Results: Cannulation of the desired duct was successful in 89.2% of 825 ERCPs with no earlier sphincterotomy. Complete stone removal was achieved in 91.3% of procedures. standard biliary sphincterotomy was performed in 73.8% and precut sphincterotomy in 12.0 % of cases. Cholangitis developed in 2.1%, bleeding in 1.9%, pancreatitis in 1.9%, perforation in 1.0% and cardio-pulmonary or miscellaneous complications in 4.2% of cases. the majority of complications could be managed conservatively. in procedures with no earlier sphincterotomy ERCP-related 30-day mortality was 0.2% (n = 2) and overall 30-day mortality was 3.3% (n = 27).Conclusions: ERCP indications and success rates, as well as morbidity and mortality were comparable to those reported earlier. although the success rate of cannulation and thereby ERCP procedures seem to be somewhat lower than in tertiary referral centres, ERCP procedures can be safely performed in a low-volume ERCP unit by concentrating procedures on a few experienced endoscopists. the success rates may be further improved with the latest cannulation techniques, used selectively in the last years of the study period.