year cohort study

The influence of restless legs symptoms on musculoskeletal pain in depression

Elevation of tumor necrosis factor alpha levels is associated with restless legs symptoms in clinically depressed patients

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