Does three-dimensional surgery affect recurrence patterns in patients with gastric cancer after laparoscopic R0 gastrectomy? Results from a 3-year follow-up phase III trial

Lü, Jun; Xu, Binbin; Zheng, Zhifang; Xie, Jian‐Wei; Wang, Jia-Bin; Ji, Lin; Chen, Qi‐Yue; Cao, Long‐Long; Ma, Lin; Tu, Ru‐Hong; Huang, Ze-Ning; Zheng, Chao-Hui; Huang, Chang‐Ming; Li, Ping

doi:10.1007/s00464-020-07367-0

Cited by 4 publications

(3 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After the matching under propensity scores, there was no significant difference in the overall survival rate of patients in the 2 years after surgery between the experimental group and the control group ( P > 0.05). The existing researches pointed out no statistically significant difference in the long-term efficacies of advanced gastric cancer with laparoscopic surgery and traditional open surgery [ 24 ]. It was concluded that the Da Vinci robotic surgery system was the same as laparoscopic surgery in terms of radical resection of distal gastric cancer.…”

Section: Discussionmentioning

confidence: 99%

Da Vinci Robot-Assisted Video Image Processing under Artificial Intelligence Vision Processing Technology

Cheng

Ya-jun

2022

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

This research was aimed to explore the application value of intelligent algorithm-based digital images in Da Vinci robot-assisted treatment of patients with gastric cancer surgery. 154 patients were included as the research objects, with 89 cases in the control group underwent laparoscopic surgery, and 65 cases in the experimental group underwent robotic surgery. According to the propensity score, the patients in two groups were pair matched (1: 1), of which 104 cases (52 cases in each group) were successfully matched. The general data of patients, the changes in the images before and after the algorithm processing, the intraoperative and postoperative conditions, the pathological examination results, and the follow-up information were observed after matching. Compared with the original images, the images processed by the thread image edge detection algorithm had the significantly improved clarity, as well as highly reduced artifacts and noises. The sensitivity, specificity, and accuracy of image-assisted diagnosis were improved remarkably, showing the differences of statistical significance ( P < 0.05 ). The total time of surgery, intraoperative bleeding, CRP (1d and 3d after surgery), and postoperative total abdominal drainage showed the significant differences as well ( P < 0.05 ). The surgeries of patients in both groups met R0 resection (no tumor infiltration within 1 mm of the surgical margin), but there was a significant difference in the number of lymph node dissections ( P < 0.05 ). The overall survival rates of patients in the experimental group and the control group were 83.0% and 76.1%, respectively, 2 years after surgery, with no significant difference ( P > 0.05 ). The thread image edge detection algorithm produced a better processing effect on the images, which greatly improved the diagnostic sensitivity, specificity, and accuracy. Compared with endoscopic surgery, robotic surgery has better postoperative recovery, safety and reliability, and obvious advantages of minimally invasive surgery.

show abstract

Section: Discussionmentioning

confidence: 99%

Da Vinci Robot-Assisted Video Image Processing under Artificial Intelligence Vision Processing Technology

Cheng

Ya-jun

2022

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

show abstract

“…The CLASS-04 trial (ClinicalTrials.gov, NCT02845986) enrolled 251 patients between September, 2016 and October, 2017 to evaluate the safety and feasibility of LSPSHL for LAPGC, conducted at specialized institutions of the Chinese Laparoscopic Gastrointestinal Surgery Study group [9]. The FUGES-001 trial (ClinicalTrials.gov, NCT02327481) enrolled 438 patients between January, 2015 and April, 2016 to determine the efficiency of 3D LG and 2D LG in GC, conducted at Fujian Medical University Union Hospital (FMUUH) [29,30]. The FUGES-002 trial (Clinical-Trials.gov, NCT02333721) enrolled 536 patients between January, 2015 and December, 2018 to evaluate the surgical outcomes of LSPSHL for non-Gre-invading LAPGC, conducted at FMUUH.…”

Section: Participantsmentioning

confidence: 99%

“…Each of the four studies were approved by their institution's local ethics committee. Operative techniques, definitions of study endpoints, and results of these studies have been reported previously [9,[29][30][31]. Heterogeneity between the four trials was minimized by the use of the same laparoscopic surgery procedure.…”

Section: Participantsmentioning

confidence: 99%

Reappraise role of No. 10 lymphadenectomy for proximal gastric cancer in the era of minimal invasive surgery during total gastrectomy: a pooled analysis of 4 prospective trial

Zhong

Chen

et al. 2020

Gastric Cancer

Self Cite

View full text Add to dashboard Cite

Background For patients with locally advanced proximal gastric cancer (LAPGC), the individualized selection of patients with highly suspected splenic hilar (No. 10) lymph node (LN) metastasis to undergo splenic hilar lymphadenectomy, is a clinical dilemma. This study aimed to re-evaluate the feasibility and safety of laparoscopic spleen-preserving splenic hilar lymphadenectomy (LSPSHL) and to identify the population who would benefit from it. Methods A total of 1068 patients (D2 group = 409; D2 + No. 10 group = 659) who underwent laparoscopic total gastrectomy from four prospective trials between January 2015 and July 2019 were analyzed. Results No significant difference in the incidence (16.9% vs. 16.4%; P = 0.837) of postoperative complications were found between the two groups. The metastasis rate of No. 10 LN among patients in the D2 + No. 10 group was 10.3% (68/659). Based on the decision tree, patients with LAPGC with tumor invading the greater curvature (Gre), patients with non-Greinvading LAPGC with a tumor size > 5 cm and clinical positive locoregional LNs were defined as the high-priority No. 10 dissection group. The metastasis rate of No. 10 LNs in the high-priority group was 19.4% (41/211). In high-priority group, the 3-year overall survival of the D2 + No. 10 group was better than that of the D2 group (74.4% vs. 42.1%; P = 0.005), and the therapeutic index of No. 10 was higher than the indices of most suprapancreatic stations. Conclusions LSPSHL for LAPGC is safe and feasible when performed by experienced surgeons. LSPSHL could be recommended for the high-priority group patients even without invasion of the Gre.

show abstract

Comparative Study of the Short-Term Outcomes and Long-Term Outcomes using Total 3D and 2D Laparoscopic Distal Gastrectomy with Delta-Shaped Anastomosis for Gastric Cancer

Zhang,

Luan,

Wang

et al. 2023

Indian J Surg

View full text Add to dashboard Cite

Does three-dimensional surgery affect recurrence patterns in patients with gastric cancer after laparoscopic R0 gastrectomy? Results from a 3-year follow-up phase III trial

Cited by 4 publications

References 38 publications

Da Vinci Robot-Assisted Video Image Processing under Artificial Intelligence Vision Processing Technology

Da Vinci Robot-Assisted Video Image Processing under Artificial Intelligence Vision Processing Technology

Reappraise role of No. 10 lymphadenectomy for proximal gastric cancer in the era of minimal invasive surgery during total gastrectomy: a pooled analysis of 4 prospective trial

Comparative Study of the Short-Term Outcomes and Long-Term Outcomes using Total 3D and 2D Laparoscopic Distal Gastrectomy with Delta-Shaped Anastomosis for Gastric Cancer

Contact Info

Product

Resources

About