Does Revascularization Prior to Foot and Ankle Surgery Reduce the Incidence of Surgical Site Infection (SSI)?

Abstract

Recommendation: Several studies support the effect of peripheral vascular disease (PVD) on wound healing and surgical site infection (SSI). Despite this, there have been no specific studies proving the beneficial effect of revascularization on SSI prior to operative intervention in the setting of traumatic or elective foot and ankle surgery. The majority of studies on revascularization are in the setting of diabetic foot infection or established ischemia. We recommend that in the presence of an inadequate vascularization in the foot and ankle, vascular optimization should be undertaken prior to elective surgery. Level of Evidence: Limited. Delegate Vote: Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus)

Risk factors of wound infection after lung transplantation: a narrative review

“…As a traumatic procedure, lung transplantation can also promote systemic stress response in the body, aggravating the degree of insulin resistance and further increasing the risk of incision infection (35). Insulin resistance will suppress the secretion of pancreatic islet beta-cells, promoting protein decomposition, reducing protein synthesis, delaying fibroblasts, reducing the synthesis of fiber, and slowing down the generation of new capillaries and maturation of granulation tissue, delaying healing and increasing the probability of infection (36). Therefore, for lung transplantation patients with type 2 diabetes, blood glucose fluctuation should be strictly controlled during the perioperative period.…”