Does topical lidocaine before tracheal intubation attenuate airway responses in children? An observational audit

Abstract

The incidence of desaturation was higher in patients receiving TAL compared with children who did not. This association should perhaps be considered when contemplating the use of this technique.

Effects of intravenous and topical laryngeal lidocaine on heart rate, mean arterial pressure and cough response to endotracheal intubation in dogs

“…Hamilton et al. () reported that topical lidocaine failed to suppress the cough response at ETI in children and was in fact associated with a higher incidence of desaturation than when it was not administered.…”

Adult and pediatric anesthesia/sedation for gastrointestinal procedures outside of the operating room

“…The administration of intravenous lidocaine or of topical lidocaine spray for the airway attenuates laryngeal and respiratory reflex responses such as coughing, expiration reflex, spasmodic panting, and apnea [61][62][63]. This facilitates the insertion of a laryngoscope or video laryngoscope, tracheal tube, LMA, bronchoscope, or an endoscope for gastrointestinal procedures.…”

Anesthesia in children with a cold

“…Some authors state that its topical use has protective effects against coughing and laryngospasm [28], whereas others did not find positive effects or even showed an increase in respiratory adverse events [29]. Hamilton et al [29] investigated more than 1000 children for elective general anesthesia with endotracheal intubation and found a significantly higher rate of desaturation in children treated with topical lidocaine compared with the placebo group. In this study, no difference in the incidence of laryngospasm was found.…”